Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Judd C. Rice"'
Autor:
Benjamin H. Weekley, Judd C. Rice
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-20 (2023)
Abstract Background Proteolysis of the histone H3 N-terminal tail (H3NT) is an evolutionarily conserved epigenomic feature of nearly all eukaryotes, generating a cleaved H3 product that is retained in ~ 5–10% of the genome. Although H3NT proteolysi
Externí odkaz:
https://doaj.org/article/8a6f2d2abaf544b388ee38a91e1437d7
Autor:
Judd C. Rice, Benjamin H. Weekley, Tomas Kanholm, Zhihui Chen, Sunyoung Lee, Daniel J. Fernandez, Rachel Abrahamson, Alessandra Castaldi, Zea Borok, Brian D. Dynlacht, Woojin An
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-12 (2021)
Abstract Background Selective proteolysis of the histone H3 N-terminal tail (H3NT) is frequently observed during eukaryotic development, generating a cleaved histone H3 (H3cl) product within a small, but significant, portion of the genome. Although i
Externí odkaz:
https://doaj.org/article/693bd8e673be46a79c89da26efca485f
Autor:
Jacqueline K. Dawson PhD, Tanya B. Dorff MD, Creighton Tuzon PhD, Judd C. Rice PhD, Edward Todd Schroeder PhD, Christianne J. Lane PhD, Mitchell E. Gross MD, PhD, Christina M. Dieli-Conwright PhD
Publikováno v:
Integrative Cancer Therapies, Vol 20 (2021)
Purpose: Prostate cancer survivors (PCS) receive androgen deprivation therapy (ADT) as treatment for recurrent cancer, yet ADT is associated with loss of skeletal muscle and physical function. Resistance training can counter both muscle and physical
Externí odkaz:
https://doaj.org/article/4392a449cef04be9945610b2a4046d19
Autor:
Creighton T. Tuzon, Tanya Spektor, Xiaodong Kong, Lauren M. Congdon, Shumin Wu, Gunnar Schotta, Kyoko Yokomori, Judd C. Rice
Publikováno v:
Cell Reports, Vol 8, Iss 2, Pp 430-438 (2014)
Although selective binding of 53BP1 to dimethylated histone H4 lysine 20 (H4K20me2) at DNA double-strand breaks (DSBs) is a necessary and pivotal determinant of nonhomologous end joining (NHEJ)-directed repair, the enzymes that generate H4K20me2 at D
Externí odkaz:
https://doaj.org/article/ec95bf93338f4bc69b65aa395da18533
Autor:
Zhihui Chen, Zea Borok, Sun Young Lee, Benjamin H. Weekley, Judd C. Rice, Daniel J. Fernandez, Alessandra Castaldi, Rachel Abrahamson, Tomas Kanholm, Woojin An, Brian David Dynlacht
Publikováno v:
Epigenetics & Chromatin
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-12 (2021)
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-12 (2021)
BackgroundSelective proteolysis of the histone H3 N-terminal tail (H3NT) is frequently observed during eukaryotic development, generating a cleaved histone H3 (H3cl) product within a small, but significant, portion of the genome. Although increasing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237b9ef3af1593eff33ba25a1a752b03
https://pubmed.ncbi.nlm.nih.gov/34001241
https://pubmed.ncbi.nlm.nih.gov/34001241
Autor:
Gary G. Chiang, Masoud Vedadi, Alberto Martin, Dalia Barsyte-Lovejoy, William N. Pappano, Cheryl H. Arrowsmith, Alexander Nuber, Vijayaratnam Santhakumar, Kenneth M. Comess, Judd C. Rice, Maricel Torrent, Gunnar Schotta, Peter Brown, Conglei Li, Anup K. Upadhyay, Fengling Li, Alex R Shoemaker, Ramzi F. Sweis, Mikkel Algire, Yujia Dai, Loren M. Lasko, Taylor R H Mitchell, Creighton T. Tuzon, Kenneth D. Bromberg, Mohammad S. Eram, Michael R. Michaelides, Niru B. Soni, Clarissa G. Jakob, Chaohong Sun, Manisha A Jhala, Vlasios Manaves
Publikováno v:
Nature Chemical Biology. 13:317-324
Protein lysine methyltransferases (PKMTs) regulate diverse physiological processes including transcription and the maintenance of genomic integrity. Genetic studies suggest that the PKMTs SUV420H1 and SUV420H2 facilitate proficient nonhomologous end-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa83d9f95eebf4a7288c158fbe1c7aaf
https://doi.org/10.1038/nchembio.2282
https://doi.org/10.1038/nchembio.2282
Autor:
Vasu Punj, Sun Young Lee, Woojin An, Wange Lu, Judd C. Rice, Tobias S. Ulmer, Kyunghwan Kim, Jin-Man Kim
Publikováno v:
Genes & Development. 30:208-219
Although limited proteolysis of the histone H3 N-terminal tail (H3NT) is frequently observed during mammalian differentiation, the specific genomic sites targeted for H3NT proteolysis and the functional significance of H3NT cleavage remain largely un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2520632767c589230dd9f43aba4fe535
https://doi.org/10.1101/gad.268714.115
https://doi.org/10.1101/gad.268714.115
Autor:
Thomas Schmidt, Judd C. Rice, Tobias S. Ulmer, Jin-Man Kim, Haley O. Tucker, Kyunghwan Kim, Woojin An, Vasu Punj
Publikováno v:
Nucleic Acids Research
SET and MYND domain containing protein 3 (SMYD3) is a histone methyltransferase, which has been implicated in cell growth and cancer pathogenesis. Increasing evidence suggests that SMYD3 can influence distinct oncogenic processes by acting as a gene-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f975e3006c24e45d0416899d628d37e3
https://doi.org/10.1093/nar/gkv874
https://doi.org/10.1093/nar/gkv874
Autor:
George J. Salem, Christianne J. Lane, Tanya B. Dorff, Judd C. Rice, Mitchell E. Gross, E. Todd Schroeder, Jacqueline L. Kiwata, Christina M. Dieli-Conwright
Publikováno v:
BMJ Open
Introduction Prostate cancer survivors (PCS) receiving androgen deprivation therapy (ADT) experience deleterious side effects such as unfavourable changes in cardiometabolic factors that lead to sarcopenic obesity and metabolic syndrome (MetS). While
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbc721d1cfeda59aa07825a3dd34c9c
https://pubmed.ncbi.nlm.nih.gov/28698349
https://pubmed.ncbi.nlm.nih.gov/28698349
Autor:
Judd C. Rice, Lauren M. Congdon, Kyoko Yokomori, Xiaodong Kong, Gunnar Schotta, Shumin Wu, Creighton T. Tuzon, Tanya M. Spektor
Publikováno v:
Cell Reports, Vol 8, Iss 2, Pp 430-438 (2014)
Cell reports, vol 8, iss 2
Tuzon, CT; Spektor, T; Kong, X; Congdon, LM; Wu, S; Schotta, G; et al.(2014). Concerted Activities of Distinct H4K20 Methyltransferases at DNA Double-Strand Breaks Regulate 53BP1 Nucleation and NHEJ-Directed Repair. Cell Reports, 8(2), 430-438. doi: 10.1016/j.celrep.2014.06.013. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8j4860p6
Cell reports, vol 8, iss 2
Tuzon, CT; Spektor, T; Kong, X; Congdon, LM; Wu, S; Schotta, G; et al.(2014). Concerted Activities of Distinct H4K20 Methyltransferases at DNA Double-Strand Breaks Regulate 53BP1 Nucleation and NHEJ-Directed Repair. Cell Reports, 8(2), 430-438. doi: 10.1016/j.celrep.2014.06.013. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8j4860p6
Although selective binding of 53BP1 to dimethylated histone H4 lysine 20 (H4K20me2) at DNA double-strand breaks (DSBs) is a necessary and pivotal determinant of nonhomologous end joining (NHEJ)-directed repair, the enzymes that generate H4K20me2 at D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817f63953652abdbf9c40c4cef5ca962
http://www.sciencedirect.com/science/article/pii/S2211124714004811
http://www.sciencedirect.com/science/article/pii/S2211124714004811