Antenatal Hypoxia and Programming of Glucocorticoid Receptor Expression in the Adult Rat Heart

Autor: Juanxiu Lv, Qingyi Ma, Chiranjib Dasgupta, Zhice Xu, Lubo Zhang

Publikováno v: Frontiers in Physiology, Vol 10 (2019)

Glucocorticoid receptor (GR) signaling is critical for development and function of the heart. Our previous study demonstrated that gestational hypoxia induced epigenetic repression of the GR gene in the developing heart. The present study aims to det

Externí odkaz: https://doaj.org/article/c35335fccccf4192ab580f4ff79f88f7

In utero hypoxia altered Ang II-induced contraction via PKCβ in fetal cerebral arteries

Autor: Linglu Qi, Jiaqi Tang, Zhice Xu, Xiang Li, Hongyu Su, Xueyi Chen, Juanxiu Lv, Yingying Zhang, Yun He, Yueming Zhang

Publikováno v: Journal of Endocrinology. 244:213-222

Cerebral circulation is important in fetal brain development, and angiotensin II (Ang II) plays vital roles in regulation of adult cerebral circulation. However, functions of Ang II in fetal cerebral vasculature and influences of in utero hypoxia on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4da8f5e1541b6d6436a6089fa8c4752
https://doi.org/10.1530/joe-19-0370

Neonatal Lipopolysaccharide Exposure Gender-Dependently Increases Heart Susceptibility to Ischemia/Reperfusion Injury in Male Rats

Autor: Lubo Zhang, Daliao Xiao, Yong Li, Juanxiu Lv, Peng Zhang

Publikováno v: Zhang, P; Lv, J; Li, Y; Zhang, L; & Xiao, DL. (2017). Neonatal lipopolysaccharide exposure gender-dependently increases heart susceptibility to ischemia/reperfusion injury in male rats. International Journal of Medical Sciences, 14(11), 1163-1172. doi: 10.7150/ijms.20285. UC Office of the President: Tobacco-Related Disease Research Program. Retrieved from: http://www.escholarship.org/uc/item/2dp393qc
International journal of medical sciences, vol 14, iss 11
International Journal of Medical Sciences

© Ivyspring International Publisher. Background: Adverse stress exposure during the early neonatal period has been shown to cause aberrant development, resulting in an increased risk of adult disease. We tested the hypothesis that neonatal exposure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239acc122e44a0d80e069c01c295ee10
https://doi.org/10.7150/ijms.20285

Disrupting the circadian photo-period alters the release of follicle-stimulating hormone, luteinizing hormone, progesterone, and estradiol in maternal and fetal sheep

Autor: Pengjie Zhang, Qinqin Gao, Juanxiu Lv, Jianying Tao, Weisheng Li, Zhice Xu

Publikováno v: The Journal of Reproduction and Development

Although a large number of studies show that photo-period disruption potentially affects hormone secretion in mammals, information about the effects of circadian photo-period disruption during pregnancy on fetal blood reproductive hormone levels is s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5c2fe79400873a26d387734287dd55
https://doi.org/10.1262/jrd.2016-009

Prenatal High‐Salt Diet–Induced Metabolic Disorders via Decreasing Peroxisome Proliferator–Activated Receptor Gamma Coactivator 1α in Adult Male Rat Offspring

Autor: Phung N. Thai, Juanxiu Lv, Zhice Xu, Lubo Zhang, Miao Sun, Yanping Liu, Dan Zhu, Linglu Qi, Yingying Zhang, Chunli Yang, Xiyuan Lu, Xueqin Feng, Jun Guo, Pengjie Zhang

Publikováno v: Molecular Nutrition & Food Research. 64:2000196

Scope Although prenatal high-salt (HS) intake leads to physiological complications in the offspring, little is known regarding its effects on the offspring's glucose metabolism. Therefore, the objectives of this study are to determine the consequence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb97285e699edf25721daa10b79ad249
https://doi.org/10.1002/mnfr.202000196