Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Jude E. Uzonna"'
Autor:
Romaniya Zayats, Zhirong Mou, Atta Yazdanpanah, Gaurav Gupta, Paul Lopez, Deesha Nayar, Wan H. Koh, Jude E. Uzonna, Thomas T. Murooka
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Cutaneous Leishmania major infection elicits a rapid T cell response that is insufficient to clear residually infected cells, possibly due to the accumulation of regulatory T cells in healed skin. Here, we used Leishmania-specific TCR transg
Externí odkaz:
https://doaj.org/article/e9169ab2405b4fc58156443a44308eab
Autor:
Chidalu A. Edechi,, Nnamdi M. Ikeogu, Lucas Evangelista de Lima Terceiro, Jude E. Uzonna, Yvonne Myal
Publikováno v:
European Medical Journal, Vol 5, Iss 3, Pp 55-62 (2020)
The underlying mechanisms of metastasis in patients with breast cancer is still poorly understood. Approximately 6% of patients with breast cancer present with metastasis at the time of diagnosis. Metastatic breast cancer is difficult to treat and pa
Externí odkaz:
https://doaj.org/article/84c70025a8294d27af0b54cbafdfb5f9
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Intravital microscopy, such as 2-photon microscopy, is now a mainstay in immunological research to visually characterize immune cell dynamics during homeostasis and pathogen infections. This approach has been especially beneficial in describing the c
Externí odkaz:
https://doaj.org/article/65df8d197ed9480fae470a39bf9b8754
Autor:
Chidalu A. Edechi, Nnamdi M. Ikeogu, Gloria N. Akaluka, Lucas E. L. Terceiro, Mikayla Machado, Enitan S. Salako, Aida F. Barazandeh, Sam K. P. Kung, Jude E. Uzonna, Yvonne Myal
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The prolactin inducible protein (PIP) is expressed to varying degrees in more than 90% of breast cancers (BCs). Although high levels of PIP expression in BC has been shown to correlate with better prognosis and patient response to chemotherapy, some
Externí odkaz:
https://doaj.org/article/f36d7e051a3241f6ba0361ac678aade6
Autor:
Gaurav Gupta, Zhirong Mou, Ping Jia, Rohit Sharma, Romaniya Zayats, Sayonara M. Viana, Lianyu Shan, Aldina Barral, Viviane S. Boaventura, Thomas T. Murooka, Abdel Soussi-Gounni, Camila I. de Oliveira, Jude E. Uzonna
Publikováno v:
Cell Reports, Vol 33, Iss 11, Pp 108513- (2020)
Summary: The long pentraxin 3 (PTX3) plays a critical role in inflammation, tissue repair, and wound healing. Here, we show that PTX3 regulates disease pathogenesis in cutaneous leishmaniasis (CL). PTX3 expression increases in skin lesions in patient
Externí odkaz:
https://doaj.org/article/aaefd71d64124fd1a867b9f493e7fb4a
Autor:
Faith Osier, Jude E. Uzonna
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/20bd3e961b0a4df0879258d89b4fad86
Autor:
Shiby Kuriakose, Chukwunonso Onyilagha, Rani Singh, Folayemi Olayinka-Adefemi, Ping Jia, Jude E. Uzonna
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
It is known that Trypanosoma congolense infection in mice is associated with increased production of proinflammatory cytokines by macrophages and monocytes. However, the intracellular signaling pathways leading to the production of these cytokines st
Externí odkaz:
https://doaj.org/article/2a1245ef430f43aa9f85bd7b443b6da8
Autor:
Emeka B. Okeke, Jude E. Uzonna
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The distinction between innate and adaptive immunity is one of the basic tenets of immunology. The co-operation between these two arms of the immune system is a major determinant of the resistance or susceptibility of the host following pathogen inva
Externí odkaz:
https://doaj.org/article/a08757317e304521ae8c90b49a379933
Autor:
Nnamdi M. Ikeogu, Gloria N. Akaluka, Chidalu A. Edechi, Enitan S. Salako, Chukwunonso Onyilagha, Aida F. Barazandeh, Jude E. Uzonna
Publikováno v:
Microorganisms, Vol 8, Iss 8, p 1201 (2020)
Parasitic diseases still constitute a major global health problem affecting billions of people around the world. These diseases are capable of becoming chronic and result in high morbidity and mortality. Worldwide, millions of people die each year fr
Externí odkaz:
https://doaj.org/article/d5a70b2bc25049a3a66d7d9706f1c0ef
Publikováno v:
Cancers, Vol 11, Iss 8, p 1080 (2019)
Breast cancer affects millions of women worldwide, leading to many deaths and significant economic burden. Although there are numerous treatment options available, the huge potentials of immunotherapy in the management of localized and metastatic bre
Externí odkaz:
https://doaj.org/article/3842a13192a4460f85292561d7421d8c