Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jude E Onyia"'
Publikováno v:
BioTechniques, Vol 28, Iss 3, Pp 506-510 (2000)
Luciferase reporter vectors are commonly used for the functional analysis of basal promoter and enhancer elements of eukaryotic genes. Randomly occurring cisacting elements in the vector sequences that can spuriously respond to various transcription
Externí odkaz:
https://doaj.org/article/acc69be2483a415b8bc7b914ff488361
Autor:
N.H. Kulkarni, Ling Yeong Chia, Matthew T. Gillespie, T. J. Martin, Jonathan H. Gooi, Jude E. Onyia, P.W.M. Ho, Nicole C. Walsh, Ivo Kalajzic, J.M.W. Quinn, B. Han, Natalie A. Sims, S. H M McAhren, Morten A. Karsdal, S. Pompolo
Publikováno v:
Bone. 46:1486-1497
The therapeutic goal of increasing bone mass by co-treatment of parathyroid hormone (PTH) and an osteoclast inhibitor has been complicated by the undefined contribution of osteoclasts to the anabolic activity of PTH. To determine whether active osteo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0923585224ad02adfa4c4ef1e025950a
https://doi.org/10.1016/j.bone.2010.02.018
https://doi.org/10.1016/j.bone.2010.02.018
Autor:
John E. Hale, Jude E. Onyia, Shuang Luo, Michael D. Knierman, Derrick R. Witcher, Jesus A. Gutierrez, Jill A. Willency, Douglas Perkins, Zhaoyan Jin, Patricia J. Solenberg
Publikováno v:
Proceedings of the National Academy of Sciences. 105:6320-6325
The peptide hormone ghrelin is the only known protein modified with an O-linked octanoyl side group, which occurs on its third serine residue. This modification is crucial for ghrelin's physiological effects including regulation of feeding, adiposity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9cc40168f9313ca683000dd37b4d9d3
https://doi.org/10.1073/pnas.0800708105
https://doi.org/10.1073/pnas.0800708105
Autor:
Tao Wei, J.M.W. Quinn, Jonathan H. Gooi, S. Pompolo, Natalie A. Sims, Matthew T. Gillespie, K D Hausler, Blessing Crimeen-Irwin, Jude E. Onyia, E H Allan, T. John Martin
Publikováno v:
Journal of Bone and Mineral Research. 23:1170-1181
With the aim of identifying new pathways and genes regulated by PTH(1-34) and PTH-related protein 1-141 [PTHrP(1-141)] in osteoblasts, this study was carried out using a mouse marrow stromal cell line, Kusa 4b10, that acquires features of the osteobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe6fc8ea44837ce6898f9b82f4ca31b9
https://doi.org/10.1359/jbmr.080324
https://doi.org/10.1359/jbmr.080324
Autor:
Melissa A. Schreiweis, Jude E. Onyia, N.H. Kulkarni, Jon P. Butler, David L. Halladay, Richard E. Higgs, Michael D. Knierman, John E. Hale
Publikováno v:
Journal of Cellular Biochemistry. 101:466-476
The non-mineral component of bone matrix consists of 90% collagenous, 10% non-collagenous proteins. These proteins regulate mineralization, growth, cell signaling and differentiation, and provide bone with its tensile strength. Expression of bone mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9dafc0a271e8d9dae1ece928e2a649b
https://doi.org/10.1002/jcb.21196
https://doi.org/10.1002/jcb.21196
Autor:
Xi Lin, Jianyong Shou, Lawrence M. Gelbert, Jude E. Onyia, Jonathan M. Yingling, Eric Wen Su, Birong Liao, Xingdong Feng, Shuyu Li, Shuguang Huang, Xiang Ye
Publikováno v:
Genomics, Proteomics & Bioinformatics
To determine cancer pathway activities in nine types of primary tumors and NCI60 cell lines, we applied an in silica approach by examining gene signatures reflective of consequent pathway activation using gene expression data. Supervised learning app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42a5c637a4cdf0506e428bf15def1aec
https://doi.org/10.1016/s1672-0229(07)60010-2
https://doi.org/10.1016/s1672-0229(07)60010-2
Autor:
Richard E. Higgs, Thomas A. Engler, Henry Uhlman Bryant, Ernst R. Dow, Mathias N'Cho, Bruce D. Gitter, Jude E. Onyia, Jianyong Shou, Trent R. Stewart, David L. Halladay, Tao Wei, T. John Martin, Yanfei L. Ma, Diane L. Sterchi, Amar Kumar, N.H. Kulkarni
Publikováno v:
Journal of Cellular Biochemistry. 102:1504-1518
Parathyroid hormone (PTH) and glycogen synthase kinase-3 (GSK-3) inhibitor 603281-31-8, administered once daily increased bone formation in vivo. We investigated the molecular mechanisms of the anabolic responses of PTH and 603281-31-8 in rat osteope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6dfee062afef2e3f0ef7661e0c47e9
https://doi.org/10.1002/jcb.21374
https://doi.org/10.1002/jcb.21374
Autor:
S. Huang, T.A. Grese, Henry Uhlman Bryant, P. Chen, Masahiko Sato, Jude E. Onyia, J.A. Dodge, Leah M. Helvering, Shawn T. Estrem, Ernst R. Dow, A.G. Geiser, Rebecca R. Miles, David L. Halladay, S.A. Jones, M.D. Adrian, Y.L. Ma, John N. Calley, Tao Wei
Publikováno v:
Biology of Reproduction. 72:830-841
A detailed analysis of the differential effects of estrogen (E) compared to raloxifene (Ral), a selective estrogen receptor modulator (SERM), following estrogen receptor (ER) binding in gynecological tissues was conducted using gene microarrays, Nort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826627eaf05aae36ec7bb127fba0f926
https://doi.org/10.1095/biolreprod.104.034595
https://doi.org/10.1095/biolreprod.104.034595
Autor:
Henry Uhlman Bryant, M. Zhang, Leah M. Helvering, N.H. Kulkarni, Sutada Lotinun, Charles A. Frolik, Jude E. Onyia, Yanfei L. Ma, Avudaiappan Maran, Rebecca R. Miles, Emily M. Ambrose, Peining Chen, Lawrence M. Gelbert, Tao Wei, Masahiko Sato, Ernst R. Dow, Xi Lin, David L. Halladay, Russell T. Turner, Shuguang Huang
Publikováno v:
Journal of Cellular Biochemistry. 95:403-418
Teriparatide, human PTH (1-34), a new therapy for osteoporosis, elicits markedly different skeletal responses depending on the treatment regimen. In order to understand potential mechanisms for this dichotomy, the present investigation utilized micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c743b61513b4574818eb566546df622b
https://doi.org/10.1002/jcb.20438
https://doi.org/10.1002/jcb.20438
Autor:
Keith M. Goldstein, James L. Stevens, Jean-Marie Colet, Shawn T. Estrem, B. L. Ackermann, J. A. Eckstein, Craig E. Thomas, Timothy P. Ryan, N.H. Kulkarni, Leah M. Helvering, B. Liao, Jude E. Onyia, J. Shou, Robert A. Jolly, Tao Wei
Publikováno v:
Biomarkers. 10:153-172
High-throughput molecular-profiling technologies provide rapid, efficient and systematic approaches to search for biomarkers. Supervised learning algorithms are naturally suited to analyse a large amount of data generated using these technologies in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd020c11dba99a40a743c981c7e6372
https://doi.org/10.1080/13547500500107430
https://doi.org/10.1080/13547500500107430