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of 4
pro vyhledávání: '"Juanita Sanchez Rubiano"'
Discovery of hit compounds for methyl-lysine reader proteins from a target class DNA-encoded library
Autor:
Devan J. Shell, Justin M. Rectenwald, Peter H. Buttery, Rebecca L. Johnson, Caroline A. Foley, Shiva K.R. Guduru, Mélanie Uguen, Juanita Sanchez Rubiano, Xindi Zhang, Fengling Li, Jacqueline L. Norris-Drouin, Matthew Axtman, P. Brian Hardy, Masoud Vedadi, Stephen V. Frye, Lindsey I. James, Kenneth H. Pearce
Publikováno v:
SLAS Discovery, Vol 27, Iss 8, Pp 428-439 (2022)
Methyl-lysine (Kme) reader domains are prevalent in chromatin regulatory proteins which bind post-translational modification sites to recruit repressive and activating factors; therefore, these proteins play crucial roles in cellular signaling and ep
Externí odkaz:
https://doaj.org/article/859446a01131470eb8e3880dae7658e0
Autor:
Appaso M Jadhav, Weichao Li, Louis P. Conway, Christopher G. Parker, Rick A Homan, Richard Hawkins, R. Michael Lawrence, Juanita Sanchez Rubiano
Publikováno v:
Chemical Science
The use of photo-affinity reagents for the mapping of noncovalent small molecule–protein interactions has become widespread. Recently, several ‘fully-functionalized’ (FF) chemical tags have been developed wherein a photoactivatable capture grou
Publikováno v:
Chemical Science; 6/14/2021, Vol. 12 Issue 22, p7589-7599, 11p
Autor:
Conway, Louis P., Jadhav, Appaso M., Homan, Rick A., Li, Weichao, Rubiano, Juanita Sanchez, Hawkins, Richard, Lawrence, R. Michael, Parker, Christopher G.
Publikováno v:
Chemical Science; 6/14/2021, Vol. 12 Issue 22, p7839-7847, 9p