Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Judah I. Rosenblatt"'
Autor:
Judah I. Rosenblatt, Jeffrey K. Wickliffe, Jonathan B. Ward, Curtis J. Omiecinski, Marinel M. Ammenheuser, Sherif Z. Abdel-Rahman
Publikováno v:
Toxicological Sciences. 85:624-631
The carcinogenic effects of 1,3-butadiene (BD), a mutagenic chemical widely used in the manufacture of synthetic rubber, are likely initiated through its epoxide metabolites. In humans, these epoxides are detoxified predominantly by hydrolysis, a rea
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 29:8-11
Autor:
Darlene A. Hastings-Smith, Jonathan B. Ward, Judah I. Rosenblatt, Sherif Z. Abdel-Rahman, Marinel M. Ammenheuser, William E. Bechtold
Publikováno v:
Environmental Health Perspectives
1,3-Butadiene (BD), which is used to make styrene-butadiene rubber, is a potent carcinogen in mice and a probable carcinogen, associated with leukemia, in humans. We have previously used HPRT mutation as a biomarker to evaluate exposures to BD in a m
Publikováno v:
Environmental and Molecular Mutagenesis. 36:59-71
1,3-Butadiene (BD) has been shown to be a potent animal carcinogen and a probable human carcinogen, yet the molecular mechanisms of BD genotoxicity and carcinogenicity still are not fully understood. Our hypothesis is that metabolites of BD induce sp
Publikováno v:
Cytometry. 36:60-70
Background: As flow cytometric data becomes more complex, it becomes increasingly difficult to classify cells using conventional flow cytometry data techniques based on visual classification of the data by user-drawn regions. This paper shows some si
Publikováno v:
The Journal of Hand Surgery. 23:446-453
Carpal kinematics during a wrist flexion/extension motion using high-speed videodata acquisition was investigated. A cadaver forearm was stabilized, allowing unconstrained excursion of the wrist for passive range of motion (ROM). The extensor and fle
Publikováno v:
Cytometry. 27:233-238
This paper describes new approaches to calculating the number of cells that need to be processed using flow cytometry (FCM) techniques and the subsequent time required in order to isolate a specific number of cells having selected characteristics. Th
Publikováno v:
Hand Clinics. 13:129-141
The purpose of this study was to evaluate the effect that external fixation devices used for distal radius fractures have on normal carpal kinematics, using high speed video data acquisition. Cadaver forearms were stabilized, allowing free excursion
Publikováno v:
Mutation Research/DNA Repair. 363:57-66
Methods for measuring the induction and repair of ultraviolet (UV) induced modifications in short DNA fragments are essential for the study of gene-specific DNA repair. Measurements in genomic fragments of 14 kilobases (kb) or larger can be obtained
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 263:E584-E596
In metabolic tracer studies it is frequently useful to infuse tracers that are differently labeled variants of the same molecule. These tracers are known as isotopomers. Analysis of the enrichment of each isotopic analogue can be accomplished by gas