Zobrazeno 1 - 10
of 2 013
pro vyhledávání: '"Juby"'
Autor:
Nandini Pal Basak, Kowshik Jaganathan, Biswajit Das, Oliyarasi Muthusamy, Rajashekar M, Ritu Malhotra, Amit Samal, Moumita Nath, Ganesh MS, Amritha Prabha Shankar, Prakash BV, Vijay Pillai, Manjula BV, Jayaprakash C, Vasanth K, Gowri Shankar K, Sindhu Govindan, Syamkumar V, Juby, Koushika R, Chandan Bhowal, Upendra Kumar, Govindaraj K, Mohit Malhotra, Satish Sankaran
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Dynamic interactions within the tumor micro-environment drive patient response to immune checkpoint inhibitors. Existing preclinical models lack true representation of this complexity. Using a Head and Neck cancer patient derived TruTumor hi
Externí odkaz:
https://doaj.org/article/9dbb8fcc65214595a787b6c11342d00b
Autor:
Claus Bachert, Alexandra Hicks, Simon Gane, Anju T. Peters, Philippe Gevaert, Scott Nash, Julie E. Horowitz, Harry Sacks, Juby A. Jacob-Nara
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Chronic rhinosinusitis with nasal polyps (CRSwNP) is predominantly a type 2 inflammatory disease associated with type 2 (T2) cell responses and epithelial barrier, mucociliary, and olfactory dysfunction. The inflammatory cytokines interleukin (IL)-4,
Externí odkaz:
https://doaj.org/article/07680387bb2f4661b246cb0f136e66af
Autor:
Wytske J Fokkens, Claus Bachert, Claire Hopkins, Osama Marglani, Amy Praestgaard, Scott Nash, Yamo Deniz, Paul J Rowe, Harry Sacks, Juby A Jacob‐Nara
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 6, Pp n/a-n/a (2024)
Abstract Objectives This post hoc analysis assessed disease characteristics and response to dupilumab treatment in male and female patients with severe chronic rhinosinusitis with nasal polyps (CRSwNP) (SINUS‐52 study; NCT02898454). Methods Patient
Externí odkaz:
https://doaj.org/article/cfa966c8d76542fe808ba1868727c8f7
Autor:
Christian Domingo, Klaus F. Rabe, David Price, Guy Brusselle, Michael E. Wechsler, Changming Xia, Nami Pandit-Abid, Rebecca Gall, Paul J. Rowe, Yamo Deniz, Juby A. Jacob-Nara, Amr Radwan
Publikováno v:
ERJ Open Research, Vol 9, Iss 6 (2023)
Background Dupilumab has been shown to improve clinical outcomes long term while reducing oral corticosteroid (OCS) dose in patients with severe OCS-dependent asthma. This post hoc analysis assesses the impact of OCS dose at baseline (≤10 or >10 mg
Externí odkaz:
https://doaj.org/article/4cc17fdbebce48e9b57861c1623c47cb
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 356 (2024)
In the field of preparing cosmetic formulations, recent advances recommend the usage of excipients derived from biocompatible materials. In this context, the present study aimed to prepare and characterize the curcumin-loaded Pickering emulsion for p
Externí odkaz:
https://doaj.org/article/05c7a8c5f8df482fbea97908020cf91e
Autor:
Jonathan Corren, Constance H. Katelaris, Mario Castro, Jorge F. Maspero, Marc Humbert, David M.G. Halpin, Arman Altincatal, Nami Pandit-Abid, Xavier Soler, Amr Radwan, Juby A. Jacob-Nara, Yamo Deniz, Paul J. Rowe
Publikováno v:
ERJ Open Research, Vol 9, Iss 5 (2023)
Background The phase 3 QUEST (NCT02414854) and TRAVERSE (NCT02134028) studies demonstrated the efficacy of dupilumab 200/300 mg versus placebo every 2 weeks for 52 weeks (QUEST) and dupilumab 300 mg up to an additional 96 weeks (TRAVERSE) in patients
Externí odkaz:
https://doaj.org/article/5dd99f3023aa41019700fab408bfb6d4
Autor:
Yuji Tohda, Yoichi Nakamura, Takao Fujisawa, Motohiro Ebisawa, Jerome Msihid, Michel Djandji, Benjamin Ortiz, Juby A. Jacob-Nara, Yamo Deniz, Paul J. Rowe, Masato Ishida, Kazuhiko Arima
Publikováno v:
Allergology International, Vol 72, Iss 1, Pp 89-99 (2023)
Background: Safety and efficacy data for dupilumab beyond 1 year are lacking for patients from Japan with moderate-to-severe asthma. Methods: The TRAVERSE open-label extension (OLE) study (NCT02134028) assessed the safety and efficacy of dupilumab 30
Externí odkaz:
https://doaj.org/article/a6454e7b2c504233a7b1ee0de552fd38
Autor:
Lucia De Prado Gomez, Ian Pavord, William Busse, Christopher E. Brightling, Michael E. Wechsler, Klaus F. Rabe, Mei Zhang, Jun Xing, Juby A. Jacob-Nara, Paul J. Rowe
Publikováno v:
ERJ Open Research, Vol 9, Iss 2 (2023)
Background Many patients with asthma experience loss of lung function over time, and in certain patients this can lead to progressive obstructive patterns similar to COPD. Patients with severe asthma may experience accelerated lung function decline (
Externí odkaz:
https://doaj.org/article/29665b18d99e4e989031208479d20f81
Publikováno v:
Current Medicine Research and Practice, Vol 12, Iss 3, Pp 100-105 (2022)
Objective: Suicide is an unrecognised and underestimated epidemic of high complexity and accounts for premature loss of at least 1 million lives worldwide, leaving behind irreparable loss and backlash to family, friends and society. This study was ca
Externí odkaz:
https://doaj.org/article/c0c34b02118e4d06892315553e12634b
Publikováno v:
Journal of Veterinary and Animal Sciences, Vol 53, Iss 1, Pp 39-43 (2022)
Pigeon rearing is comparatively easy and profitable when compared to rearing of otherexotic birds such as canaries and parrots. As the bird population is on the rise, there is a steady upsurge in the occurrence of diseases too. Parasitic infestation
Externí odkaz:
https://doaj.org/article/18d2eda445b94002b80124e52af5bfaf