Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Juan-Lucio Iovanna"'
Autor:
Thomas Bonacci, Stéphane Audebert, Luc Camoin, Emilie Baudelet, Juan-Lucio Iovanna, Philippe Soubeyran
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169988 (2017)
NUB1 (Nedd8 ultimate buster 1) is an adaptor protein which negatively regulates the ubiquitin-like protein Nedd8 as well as neddylated proteins levels through proteasomal degradation. However, molecular mechanisms underlying this function are not com
Externí odkaz:
https://doaj.org/article/8e43a0b5d473413f8fe65e9992423089
Autor:
Daniele Fanale, Chiara Brando, Lidia Rita Corsini, Sofia Cutaia, Mariano Catello Di Donna, Ugo Randazzo, Clarissa Filorizzo, Chiara Lisanti, Luigi Magrin, Vittorio Gurrera, Raffaella Romano, Alessandra Dimino, Tancredi Didier Bazan Russo, Daniel Olive, Salvatore Vieni, Gianni Pantuso, Antonio Giordano, Vito Chiantera, Antonio Russo, Viviana Bazan, Juan Lucio Iovanna
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background The most common subtype of ovarian cancer (OC) showing immunogenic potential is represented by the high-grade serous ovarian cancer (HGSOC), which is characterized by the presence of tumor-infiltrating immune cells able to modulat
Externí odkaz:
https://doaj.org/article/dfb910f19c8541319a410ae55d310035
Autor:
Daniele Fanale, Lidia Rita Corsini, Chiara Brando, Sofia Cutaia, Mariano Catello Di Donna, Clarissa Filorizzo, Maria Chiara Lisanti, Ugo Randazzo, Luigi Magrin, Raffaella Romano, Tancredi Didier Bazan Russo, Daniel Olive, Salvatore Vieni, Gianni Pantuso, Vito Chiantera, Antonio Russo, Viviana Bazan, Juan Lucio Iovanna
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The most common subtype of ovarian cancer (OC) is the high-grade serous ovarian carcinoma (HGSOC), accounting for 70%–80% of all OC deaths. Although HGSOC is a potentially immunogenic tumor, clinical studies assessing the effectiveness of inhibitor
Externí odkaz:
https://doaj.org/article/c26e4c93055a4acdb59f8734e5f341e3
Autor:
Aurelio Seidita, Maurizio Soresi, Lydia Giannitrapani, Vita Di Stefano, Roberto Citarrella, Luigi Mirarchi, Antonella Cusimano, Giuseppa Augello, Antonio Carroccio, Juan Lucio Iovanna, Melchiorre Cervello
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
For years it has been established that the only truly effective treatment of metabolic syndrome (MS) is lifestyle modification to prevent its cardiovascular (e.g., coronary artery disease and atherosclerosis), metabolic (e.g., diabetes mellitus), and
Externí odkaz:
https://doaj.org/article/d3b00827487a41ba834ac84126f79f0d
Autor:
Marjorie Adjuto-Saccone, Philippe Soubeyran, Julie Garcia, Stéphane Audebert, Luc Camoin, Marion Rubis, Julie Roques, Bernard Binétruy, Juan Lucio Iovanna, Roselyne Tournaire
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-15 (2021)
Abstract Endothelial–mesenchymal transition (EndMT) is an important source of cancer-associated fibroblasts (CAFs), which facilitates tumour progression. PDAC is characterised by abundant CAFs and tumour necrosis factor-α (TNF-α). Here, we show t
Externí odkaz:
https://doaj.org/article/3aa8e654cca2441fad193adeb9b1e12e
Autor:
Daniele Fanale, Lidia Rita Corsini, Chiara Brando, Alessandra Dimino, Clarissa Filorizzo, Luigi Magrin, Roberta Sciacchitano, Alessia Fiorino, Tancredi Didier Bazan Russo, Valentina Calò, Juan Lucio Iovanna, Edoardo Francini, Antonio Russo, Viviana Bazan
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Lynch syndrome (LS) is an inherited genetic condition associated with increased predisposition to colorectal cancer (CRC) and other tumors and is caused by germline mutations in Mismatch Repair (MMR) or EPCAM genes. The identification of LS carriers
Externí odkaz:
https://doaj.org/article/e1f693512574436f83b0c150e76c619e
Autor:
Lorena Incorvaia, Daniele Fanale, Giuseppe Badalamenti, Camillo Porta, Daniel Olive, Ida De Luca, Chiara Brando, Mimma Rizzo, Carlo Messina, Mattia Rediti, Antonio Russo, Viviana Bazan, Juan Lucio Iovanna
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Despite a proportion of renal cancer patients can experiment marked and durable responses to immune-checkpoint inhibitors, the treatment efficacy is widely variable and identifying the patient who will benefit from immunotherapy remains an issue. We
Externí odkaz:
https://doaj.org/article/dfcd947f0514466dbd4babe39bc9b655
Autor:
Orianne Olivares, Jared R. Mayers, Victoire Gouirand, Margaret E. Torrence, Tristan Gicquel, Laurence Borge, Sophie Lac, Julie Roques, Marie-Noëlle Lavaut, Patrice Berthezène, Marion Rubis, Veronique Secq, Stéphane Garcia, Vincent Moutardier, Dominique Lombardo, Juan Lucio Iovanna, Richard Tomasini, Fabienne Guillaumond, Matthew G. Vander Heiden, Sophie Vasseur
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Cancer cells adapt their metabolism to survive limited nutrient availability. Here, the authors show that in conditions of limited glucose or glutamine availability, pancreatic ductal adenocarcinoma cells can use collagen-derived proline to foster th
Externí odkaz:
https://doaj.org/article/6a73d2e74efe45e79489251d11428d7b
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Extracellular vesicles (EVs), including exosomes and microvesicles, are nano-sized membrane vesicles containing proteins and nucleic acids, which act as intercellular messengers. They play an important role in a variety of physiological proc
Externí odkaz:
https://doaj.org/article/18aa00ec6b494d09b82b1dba44412178
Autor:
Philippe Soubeyran, Juan-Lucio Iovanna, Anne Pierres, Bénédicte Masson, Stéphane Garcia, Frédéric André, Julie Roignot, David Taieb
Supplementary Table 1, Figures 1-8 from ArgBP2-Dependent Signaling Regulates Pancreatic Cell Migration, Adhesion, and Tumorigenicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9f3157ee53fb6f69a24662402389b9
https://doi.org/10.1158/0008-5472.22377045
https://doi.org/10.1158/0008-5472.22377045
