Zobrazeno 1 - 10
of 287
pro vyhledávání: '"Juan-José Lozano"'
Autor:
Joan Clària, Ferran Aguilar, Juan-José Lozano, Laura Jiménez-Gracia, Juan C. Nieto, Berta Romero-Grimaldo, Xavi Marcos-Fa, Emma Giarracco, Emmanuel Weiss, Jonel Trebicka, Inmaculada Hernàndez, Javier Fernandez, Mireia Casulleras, Cristina López-Vicario, Sinan Muldur, Alex Hopke, Alexandru Vlagea, Ana M. Aransay, Domenica Marchese, Mauro Bernardi, Rajiv Jalan, Paolo Angeli, Giuliana Magri, Andrea Cerutti, Daniel Irimia, Holger Heyn, Vicente Arroyo, Richard Moreau
Publikováno v:
JHEP Reports, Vol 6, Iss 11, Pp 101184- (2024)
Background & Aims: Patients with acutely decompensated (AD) cirrhosis are immunocompromised and particularly susceptible to infections. This study investigated the immunomodulatory actions of albumin by which this protein may lower the incidence of i
Externí odkaz:
https://doaj.org/article/02a18a65ecb849b786c19610418eddc6
Autor:
Javier Gómez-Matas, Saray Duran-Sanchon, Juan-José Lozano, Giulio Ferrero, Sonia Tarallo, Barbara Pardini, Alessio Naccarati, Antoni Castells, Meritxell Gironella
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109283- (2024)
Summary: Small nucleolar RNAs (snoRNAs) have been identified dysregulated in several pathologies, and these alterations can be detected in tissues and in circulation. The main aim of this study was to analyze the whole snoRNome in advanced colorectal
Externí odkaz:
https://doaj.org/article/727c72f433dd4b3cb0988889db92c8bc
Autor:
Trishan Vaikunthanathan, Emmanuelle Landmann, Diana Marin Correa, Marco Romano, Silvia Cellone Trevelin, Qi Peng, Elena Crespo, Mauro Corrado, Juan-José Lozano, Erika L. Pearce, Elena Perpinan, Anna Zoccarato, Leonard Siew, Joy Edwards-Hicks, Reenam Khan, Nguyet-Thin Luu, Mark R. Thursz, Philip N. Newsome, Marc Martinez-Llordella, Naina Shah, Robert I. Lechler, Ajay M. Shah, Alberto Sanchez-Fueyo, Giovanna Lombardi, Niloufar Safinia
Publikováno v:
EBioMedicine, Vol 95, Iss , Pp 104778- (2023)
Summary: Background: Dysregulated inflammatory responses and oxidative stress are key pathogenic drivers of chronic inflammatory diseases such as liver cirrhosis (LC). Regulatory T cells (Tregs) are essential to prevent excessive immune activation an
Externí odkaz:
https://doaj.org/article/2057022316c44f44b2bce7e9345fbc6f
Autor:
Lidia Sanchez-Moral, Tony Paul, Clara Martori, Joan Font-Díaz, Lucía Sanjurjo, Gemma Aran, Érica Téllez, Julià Blanco, Jorge Carrillo, Masaoki Ito, Martina Tuttolomondo, Henrik J. Ditzel, Caterina Fumagalli, Gustavo Tapia, Julia Sidorova, Helena Masnou, Marco-Antonio Fernández-Sanmartín, Juan-José Lozano, Cristina Vilaplana, Alhelí Rodriguez-Cortés, Carolina Armengol, Annabel F. Valledor, Leonor Kremer, Maria-Rosa Sarrias
Publikováno v:
EBioMedicine, Vol 91, Iss , Pp 104555- (2023)
Summary: Background: Reprogramming of immunosuppressive tumor-associated macrophages (TAMs) presents an attractive therapeutic strategy in cancer. The aim of this study was to explore the role of macrophage CD5L protein in TAM activity and assess its
Externí odkaz:
https://doaj.org/article/36b0af9808e741e2b4807b241a0bfa38
Autor:
Angèle Tingaud-Sequeira, Juan-José Lozano, Cinta Zapater, David Otero, Michael Kube, Richard Reinhardt, Joan Cerdà
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64410 (2013)
Delayed hatching is a form of dormancy evolved in some amphibian and fish embryos to cope with environmental conditions transiently hostile to the survival of hatchlings or larvae. While diapause and cryptobiosis have been extensively studied in seve
Externí odkaz:
https://doaj.org/article/6faac228af6c4315a923b91cc696d729
Autor:
Isabel Graupera, Laura Isus, Mar Coll, Elisa Pose, Alba Díaz, Julia Vallverdú, Teresa Rubio-Tomás, Celia Martínez-Sánchez, Patricia Huelin, Marta Llopis, Cristina Solé, Elsa Solà, Constantino Fondevila, Juan José Lozano, Pau Sancho-Bru, Pere Ginès, Patrick Aloy
Publikováno v:
JHEP Reports, Vol 4, Iss 6, Pp 100482- (2022)
Background & Aims: The molecular mechanisms driving the progression from early-chronic liver disease (CLD) to cirrhosis and, finally, acute-on-chronic liver failure (ACLF) are largely unknown. Our aim was to develop a protein network-based approach t
Externí odkaz:
https://doaj.org/article/4d279b50e65d4f14a2a246d30b4f3ba4
Autor:
Tiong Y. Lim, Elena Perpiñán, Maria-Carlota Londoño, Rosa Miquel, Paula Ruiz, Ada S. Kurt, Elisavet Kodela, Amy R. Cross, Claudia Berlin, Joanna Hester, Fadi Issa, Abdel Douiri, Felix H. Volmer, Richard Taubert, Evangelia Williams, Anthony J. Demetris, Andrew Lesniak, Gilbert Bensimon, Juan José Lozano, Marc Martinez-Llordella, Tim Tree, Alberto Sánchez-Fueyo
Publikováno v:
Journal of Hepatology. 78:153-164
Background & Aims:CD4+CD25+Foxp3+regulatory T cells (Tregs) are essential to maintain immunological tolerance and have been shown to promote liver allograft tolerance in both rodents and humans. Low-dose IL-2 (LDIL-2) can expand human endogenous circ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b02e2a66c15aab926a0ac9ea4c4707
https://doi.org/10.1016/j.jhep.2022.08.035
https://doi.org/10.1016/j.jhep.2022.08.035
Autor:
Natalia Jiménez, Òscar Reig, Ruth Montalbo, Maria Milà-Guasch, Lluis Nadal-Dieste, Giancarlo Castellano, Juan José Lozano, Iván Victoria, Albert Font, Alejo Rodriguez-Vida, Joan Carles, Cristina Suárez, Montserrat Domènech, Núria Sala-González, Pedro Luis Fernández, Leonardo Rodríguez-Carunchio, Sherley Díaz, Aleix Prat, Mercedes Marín-Aguilera, Begoña Mellado
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The prostatic tumor cells plasticity is involved in resistance to hormone-therapy, allowing these cells to survive despite androgen receptor inhibition. However, its role in taxanes resistance has not been fully established. Gene expression of plasti
Externí odkaz:
https://doaj.org/article/726f1350f86d42a4828178363a9d8ed6
Autor:
Sebastià Franch-Expósito, Laia Bassaganyas, Maria Vila-Casadesús, Eva Hernández-Illán, Roger Esteban-Fabró, Marcos Díaz-Gay, Juan José Lozano, Antoni Castells, Josep Maria Llovet, Sergi Castellví-Bel, Jordi Camps
Publikováno v:
eLife, Vol 9 (2020)
Somatic copy number alterations (CNAs) are a hallmark of cancer, but their role in tumorigenesis and clinical relevance remain largely unclear. Here, we developed CNApp, a web-based tool that allows a comprehensive exploration of CNAs by using purity
Externí odkaz:
https://doaj.org/article/a0af249d134f486c9916e52fa1b83e3e
Autor:
Martí Ortega-Ribera, Albert Gibert-Ramos, Laia Abad-Jordà, Marta Magaz, Luis Téllez, Lorena Paule, Elisa Castillo, Raül Pastó, Bruno de Souza Basso, Pol Olivas, Lara Orts, Juan José Lozano, Rosa Villa, Jaime Bosch, Agustín Albillos, Joan Carles García-Pagán, Jordi Gracia-Sancho
Publikováno v:
Ortega-Ribera, Martí; Gibert-Ramos, Albert; Abad-Jordà, Laia; Magaz, Marta; Téllez, Luis; Paule, Lorena; Castillo, Elisa; Pastó, Raül; de Souza Basso, Bruno; Olivas, Pol; Orts, Lara; Lozano, Juan José; Villa, Rosa; Bosch, Jaime; Albillos, Agustín; García-Pagán, Joan Carles; Gracia-Sancho, Jordi (2023). Increased sinusoidal pressure impairs liver endothelial mechanosensing, uncovering novel biomarkers of portal hypertension. JHEP reports, 5(6), p. 100722. Elsevier 10.1016/j.jhepr.2023.100722
BACKGROUND & AIMS Portal hypertension (PH) is a frequent and severe clinical syndrome associated with chronic liver disease. Considering the mechanobiological effects of hydrostatic pressure and shear stress on endothelial cells, we hypothesised that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b2966fc3de887f2aeb63ef801d5279
https://boris.unibe.ch/182391/1/1-s2.0-S2589555923000538-main.pdf
https://boris.unibe.ch/182391/1/1-s2.0-S2589555923000538-main.pdf
