Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Juanxia Meng"'
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTChimeric antigen receptor (CAR)-T cells have not made significant progress in the treatment of acute myeloid leukemia (AML) in earlyclinical studies. This lack of progress could be attributed in part to the immunosuppressive microenvironment
Externí odkaz:
https://doaj.org/article/ce21bdd2d62c4e0f8d350aaa3c4c612f
Autor:
Jiaxi Wang, Meng Zhang, Hairong Lyu, Ruiting Guo, Xia Xiao, Xue Bai, Yedi Pu, Juanxia Meng, Qing Li, Ting Yuan, Wenyi Lu, Mingfeng Zhao
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionHematologic toxicity (HT) is a joint adverse event after CAR-T cells infusion. Some patients experience prolonged hematologic toxicity (PHT), which is challenging to treat.MethodsWe collected clinical data from patients with relapsed refr
Externí odkaz:
https://doaj.org/article/cc52c3e7650f435f94c46230772cda24
Autor:
Wenyi Lu, Xin Jin, Hairong Lyu, Xue Bai, Haibo Zhu, Xin Li, Xia Xiao, Juanxia Meng, Ting Yuan, Qing Li, Juan Mu, Cuicui Lyu, Yili Jiang, Yunxiong Wei, Xia Xiong, Meng Zhang, Mingfeng Zhao
Publikováno v:
Cell Transplantation, Vol 31 (2022)
Although haploidentical donor (HID) hematopoietic stem cell transplantation (HSCT) has achieved similar survival to HLA-identical sibling donor (ISD) transplantation, the delayed hematopoietic engraftment as well as higher incidence of graft-versus-h
Externí odkaz:
https://doaj.org/article/664e4898a8ea418392dd2882588ac627
Autor:
Xin Jin, Xiaoyuan He, Xiaoli Cao, Ping Xu, Yi Xing, Songnan Sui, Luqiao Wang, Juanxia Meng, Wenyi Lu, Rui Cui, Hongyan Ni, Mingfeng Zhao
Publikováno v:
Haematologica, Vol 103, Iss 10 (2018)
There is increasing clinical evidence to suggest a suppressive effect on hematopoiesis in myelodysplastic syndrome patients with iron overload. However, how iron overload influences hematopoiesis in myelodysplastic syndrome (MDS) remains unknown. Her
Externí odkaz:
https://doaj.org/article/33a8566240ed410db260b5ffb67133bf
Autor:
Yuchen Zhang, Wenjing Zhai, Mingfeng Zhao, Deguan Li, Xiao Chai, Xiaoli Cao, Juanxia Meng, Jie Chen, Xia Xiao, Qing Li, Juan Mu, Jichun Shen, Aimin Meng
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120219 (2015)
Using a mouse model, Iron Overload (IO) induced bone marrow microenvironment injury was investigated, focusing on the involvement of reactive oxygen species (ROS).Mice were intraperitoneally injected with iron dextran (12.5, 25, or 50 mg) every three
Externí odkaz:
https://doaj.org/article/b535b29411544170bc0e72058ac08b6f
Autor:
Xiaoyuan He, Mingfeng Zhao, Jinyan Chen, Rimao Wu, Jianlei Zhang, Rui Cui, Yanyu Jiang, Jie Chen, Xiaoli Cao, Yi Xing, Yuchen Zhang, Juanxia Meng, Qi Deng, Tao Sui
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136185 (2015)
To study the main molecular mechanisms responsible for itraconazole resistance in clinical isolates of Candida krusei.The 14α-demethylases encoded by ERG11 gene in the 16 C.krusei clinical isolates were amplified by polymerase chain reaction (PCR),
Externí odkaz:
https://doaj.org/article/9755ec3ca4474d64a92c8b9f3ccde579
Autor:
Meng, Zhang, Wenyi, Lu, Danni, Xie, Jiaxi, Wang, Xia, Xiao, Yedi, Pu, Juanxia, Meng, Hairong, Lyu, Mingfeng, Zhao
Publikováno v:
Infection and Drug Resistance. 15:7509-7517
Meng Zhang,1,* Wenyi Lu,2,* Danni Xie,1 Jiaxi Wang,1 Xia Xiao,2 Yedi Pu,2 Juanxia Meng,2 Hairong Lyu,2 Mingfeng Zhao2 1First Center Clinic College of Tianjin Medical University, Tianjin, 300192, Peopleâs Republic of China; 2Department of
Publikováno v:
Leukemia & Lymphoma. 63:353-361
Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy has led to unprecedented results to date in relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL), yet its clinical application in elderly patients with R/R DLBCL remains somewhat lim
Autor:
Meng Zhang, Zhao Wang, Jiaxi Wang, Hairong Lv, Xia Xiao, Wenyi Lu, Xin Jin, Juanxia Meng, Yedi Pu, MingFeng Zhao
Publikováno v:
Infection and drug resistance. 15
Meng Zhang,1,2,* Zhao Wang,2,* Jiaxi Wang,1 Hairong Lv,2 Xia Xiao,2 Wenyi Lu,2 Xin Jin,2 Juanxia Meng,2 Yedi Pu,2 MingFeng Zhao2 1First Central Clinical College, Tianjin Medical University, Tianjin, 300192, Peopleâs Republic of China; 2D
Publikováno v:
British Journal of Haematology
Summary We studied the efficacy and safety of humanized CAR‐T therapy following intensive chemotherapy for refractory/relapsed (R/R) acute lymphoblastic leukaemia (B‐ALL). Twenty‐three patients with R/R B‐ALL were pretreated with intensive ch