Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Juan-Li Gu"'
Autor:
Weike Bao, Juan-Li Gu, Eliot H. Ohlstein, Tian-Li Yue, Douglas T. Thudium, Anne M. Romanic, Cynthia L. Burns-Kurtis, Beat M. Jucker, Jianqi Cui, Rogely W. Boyce, Karpagam Aravindhan, Peter Brown, Rosanna C. Mirabile
Publikováno v:
Circulation. 108:2393-2399
Background— Peroxisome proliferator–activated receptor-α (PPAR-α) is expressed in the heart and regulates genes involved in myocardial fatty acid oxidation (FAO). The role of PPAR-α in acute ischemia/reperfusion myocardial injury remains uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf0c8e56a816530a86fa753831bdba7
https://doi.org/10.1161/01.cir.0000093187.42015.6c
https://doi.org/10.1161/01.cir.0000093187.42015.6c
Autor:
Eliot H. Ohlstein, Tian-Li Yue, Andrew A. Parsons, Juan-Li Gu, Alastair D. Reith, Beverly E. Maleeff, Yibin Wang, Reinhold Kreutz, John C. Lee, Rosanna C. Mirabile, Chuanlin Wang
Publikováno v:
Journal of Biological Chemistry. 275:37895-37901
The extracellular signal-regulated kinase (ERK) pathway is activated by hypertrophic stimuli in cardiomyocytes. However, whether ERK plays an essential role or is implicated in all major components of cardiac hypertrophy remains controversial. Using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43dab2d3eb0122a42db8582a5620dff8
https://doi.org/10.1074/jbc.m007037200
https://doi.org/10.1074/jbc.m007037200
Autor:
Juan-Li Gu, Giora Z. Feuerstein, Timothy K. Hart, Paul W. Keller, Guo-Liang Yu, Sanjay Kumar, Jian Ni, Zhengui Xia, Xinkang Wang, Walter E. DeWolf, Tian-Li Yue, Chuanlin Wang, Anne M. Romanic
Publikováno v:
Journal of Biological Chemistry. 274:1479-1486
TL1 is a recently discovered novel member of the tumor necrosis factor (TNF) cytokine family. TL1 is abundantly expressed in endothelial cells, but its function is not known. The present study was undertaken to explore whether TL1 induces apoptosis i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dfaee2fb8b8d45273ada08cba58390d
https://doi.org/10.1074/jbc.274.3.1479
https://doi.org/10.1074/jbc.274.3.1479
Publikováno v:
European Journal of Pharmacology. 345:61-65
Stress-activated protein kinase (SAPK/JNK) has been implicated in the signaling pathway that leads to cell death. Carvedilol, a new vasodilating beta-adrenoceptor antagonist with potent antioxidant activity, has been shown to convey a high degree of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300379ee8ab0c95d57e6b91e133fb8ea
https://doi.org/10.1016/s0014-2999(98)00053-3
https://doi.org/10.1016/s0014-2999(98)00053-3
Autor:
Robert R. Ruffolo, Giora Z. Feuerstein, Xinkang Wang, Anne M. Romanic, Calvert Louden, Gao Lin Liu, Juan Li Gu, George Poste, Tian Li Yue, Xin-Liang Ma, Sanjay Kumar
Publikováno v:
Circulation Research. 82:166-174
Abstract —Carvedilol, a new vasodilating β-adrenoceptor antagonist and a potent antioxidant, produces a high degree of cardioprotection in a variety of experimental models of ischemic cardiac injury. Recent clinical studies in patients with heart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31aac5f8e09d93b4bd5906081ac9b9fb
https://doi.org/10.1161/01.res.82.2.166
https://doi.org/10.1161/01.res.82.2.166
Autor:
Xinkang Wang, Kodandaram Pillarisetti, Giora Z. Feuerstein, Tian-Li Yue, Juan-Li Gu, Shalley K. Gupta, Timothy K. Hart, Calvert Louden, Paul G. Lysko
Publikováno v:
Molecular Pharmacology. 51:951-962
2-Methoxyestradiol (2-ME) is an endogenous metabolite of estradiol-17beta and the oral contraceptive agent 17-ethylestradiol. 2-ME was recently reported to inhibit endothelial cell proliferation. The current study was undertaken to explore the mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3c1666d66f9bdcb50e4a5261bd960a
https://doi.org/10.1124/mol.51.6.951
https://doi.org/10.1124/mol.51.6.951
Publikováno v:
Stroke. 25:2476-2482
Studies examining the role of tetrodotoxin-sensitive ion channels in hypoxic-ischemic neuronal damage have concluded that sodium influx is an important initiating event. We examined the neuroprotectant effect of tetrodotoxin on both cultured cerebell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e144697decef8a1653471365fa2ac54d
https://doi.org/10.1161/01.str.25.12.2476
https://doi.org/10.1161/01.str.25.12.2476
Autor:
Tian-Li Yue, Kathryn A. Lysko, Giora Feuerstein, Paul G. Lysko, Patrick J. McKenna, Robert R. Ruffolo, Juan-Li Gu
Publikováno v:
European Journal of Pharmacology. 251:237-243
The antioxidant effects of SB 211475, a metabolite of carvedilol, a novel antihypertensive agent, were studied and compared with carvedilol and other antioxidants such as U78517F, U74500A and probucol. SB 211475 inhibited Fe(2+)-vitamin C-initiated l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1edf18ba2d67717a9b52d3dcc2f66101
https://doi.org/10.1016/0014-2999(94)90405-7
https://doi.org/10.1016/0014-2999(94)90405-7
Publikováno v:
European Journal of Pharmacology. 240:81-84
The chemotactic activity of interleukin-8 for human aortic smooth muscle cells was investigated in Transwell cell culture chamber using a polycarbonate membrane with pores of 8 microns. Interleukin-8 stimulated the smooth muscle cell migration time a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1445c311ea08a999ac7636b27f2d7f61
https://doi.org/10.1016/0014-2999(93)90549-w
https://doi.org/10.1016/0014-2999(93)90549-w
Publikováno v:
Brain Research. 610:53-56
alpha-Tocopherol (alpha-TC) is considered an important endogenous brain antioxidant. The utility of brain alpha-TC levels as an index of in vivo lipid peroxidation has recently been suggested. Therefore, we explored the significance of alpha-TC level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963ef0f5d2e64810505a46a8bdf66f50
https://doi.org/10.1016/0006-8993(93)91215-e
https://doi.org/10.1016/0006-8993(93)91215-e