Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Juana M Flores"'
A mouse model for Li-Fraumeni-Like Syndrome with cardiac angiosarcomas associated to POT1 mutations.
Autor:
Paula Martínez, Raúl Sánchez-Vázquez, Iole Ferrara-Romeo, Rosa Serrano, Juana M Flores, Maria A Blasco
Publikováno v:
PLoS Genetics, Vol 18, Iss 6, p e1010260 (2022)
The shelterin protein POT1 has been found mutated in many different familial and sporadic cancers, however, no mouse models to understand the pathobiology of these mutations have been developed so far. To address the molecular mechanisms underlying t
Externí odkaz:
https://doaj.org/article/a5c795121fee4cf6b6589dd22b10f7bf
Autor:
María García‐Beccaria, Paula Martínez, Marinela Méndez‐Pertuz, Sonia Martínez, Carmen Blanco‐Aparicio, Marta Cañamero, Francisca Mulero, Chiara Ambrogio, Juana M Flores, Diego Megias, Mariano Barbacid, Joaquín Pastor, Maria A Blasco
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 7, Pp 930-949 (2015)
Abstract Telomeres are considered anti‐cancer targets, as telomere maintenance above a minimum length is necessary for cancer growth. Telomerase abrogation in cancer‐prone mouse models, however, only decreased tumor growth after several mouse gen
Externí odkaz:
https://doaj.org/article/9d184454ee944308a85f34b3438cb76b
Autor:
Natalia Sacilotto, Josefa Castillo, Ángela L Riffo-Campos, Juana M Flores, Olivia Hibbitt, Richard Wade-Martins, Carlos López, M Isabel Rodrigo, Luis Franco, Gerardo López-Rodas
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132477 (2015)
The prognosis of hepatocellular carcinoma patients is usually poor, the size of tumors being a limiting factor for surgical treatments. Present results suggest that the overexpression of Gas1 (growth arrest specific 1) gene reduces the size, prolifer
Externí odkaz:
https://doaj.org/article/6fe8b18a1a6843d19fd8f8d2fb284d42
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53760 (2013)
Caloric restriction (CR), a reduction of food intake while avoiding malnutrition, can delay the onset of cancer and age-related diseases in several species, including mice. In addition, depending of the genetic background, CR can also increase or dec
Externí odkaz:
https://doaj.org/article/8f7fba8dd6f641bfa6c085b5d64d3f8d
Autor:
María Fernández-Velasco, Patricia Prieto, Verónica Terrón, Gemma Benito, Juana M Flores, Carmen Delgado, Carlos Zaragoza, Begoña Lavin, Mónica Gómez-Parrizas, Eduardo López-Collazo, Paloma Martín-Sanz, Lisardo Boscá
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45260 (2012)
The innate immune system is responsible for the initial response of an organism to potentially harmful stressors, pathogens or tissue injury, and accordingly plays an essential role in the pathogenesis of many inflammatory processes, including some c
Externí odkaz:
https://doaj.org/article/9821bf1d09624a5295cf514a18229d71
Autor:
Pablo J Fernandez-Marcos, Cristina Pantoja, Agueda Gonzalez-Rodriguez, Nicholas Martin, Juana M Flores, Angela M Valverde, Eiji Hara, Manuel Serrano
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8744 (2010)
Sei1 is a positive regulator of proliferation that promotes the assembly of Cdk4-cyclin D complexes and enhances the transcriptional activity of E2f1. The potential oncogenic role of Sei1 is further suggested by its overexpression in various types of
Externí odkaz:
https://doaj.org/article/a28fc3ada2224ca4b50dda1362eee713
Autor:
Amparo Cano, Francisco Portillo, Angels Fabra, Juana M. Flores, Gema Moreno-Bueno, David Olmeda
Supplementary Figure 4 from SNAI1 Is Required for Tumor Growth and Lymph Node Metastasis of Human Breast Carcinoma MDA-MB-231 Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d7a65fa01dcd51a7986e877c51fdee
https://doi.org/10.1158/0008-5472.22370879.v1
https://doi.org/10.1158/0008-5472.22370879.v1
Autor:
Amparo Cano, Francisco Portillo, Angels Fabra, Juana M. Flores, Gema Moreno-Bueno, David Olmeda
Supplementary Legends 1-5 from SNAI1 Is Required for Tumor Growth and Lymph Node Metastasis of Human Breast Carcinoma MDA-MB-231 Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b562017b9f256976430010a778b8ec85
https://doi.org/10.1158/0008-5472.22370873
https://doi.org/10.1158/0008-5472.22370873
Autor:
Amparo Cano, Francisco Portillo, Angels Fabra, Juana M. Flores, Gema Moreno-Bueno, David Olmeda
Supplementary Figure 1 from SNAI1 Is Required for Tumor Growth and Lymph Node Metastasis of Human Breast Carcinoma MDA-MB-231 Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0225250e15f98c54a67a41d4546384a2
https://doi.org/10.1158/0008-5472.22370888
https://doi.org/10.1158/0008-5472.22370888
Autor:
Amparo Cano, Francisco Portillo, Angels Fabra, Juana M. Flores, Gema Moreno-Bueno, David Olmeda
Supplementary Figure 2 from SNAI1 Is Required for Tumor Growth and Lymph Node Metastasis of Human Breast Carcinoma MDA-MB-231 Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141a21ce60910cf8b820245794e7b7b2
https://doi.org/10.1158/0008-5472.22370885
https://doi.org/10.1158/0008-5472.22370885