Validation of preimplantation genetic tests for aneuploidy (PGT-A) with DNA from spent culture media (SCM): concordance assessment and implication

Autor: Baoli Yin, Huijuan Zhang, Juanke Xie, Yubao Wei, Cuilian Zhang, Li Meng

Publikováno v: Reproductive Biology and Endocrinology, Vol 19, Iss 1, Pp 1-12 (2021)

Abstract Background Spent culture medium (SCM) as a source of DNA for preimplantation genetic tests aneuploidy (PGT-A) has been widely discussed. Methods Seventy-five blastocysts that were donated for research provided a unique possibility in which m

Externí odkaz: https://doaj.org/article/53c5bbd116724e908418c6880ece6ddc

Validation of preimplantation genetic tests for aneuploidy (PGT-A) with DNA from spent culture media (SCM): concordance assessment and implication

Autor: Baoli Yin, Huijuan Zhang, Juanke Xie, Yaxin Yao, Yubao Wei, Cuilian Zhang, Li Meng

Background: Spent culture medium (SCM) as a source of DNA for preimplantation genetic tests aneuploidy (PGT-A) has been widely discussed. Methods: Seventy-five blastocysts donated for research provided a unique possibility in which multiple specimens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc7f08146e9aa6ebeccdce74b8bac6dc
https://doi.org/10.21203/rs.3.rs-110130/v1

Significantly lengthened telomere in granulosa cells from women with polycystic ovarian syndrome (PCOS)

Autor: Juanke Xie, Baoli Yin, Qi Liu, Haoying Hao, Xiaobing Song, Cuilian Zhang, Yingpu Sun, Duo Wei

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy among women at reproductive age. However, its etiology remains poorly understood. Recent studies indicated that telomere length was related to PCOS. However, the association between t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553e0db76ae2305674f0a46f2a410df2
https://europepmc.org/articles/PMC5476553/

H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase

Autor: Hugh S. Taylor, Gordon G. Carmichael, Hunter Chung, Lihua Yang, Tianyu Zhong, Xueguang Sun, Martin Mueller, Lingeng Lu, Karolyn Giang, Juanke Xie, Yi Men, Jichun Zhou, Yingqun Huang, Na Zhang

Publikováno v: Zhou, Jichun; Yang, Lihua; Zhong, Tianyu; Müller, Martin; Men, Yi; Zhang, Na; Xie, Juanke; Giang, Karolyn; Chung, Hunter; Sun, Xueguang; Lu, Lingeng; Carmichael, Gordon G; Taylor, Hugh S; Huang, Yingqun (2015). H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase. Nature communications, 6, p. 10221. Nature Publishing Group 10.1038/ncomms10221
Nature Communications

DNA methylation is essential for mammalian development and physiology. Here we report that the developmentally regulated H19 lncRNA binds to and inhibits S-adenosylhomocysteine hydrolase (SAHH), the only mammalian enzyme capable of hydrolysing S-aden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24502ad8170ff5be8b9d17d93c5ca773
https://doi.org/10.1038/ncomms10221

Patients with polycystic ovary syndrome have successful embryo arrest

Autor: Baoli, Yin, Haoying, Hao, Duo, Wei, Xiaobing, Song, Juanke, Xie, Cuilian, Zhang

Publikováno v: International journal of clinical and experimental medicine. 8(4)

In this retrospective study, we investigate the relationship between embryo arrest and polycystic ovary syndrome (PCOS) during in vitro fertilization-embryo transfer (IVF-ET). In this study, 667 subjects were enrolled, including 330 patients with PCO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9c5f377602d3e2d642ec8d5e099bae06
https://pubmed.ncbi.nlm.nih.gov/26131233