Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Juanelle Little Lambert"'
Autor:
Norma Lindsey Buchanan, Michael G. Ramsey, Kevin J. Edgar, Thomas Zoeller, Charles Michael Buchanan, Sandra Klein, Juanelle Little Lambert, Michael F. Wempe
Publikováno v:
Journal of Pharmacy and Pharmacology. 61:23-30
Objectives Glyburide, an important drug for type 2 diabetes, has extremely poor aqueous solubility and resulting low bioavailability. This study describes the ability of hydroxybutenyl-β-cyclodextrin (HBenBCD) to form complexes with glyburide, with
Autor:
Norma Lindsey Buchanan, Kevin J. Edgar, Charles Michael Buchanan, Jessica Dee Posey-Dowty, Juanelle Little Lambert, Michael G. Ramsey, Michael F. Wempe
Publikováno v:
Journal of Pharmaceutical Sciences. 95:2246-2255
The solubility and dissolution of tamoxifen base and tamoxifen citrate with and without hydroxybutenyl‐β‐cyclodextrin (HBenBCD) in aqueous and organic media were examined. The solubility of tamoxifen was greatly enhanced by complexation with HBe
Autor:
Susan R. Alderson, Daniel Wayne Dixon, Jozsef Szejtli, Rick J. Offerman, Róbert Iványi, Lajos Szente, Douglas W. Lowman, Juanelle Little Lambert, Curtis D. Cleven, Charles Michael Buchanan
Publikováno v:
Carbohydrate Research. 337:493-507
We have examined the synthesis of hydroxybutenyl cyclomaltooligosaccharides (cyclodextrins) and the ability of these cyclodextrin ethers to form guest–host complexes with guest molecules. The hydroxybutenyl cyclodextrin ethers were prepared by a ba