Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Jucimara Colombo"'
1
Akademický článek
Modulation of Epithelial Mesenchymal Transition after AGTR-1 Gene Edition by Crispr/Cas9 and Losartan Treatment in Mammary Tumor Cell Line: A Comparative Study between Human and Canine Species
Autor: Marina Gobbe Moschetta-Pinheiro, Jucimara Colombo, Bianca Lara Venâncio de Godoy, Julia Ferreira Balan, Bianca Carlos Nascimento, Debora Aparecida Pires de Campos Zuccari
Publikováno v: Life, Vol 11, Iss 12, p 1427 (2021)
Breast cancer is the most prevalent tumor type among women and female dogs. Tumor malignancy is characterized by the epithelial-to-mesenchymal transition (EMT) which leads to the metastasis formation. The inhibition of angiotensin II type I receptor
Externí odkaz: https://doaj.org/article/9279a990f24d43bd920d24a7c1d5bfff
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2
Akademický článek
Effect of Melatonin in Epithelial Mesenchymal Transition Markers and Invasive Properties of Breast Cancer Stem Cells of Canine and Human Cell Lines.
Autor: Naiane do Nascimento Gonçalves, Jucimara Colombo, Juliana Ramos Lopes, Gabriela Bottaro Gelaleti, Marina Gobbe Moschetta, Nathália Martins Sonehara, Eva Hellmén, Caroline de Freitas Zanon, Sônia Maria Oliani, Debora Aparecida Pires de Campos Zuccari
Publikováno v: PLoS ONE, Vol 11, Iss 3, p e0150407 (2016)
Cancer stem cells (CSCs) have been associated with metastasis and therapeutic resistance and can be generated via epithelial mesenchymal transition (EMT). Some studies suggest that the hormone melatonin acts in CSCs and may participate in the inhibit
Externí odkaz: https://doaj.org/article/7f2ce1267bc74bebb699e483d3255a0e
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3
Akademický článek
Polymorphisms of the DNA repair genes XRCC1 and XRCC3 in a Brazilian population
Autor: Márcia Cristina Duarte, Jucimara Colombo, Andréa Regina Baptista Rossit, Ana Elizabete Silva
Publikováno v: Genetics and Molecular Biology, Vol 28, Iss 3, Pp 397-401 (2005)
In several DNA repair genes, polymorphisms may result in reduced repair capacity, which has been implicated as a risk factor for various types of cancer. The frequency of the polymorphic alleles varies among populations, suggesting an ethnic distribu
Externí odkaz: https://doaj.org/article/8f943786e0c94c298ec79365c438db8e
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4
Akademický článek
Alterações Genéticas em Câncer de Cabeça e Pescoço
Autor: Jucimara Colombo, Paula Rahal
Publikováno v: Revista Brasileira de Cancerologia, Vol 55, Iss 2 (2009)
O carcinoma de células escamosas de cabeça e pescoço (HNSCC) constitui o quinto tipo de câncer mais comum mundialmente, com uma incidência anual global de 780.000 novos casos. Os sítios comuns incluem cavidade oral, orofaringe, hipofaringe, nas
Externí odkaz: https://doaj.org/article/cb59e64b4f5247b8a7640db1ba6243b8
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7
Verification of agomelatine in comparison with melatonin as a therapeutic agent to treat breast cancer
Autor: Amabile Oficiati de Carnevale Galeti, Jessica Gisleine de Oliveira, Jucimara Colombo, Marina Gobbe Moschetta Pinheiro, Mariana Bastos dos Santos, Debora Aparecida Pires de Campos Zuccari, Luiz Gustavo de Almeida Chuffa
Publikováno v: Melatonin Research. 4:141-151
The breast cancer (BC) has a high rate of morbidity and mortality; thus, the discovery of new therapeutic targets is of great interest for researchers. Previous studies have documented that melatonin, the main hormone synthesized by the pineal gland,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe629f0821e0e1af6e23bac8c4329243
https://doi.org/10.32794/mr11250087
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8
Melatonin Treatment Combined with TGF-β Silencing Inhibits Epithelial- Mesenchymal Transition in CF41 Canine Mammary Cancer Cell Line
Autor: Jucimara Colombo, Paulo R Custódio, Debora Aparecida Pires de Campos Zuccari, Tialfi Bergamin de Castro, Fabrício V Ventura
Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2020-12-12T02:17:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Background: Mammary cancer is the most prevalent type of cancer in female d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f49a871b9eebc53d4c929a4addf143
https://doi.org/10.2174/1871520620666200407122635
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9
Melatonin modifies tumor hypoxia and metabolism by inhibiting HIF-1α and energy metabolic pathway in the in vitro and in vivo models of breast cancer
Autor: Vinícius Augusto Gonçalves Pierri, Nathália Martins Sonehara, Bruna Vitorasso Jardim-Perassi, Debora Aparecida Pires de Campos Zuccari, Victor Keniti Gomes Nishiyama, Jucimara Colombo, André de Lima Mota, Tialfi Bergamin de Castro
Publikováno v: Melatonin Research. 2:83-98
Breast cancer is the most common cancer among women and has a high mortality rate. Adverse conditions in the tumor microenvironment, such as hypoxia and acidosis, may exert selective pressure on the tumor, selecting subpopulations of tumor cells with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ebd8411d0b5791b02af749c74638715f
https://doi.org/10.32794/mr11250042
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10
Liquid biopsy can detect BRCA2 gene variants in female dogs with mammary neoplasia
Autor: Marina Gobbe Moscheta-Pinheiro, Aureo Evangelista Santana, Luiz Lehmann Coutinho, Francine Moraes Gonçalves, Debora Aparecida Pires de Campos Zuccari, Adriana Alonso Novais, Luiz Gustavo de Almeida Chuffa, Jéssica Rodrigues de Oliveira, Lucas Amoroso Lopes de Carvalho, Douglas Santos Costa, Tiago Henrique, Jucimara Colombo
Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Made available in DSpace on 2022-04-29T08:33:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Mammary tumours (MT) are one of the most prevalent malignancies in female d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd2b85cb2f6adf70d26576a6a293e19
https://pubmed.ncbi.nlm.nih.gov/34328705
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