DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes

Autor: Samwer, Matthias, Schneider, Maximilian W.G., Hoefler, Rudolf, Schmalhorst, Philipp S., Jude, Julian G., Zuber, Johannes, Gerlich, Daniel W.

Publikováno v: In Cell 24 August 2017 170(5):956-972

A targeted knockdown screen of genes coding for phosphoinositide modulators identifies PIP4K2A as required for acute myeloid leukemia cell proliferation and survival.

Autor: Jude JG; Inositide Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, M20 4BX, United Kingdom.; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, M20 4BX, United Kingdom., Spencer GJ; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, M20 4BX, United Kingdom., Huang X; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, M20 4BX, United Kingdom., Somerville TDD; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, M20 4BX, United Kingdom., Jones DR; Inositide Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, M20 4BX, United Kingdom., Divecha N; Inositide Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, M20 4BX, United Kingdom., Somervaille TCP; Leukaemia Biology Laboratory, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, M20 4BX, United Kingdom.

Publikováno v: Oncogene [Oncogene] 2015 Mar 05; Vol. 34 (10), pp. 1253-1262. Date of Electronic Publication: 2014 Mar 31.