Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Juanjie, Tang"'
Autor:
Dapeng Li, David R. Martinez, Alexandra Schäfer, Haiyan Chen, Maggie Barr, Laura L. Sutherland, Esther Lee, Robert Parks, Dieter Mielke, Whitney Edwards, Amanda Newman, Kevin W. Bock, Mahnaz Minai, Bianca M. Nagata, Matthew Gagne, Daniel C. Douek, C. Todd DeMarco, Thomas N. Denny, Thomas H. Oguin, Alecia Brown, Wes Rountree, Yunfei Wang, Katayoun Mansouri, Robert J. Edwards, Guido Ferrari, Gregory D. Sempowski, Amanda Eaton, Juanjie Tang, Derek W. Cain, Sampa Santra, Norbert Pardi, Drew Weissman, Mark A. Tomai, Christopher B. Fox, Ian N. Moore, Hanne Andersen, Mark G. Lewis, Hana Golding, Robert Seder, Surender Khurana, Ralph S. Baric, David C. Montefiori, Kevin O. Saunders, Barton F. Haynes
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The authors have previously demonstrated the neutralising capacity of their nanoparticle vaccine, as well as showing protection of non-human primates from SARS-CoV-2 WA-1 infection. In this work, they investigate the ability of their vaccine candidat
Externí odkaz:
https://doaj.org/article/b08586c46f7c4fa6b00bfd070a9caed1
Autor:
Juanjie Tang, Tanya Novak, Julian Hecker, Gabrielle Grubbs, Fatema Tuz Zahra, Lorenza Bellusci, Sara Pourhashemi, Janet Chou, Kristin Moffitt, Natasha B. Halasa, Stephanie P. Schwartz, Tracie C. Walker, Keiko M. Tarquinio, Matt S. Zinter, Mary A. Staat, Shira J. Gertz, Natalie Z. Cvijanovich, Jennifer E. Schuster, Laura L. Loftis, Bria M. Coates, Elizabeth H. Mack, Katherine Irby, Julie C. Fitzgerald, Courtney M. Rowan, Michele Kong, Heidi R. Flori, Aline B. Maddux, Steven L. Shein, Hillary Crandall, Janet R. Hume, Charlotte V. Hobbs, Adriana H. Tremoulet, Chisato Shimizu, Jane C. Burns, Sabrina R. Chen, Hye Kyung Moon, Christoph Lange, Adrienne G. Randolph, Surender Khurana
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
The antibody response to the SARS-CoV-2 Omicron variant is not well studied in children. Here, the authors provide an age-stratified analysis of SARS-CoV-2 neutralizing capacity of sera from children with acute or convalescent COVID-19 as well as chi
Externí odkaz:
https://doaj.org/article/e95d32cb646c4ee9abe90f1a0721b0aa
Autor:
Jeehyun Lee, Youri Lee, Laura Klenow, Elizabeth M Coyle, Juanjie Tang, Supriya Ravichandran, Hana Golding, Surender Khurana
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 1, Pp 1-14 (2021)
Abstract Respiratory syncytial virus (RSV) vaccines primarily focused on surface fusion (F) protein are under development. Therefore, to identify RSV‐F protective epitopes, we evaluated 14 antigenic sites recognized following primary human RSV infe
Externí odkaz:
https://doaj.org/article/d081e38e0a3944c7b14e4acc86657600
Autor:
Juanjie Tang, Supriya Ravichandran, Youri Lee, Gabrielle Grubbs, Elizabeth M. Coyle, Laura Klenow, Hollie Genser, Hana Golding, Surender Khurana
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
SARS-CoV2 infection has been linked to a wide range of clinical severities and the immunopathology is still under intense scrutiny. Here, the authors uncover an association of antibody affinity maturation and plasma IgA levels with clinical outcome i
Externí odkaz:
https://doaj.org/article/31cff301b7dd4bd78c29bf2e37eef897
Autor:
Yun-Jong Park, David Acosta, Russell Vassell, Juanjie Tang, Surender Khurana, Carol D Weiss, Hana Golding, Marina Zaitseva
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010468 (2022)
An overreactive inflammatory response and coagulopathy are observed in patients with severe form of COVID-19. Since increased levels of D-dimer (DD) are associated with coagulopathy in COVID-19, we explored whether DD contributes to the aberrant cyto
Externí odkaz:
https://doaj.org/article/2c155b1c36614a3b86a73c32ae5535c1
Autor:
Youri Lee, Gabrielle Grubbs, Sabrina C. Ramelli, Andrea R. Levine, Allison Bathula, Kapil Saharia, Madeleine Purcell, Shreya Singireddy, Colleen L. Dugan, Lindsey Kirchoff, Allison Lankford, Sarah Cipriano, Ryan A. Curto, Jocelyn Wu, Katherine Raja, Emily Kelley, Daniel Herr, Kevin M. Vannella, Supriya Ravichandran, Juanjie Tang, Anthony Harris, Mohammad Sajadi, Daniel S. Chertow, Alison Grazioli, Surender Khurana
Publikováno v:
EBioMedicine, Vol 77, Iss , Pp 103940- (2022)
Summary: Background: Limited knowledge exists in post-partum women regarding durability of SARS-CoV-2 vaccine-induced antibody responses and their neutralising ability against SARS-CoV-2 variants of concern (VOC). Methods: We elucidated longitudinal
Externí odkaz:
https://doaj.org/article/c92047276de246fc832d975751f88dac
Autor:
Juanjie Tang, Gabrielle Grubbs, Youri Lee, Chang Huang, Supriya Ravichandran, David Forgacs, Hana Golding, Ted M Ross, Surender Khurana
Publikováno v:
EBioMedicine, Vol 74, Iss , Pp 103748- (2021)
Background: Limited knowledge exists regarding antibody affinity maturation following mRNA vaccination in naïve vs. COVID-19 recovered individuals and potential sex differences. Methods: We elucidated post-vaccination antibody profiles of 69 naïve
Externí odkaz:
https://doaj.org/article/eeb972c584c74268a15838a9f93153b5
Autor:
Juanjie Tang, Youri Lee, Supriya Ravichandran, Gabrielle Grubbs, Chang Huang, Charles B. Stauft, Tony Wang, Basil Golding, Hana Golding, Surender Khurana
Publikováno v:
iScience, Vol 24, Iss 9, Pp 103006- (2021)
Summary: Hyperimmune immunoglobulin (hCoV-2IG) generated from SARS-CoV-2 convalescent plasma (CP) are under evaluation in clinical trials. Here we explored the antibody epitope repertoire, and virus neutralizing capacity of six hCoV-2IG batches as we
Externí odkaz:
https://doaj.org/article/38da77a558eb4015a202775993eff935
Autor:
Juanjie Tang, Tanya Novak, Julian Hecker, Gabrielle Grubbs, Fatema Tuz Zahra, Lorenza Bellusci, Sara Pourhashemi, Janet Chou, Kristin Moffitt, Natasha B. Halasa, Stephanie P. Schwartz, Tracie C. Walker, Keiko M. Tarquinio, Matt S. Zinter, Mary A. Staat, Shira J. Gertz, Natalie Z. Cvijanovich, Jennifer E. Schuster, Laura L. Loftis, Bria M. Coates, Elizabeth H. Mack, Katherine Irby, Julie C. Fitzgerald, Courtney M. Rowan, Michele Kong, Heidi R. Flori, Aline B. Maddux, Steven L. Shein, Hillary Crandall, Janet R. Hume, Charlotte V. Hobbs, Adriana H. Tremoulet, Chisato Shimizu, Jane C. Burns, Sabrina R. Chen, Hye Kyung Moon, Christoph Lange, Adrienne G. Randolph, Surender Khurana
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/a92960f10907461dbc77a531a0efcff5
Autor:
Juanjie Tang, Adrienne G. Randolph, Tanya Novak, Tracie C. Walker, Laura L. Loftis, Matt S. Zinter, Katherine Irby, Surender Khurana
Publikováno v:
Vaccines, Vol 10, Iss 2, p 270 (2022)
Mucosal immunity plays an important role in the control of viral respiratory infections like SARS-CoV-2. While systemic immune responses against the SARS-2-CoV-2 have been studied in children, there is no information on mucosal antibody response, esp
Externí odkaz:
https://doaj.org/article/a5c05c4b19064ec8a78f4558e403106d