Zobrazeno 1 - 10
of 148
pro vyhledávání: '"JuanJuan Xiang"'
Autor:
Lujuan Wang, Na Yin, Wenhua Shi, Yaohuan Xie, Junqi Yi, Ziying Tang, Jingqun Tang, Juanjuan Xiang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 648-658 (2024)
Lung cancer’s mortality is predominantly linked to post-chemotherapy recurrence, driven by the reactivation of dormant cancer cells. Despite the critical role of these reactivated cells in cancer recurrence and metastasis, the molecular mechanisms
Externí odkaz:
https://doaj.org/article/e8279a0c7a1b4c57a967f38da39ad1f5
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Eph receptors constitute the largest family of receptor tyrosine kinases, comprising 14 distinct members classified into two subgroups: EphAs and EphBs.. Despite their essential functions in normal physiological processes, accumulating evide
Externí odkaz:
https://doaj.org/article/bb917e2f75794fefa2787d75710e2609
Autor:
Yiming Zhao, Junqi Yi, Juanjuan Xiang, Wei Jia, Anqi Chen, Liyu Chen, Leliang Zheng, Wen Zhou, Minghua Wu, Zheng Yu, Jingqun Tang
Publikováno v:
BMC Microbiology, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract As the Human Microbiome Project (HMP) progresses, the relationship between microbes and human health has been receiving increasing attention. A growing number of reports support the correlation between cancer and microbes. However, most stud
Externí odkaz:
https://doaj.org/article/cecbabeb8d444ed8828038d30143f62d
Autor:
Lujuan Wang, Qiu Peng, Yaohuan Xie, Na Yin, Jiaqi Xu, Anqi Chen, Junqi Yi, Wenhua Shi, Jingqun Tang, Juanjuan Xiang
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-17 (2022)
Abstract Reactivation of chemotherapy-induced dormant cancer cells is the main cause of relapse and metastasis. The molecular mechanisms underlying remain to be elucidated. In this study, we introduced a cellular model that mimics the process of cisp
Externí odkaz:
https://doaj.org/article/864b736ecba341748dee9a189e76313e
Autor:
Shuai Wang, Huiting Li, Jiheng Liu, Qianqian Zhang, Wei Xu, Juanjuan Xiang, Li Fang, Ping Xu, Zheng Li
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract RNA methylation modifications, especially m6A mRNA modification, are known to be extensively involved in tumor development. However, the relationship between N3-methylcytidine (m3C) related genes and tumorigenesis has rarely been studied. In
Externí odkaz:
https://doaj.org/article/079dc752d42c4fc0aa3f761bb4fa5215
Autor:
Wei Xu, Linna Chen, Jiheng Liu, Zhezhe Zhang, Ranran Wang, Qianqian Zhang, Huiting Li, Juanjuan Xiang, Li Fang, Ping Xu, Zheng Li
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-13 (2022)
Abstract Lung adenocarcinoma (LUAD) is one of the main causes of cancer-related mortality, with a strong tendency to metastasize early. Transforming growth factor-β (TGF-β) signaling is a powerful regulator to promote metastasis of LUAD. Here, we s
Externí odkaz:
https://doaj.org/article/cf1745459c754114bf960344c8e86ba3
Blocking glycine utilization inhibits multiple myeloma progression by disrupting glutathione balance
Autor:
Jiliang Xia, Jingyu Zhang, Xuan Wu, Wanqing Du, Yinghong Zhu, Xing Liu, Zhenhao Liu, Bin Meng, Jiaojiao Guo, Qin Yang, Yihui Wang, Qinglin Wang, Xiangling Feng, Guoxiang Xie, Yi Shen, Yanjuan He, Juanjuan Xiang, Minghua Wu, Gang An, Lugui Qiu, Wei Jia, Wen Zhou
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The bone tumour microenvironment plays an essential role in multiple myeloma (MM) development. Here, the authors show that bone collagen degradation provides glycine to support MM progression through glutathione and purine synthesis.
Externí odkaz:
https://doaj.org/article/ef6ec5c2a5274ceba7416ff777f570e6
Autor:
Lujuan Wang, Qiu Peng, Na Yin, Yaohuan Xie, Jiaqi Xu, Anqi Chen, Junqi Yi, Jingqun Tang, Juanjuan Xiang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 269-279 (2021)
Cisplatin-based chemotherapy remains the standard care for non-small cell lung cancer (NSCLC) patients. Relapse after chemotherapy-induced dormancy affects the overall survival of patients. The evolution of cancer cells under chemotherapy stress is r
Externí odkaz:
https://doaj.org/article/b634269eb1c54ab892ebafcdf4aac7cb
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionLung cancer is the leading cause of cancer-related deaths worldwide. Chemotherapy kills most cancer cells; however, residual cells enter a dormant state. The dormant cancer cells can be reactivated under specific circumstances. The “pre
Externí odkaz:
https://doaj.org/article/4a200419277e4cb5980798b71bc0492e
Publikováno v:
Thoracic Cancer, Vol 12, Iss 19, Pp 2601-2610 (2021)
Abstract Background Cisplatin‐based chemotherapy is a therapeutic strategy against non‐small cell lung cancer (NSCLC). However, cancers relapse after chemotherapy due to a dormant state of residual cancer cells. Extracellular vesicles and particl
Externí odkaz:
https://doaj.org/article/b3fae45312674cfabe0515b8ff9f0efd