Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Juanita S. Lopez"'
Autor:
Crescens Tiu, Rajiv Shinde, Abhijit Pal, Andrea Biondo, Alex Lee, Nina Tunariu, Shaman Jhanji, Vimal Grover, Kate Tatham, Pascale Gruber, Udai Banerji, Johann S. De Bono, Emma Nicholson, Anna R. Minchom, Juanita S. Lopez
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Pp 189-195 (2021)
Introduction: Immune checkpoint inhibitors (ICIs) are increasingly a standard of care for many cancers; these agents can result in immune-related adverse events (irAEs) including fever, which is common but can rarely be associated with systemic immun
Externí odkaz:
https://doaj.org/article/795643acaadb42b992e7de8af283b261
Autor:
Johann S. de Bono, Yvette Drew, Juanita S. Lopez, Bristi Basu, Ruth Plummer, Udai Banerji, Christopher J. Lord, Andrew Foxley, Justin P.O. Lindemann, Paul Rugman, Emma Hall, Laura Finneran, Karen E. Swales, Shaun Decordova, Florence I. Raynaud, Ruth Ruddle, Nicholas C. Turner, Heidrun Gevensleben, Neha Chopra, Nina Tunariu, Alison Turner, Mona Parmar, Ruth Matthews, Sarah Ward, Daniel Nava Rodrigues, Ines Figueiredo, Susana Miranda, Ruth Riisnaes, Rowan Miller, Desamparados Roda, Suzanne Carreira, Joline S.J. Lim, Stephen J. Pettitt, Vasiliki Michalarea, Rebecca Kristeleit, Timothy A. Yap
Preclinical studies have demonstrated synergy between PARP and PI3K/AKT pathway inhibitors in BRCA1 and BRCA2 (BRCA1/2)–deficient and BRCA1/2-proficient tumors. We conducted an investigator-initiated phase I trial utilizing a prospective intrapatie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01e33adbfd1faf3496d00cefbd4e1d17
https://doi.org/10.1158/2159-8290.c.6547955.v1
https://doi.org/10.1158/2159-8290.c.6547955.v1
Autor:
Johann S. de Bono, Yvette Drew, Juanita S. Lopez, Bristi Basu, Ruth Plummer, Udai Banerji, Christopher J. Lord, Andrew Foxley, Justin P.O. Lindemann, Paul Rugman, Emma Hall, Laura Finneran, Karen E. Swales, Shaun Decordova, Florence I. Raynaud, Ruth Ruddle, Nicholas C. Turner, Heidrun Gevensleben, Neha Chopra, Nina Tunariu, Alison Turner, Mona Parmar, Ruth Matthews, Sarah Ward, Daniel Nava Rodrigues, Ines Figueiredo, Susana Miranda, Ruth Riisnaes, Rowan Miller, Desamparados Roda, Suzanne Carreira, Joline S.J. Lim, Stephen J. Pettitt, Vasiliki Michalarea, Rebecca Kristeleit, Timothy A. Yap
Supplementary Tables 1-7; Supplementary Figures 1-2; Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b42dc1c2ce5b8015019651ef216b42
https://doi.org/10.1158/2159-8290.22535825
https://doi.org/10.1158/2159-8290.22535825
Autor:
Nicholas C. Turner, Juanita S. Lopez, Timothy A. Yap, Emma Hall, Alison Turner, Florence I. Raynaud, Ruth Ruddle, Karen E. Swales, Jason Malia, Laura Finneran, Toby Prout, Mona Parmar, Jenny King, Margaret Hills, Michael Hubank, Paula Z. Proszek, Heidrun Gevensleben, Sarah Hrebien, Alex Pearson, Isaac Garcia-Murillas, Maria Teresa Herrera-Abreu, Rosalind J. Cutts, Alicia F.C. Okines, Alistair Ring, Anne C. Armstrong, Iain R. Macpherson, Joline S.J. Lim, Javier Pascual
Baseline tissue biomarker analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b64d725e62326fa4fbc9ae6bd1b3db
https://doi.org/10.1158/2159-8290.22535447
https://doi.org/10.1158/2159-8290.22535447
Autor:
Nicholas C. Turner, Juanita S. Lopez, Timothy A. Yap, Emma Hall, Alison Turner, Florence I. Raynaud, Ruth Ruddle, Karen E. Swales, Jason Malia, Laura Finneran, Toby Prout, Mona Parmar, Jenny King, Margaret Hills, Michael Hubank, Paula Z. Proszek, Heidrun Gevensleben, Sarah Hrebien, Alex Pearson, Isaac Garcia-Murillas, Maria Teresa Herrera-Abreu, Rosalind J. Cutts, Alicia F.C. Okines, Alistair Ring, Anne C. Armstrong, Iain R. Macpherson, Joline S.J. Lim, Javier Pascual
RMH200 panel design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::463cc86a1d265fa62da6f6887c6a661c
https://doi.org/10.1158/2159-8290.22535438.v1
https://doi.org/10.1158/2159-8290.22535438.v1
Autor:
Nicholas C. Turner, Juanita S. Lopez, Timothy A. Yap, Emma Hall, Alison Turner, Florence I. Raynaud, Ruth Ruddle, Karen E. Swales, Jason Malia, Laura Finneran, Toby Prout, Mona Parmar, Jenny King, Margaret Hills, Michael Hubank, Paula Z. Proszek, Heidrun Gevensleben, Sarah Hrebien, Alex Pearson, Isaac Garcia-Murillas, Maria Teresa Herrera-Abreu, Rosalind J. Cutts, Alicia F.C. Okines, Alistair Ring, Anne C. Armstrong, Iain R. Macpherson, Joline S.J. Lim, Javier Pascual
Cyclin-dependent kinase 4/6 (CDK4/6) and PI3K inhibitors synergize in PIK3CA-mutant ER-positive HER2-negative breast cancer models. We conducted a phase Ib trial investigating the safety and efficacy of doublet CDK4/6 inhibitor palbociclib plus selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2188840c665bdd2ddabfa9e80f44d33
https://doi.org/10.1158/2159-8290.c.6547859.v1
https://doi.org/10.1158/2159-8290.c.6547859.v1
Autor:
Juanita S. Lopez, Nina Tunariu, Johann S. de Bono, Udai Banerji, Anna R. Minchom, Jonathan Ratoff, Joo Ern Ang, Malaka Ameratunga, Miriam Estevez Timon, Dan Bar, Andra Curcean, Mariana Scaranti, Irene Moreno Candilejo, Crescens Tiu, Angelika Terbuch
Figure S2. Continuation of IMP following radiological detection of asymptomatic DILD resulting in clinical deterioration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629d42fa47b66b3f5e57f678ae928b37
https://doi.org/10.1158/1078-0432.22475024.v1
https://doi.org/10.1158/1078-0432.22475024.v1
Autor:
Juanita S. Lopez, Nina Tunariu, Johann S. de Bono, Udai Banerji, Anna R. Minchom, Jonathan Ratoff, Joo Ern Ang, Malaka Ameratunga, Miriam Estevez Timon, Dan Bar, Andra Curcean, Mariana Scaranti, Irene Moreno Candilejo, Crescens Tiu, Angelika Terbuch
Table S1. Frequency of DILD as per category
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7591779790247bf34ccfe47cc3e0371f
https://doi.org/10.1158/1078-0432.22475018
https://doi.org/10.1158/1078-0432.22475018
Autor:
Juanita S. Lopez, Nina Tunariu, Johann S. de Bono, Udai Banerji, Anna R. Minchom, Jonathan Ratoff, Joo Ern Ang, Malaka Ameratunga, Miriam Estevez Timon, Dan Bar, Andra Curcean, Mariana Scaranti, Irene Moreno Candilejo, Crescens Tiu, Angelika Terbuch
Purpose:Drug-induced interstitial lung disease (DILD) is a rare, but potentially fatal toxicity. Clinical and radiological features of DILD in the early experimental setting are poorly described.Patients and Methods:A total of 2,499 consecutive patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de593b8cd345d5233271cdb33caa91d
https://doi.org/10.1158/1078-0432.c.6528971
https://doi.org/10.1158/1078-0432.c.6528971
Autor:
Juanita S. Lopez, Nina Tunariu, Johann S. de Bono, Udai Banerji, Anna R. Minchom, Jonathan Ratoff, Joo Ern Ang, Malaka Ameratunga, Miriam Estevez Timon, Dan Bar, Andra Curcean, Mariana Scaranti, Irene Moreno Candilejo, Crescens Tiu, Angelika Terbuch
Figure S1A. Correlation of patterns of DILD as per ATS/ERS classification and clinical severity. AIP correlated significantly with worse severity (P=0.002). NSIP, non-specific interstitial pneumonia; COP, cryptogenic organizing pneumonia; AIP, acute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b224b05afd94408f64a03c6a1086a4d3
https://doi.org/10.1158/1078-0432.22475021.v1
https://doi.org/10.1158/1078-0432.22475021.v1