Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Juan-Juan Zhu"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2606-2614 (2024)
Cathepsin L (CTSL) is a promising therapeutic target for metabolic disorders. Current pharmacological interventions targeting CTSL have demonstrated potential in reducing body weight gain, serum insulin levels, and improving glucose tolerance. Howeve
Externí odkaz:
https://doaj.org/article/da7039a22cfa4c6bbf060a08010e244f
Autor:
Jing Lu, Ru-Xuan Zhao, Feng-Ran Xiong, Juan-Juan Zhu, Ting-Ting Shi, Ying-Chao Zhang, Gong-Xin Peng, Jin-Kui Yang
Publikováno v:
Molecular Metabolism, Vol 80, Iss , Pp 101885- (2024)
Objective: Genome-scale CRISPR–Cas9 knockout coupled with single-cell RNA sequencing (scRNA-seq) has been used to identify function-related genes. However, this method may knock out too many genes, leading to low efficiency in finding genes of inte
Externí odkaz:
https://doaj.org/article/614360d6b4b7461a94a1a202764b2001
Autor:
Jing Lu, Ting-Ting Shi, Sha-Sha Yuan, Rong-Rong Xie, Ru-Xuan Zhao, Juan-Juan Zhu, Jin-Kui Yang
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Mutations in KCNH6 has been proved to cause hypoinsulinemia and diabetes in human and mice. Cisapride is a stomach–intestinal motility drug used to treat gastrointestinal dysfunction. Cisapride has been reported to be a potential inhibitor of the K
Externí odkaz:
https://doaj.org/article/300f94c389f24b9d932ea44c1bb03a06
Autor:
Juan-Juan Zhu, Zhi-Tong Jiang, Chen Liu, Yi-Feng Xi, Jin Wang, Fang-Fang Yang, Wei-Juan Yao, Wei Pang, Li-Li Han, Yong-He Zhang, An-Qiang Sun, Jing Zhou
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Disturbed blood flow has been recognized to promote platelet aggregation and thrombosis via increasing accumulation of von Willebrand factor (VWF) at the arterial post-stenotic sites. The mechanism underlying the disturbed-flow regulated endothelial
Externí odkaz:
https://doaj.org/article/ef005f5dc66d446aafc427f7abe8dcc2
Autor:
Xue-Ke Zhao, Lei Yu, Ming-Liang Cheng, Pulin Che, Yin-Ying Lu, Quan Zhang, Mao Mu, Hong Li, Li-Li Zhu, Juan-Juan Zhu, Meng Hu, Po Li, Yue-Dong Liang, Xin-Hua Luo, Yi-Ju Cheng, Zhi-Xiang Xu, Qiang Ding
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Understanding the underlying molecular mechanisms of liver fibrosis is important to develop effective therapy. Herein, we show that focal-adhesion-kinse (FAK) plays a key role in promoting hepatic stellate cells (HSCs) activation in vitro an
Externí odkaz:
https://doaj.org/article/0be84a8d4f6043a6b8939f2069666e82
Autor:
Ming-Bao Luan, Ze-Mao Yang, Juan-Juan Zhu, Xin Deng, Chen-Chen Liu, Xiao-Fei Wang, Ying Xu, Zhi-Min Sun, Jian-Hua Chen
Publikováno v:
Acta Societatis Botanicorum Poloniae, Vol 85, Iss 3 (2016)
To provide a theoretical and practical foundation for ramie genetic analysis, simple sequence repeats (SSRs) were identified in the ramie genome and employed in this study. From the 115 369 sequences of a specific-locus amplified fragment library, a
Externí odkaz:
https://doaj.org/article/441daca075ad4f82bdff6b845e2023cd
Publikováno v:
Journal of Integrative Agriculture, Vol 11, Iss 6, Pp 927-937 (2012)
Relative leaf chlorophyll (Chl.) content, leaf gas exchange, Chl. fluorescence, plant biological biomass, and fruit yield were evaluated in growing hot pepper (Capsicum annuum L.) during the fruit-growing stages in hot summer under three shade levels
Externí odkaz:
https://doaj.org/article/ddcc244abe8b45efb66eec6ebc562392
Publikováno v:
Molecules, Vol 23, Iss 1, p 101 (2018)
Ethanol extract (EE) from Periplaneta americana (PA) is the main ingredient of Kangfuxin, which is a popular traditional chinese medicine (TCM) and has long been used for the clinical treatment of burns, wounds and ulcers. We compared the wound-heali
Externí odkaz:
https://doaj.org/article/c1f488a0806840969c47ebba943316e0
Autor:
Min Lin, Ying-Fang Wen, Jiao-Ren Wu, Qian Wang, Lei Zheng, Gui-Rong Liu, Yue Huang, Hui Yang, Fen Lin, Xiao-Fen Zhan, Chun-Ping Lin, Hui-Tian Yang, Qiu-Qing Weng, Fen-Ting Huang, Yuan Wang, Mei-Qiong Yao, Hui-Zhou Chen, Di-Hong Wu, Jing-Bo Zeng, Ri-Xin Zeng, Hua Yang, Gui-Cai Li, Min Lu, Juan-Juan Zhu, Long-Xu Xie, Jun-Li Wang, Li-Ye Yang
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55024 (2013)
BACKGROUND: Hemoglobinopathies are the most common inherited diseases in southern China. However, there have been only a few epidemiological studies of hemoglobinopathies in Guangdong province. MATERIALS AND METHODS: Peripheral blood samples were col
Externí odkaz:
https://doaj.org/article/596ec508e300495bb7424009bd31acb0
Autor:
Gang Wei1,2,3,4 gangwei@mail.ccmu.edu.cn, Juan-Juan Zhu1, Feng-Jie Shen1, Rong-Rong Xie1, Chen-Yang Zhang1, Yuan Wang1, Ting-Ting Shi1, Xi Cao1, Xin Ding5 dingxin66@mail.ccmu.edu.cn, Jin-Kui Yang1 jkyang@ccmu.edu.cn
Publikováno v:
Journal of Molecular Endocrinology. Aug2024, Vol. 73 Issue 2, p1-18. 18p.