Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Juan Segura Aguilar"'
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 3, Pp 529-535 (2024)
The positive effect of levodopa in the treatment of Parkinson’s disease, although it is limited in time and has severe side effects, has encouraged the scientific community to look for new drugs that can stop the neurodegenerative process or even r
Externí odkaz:
https://doaj.org/article/ded20040041d47f681f4884efddbdfcf
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 673 (2024)
One of the biggest problems in the treatment of idiopathic Parkinson’s disease is the lack of new drugs that slow its progression. L-Dopa remains the star drug in the treatment of this disease, although it induces severe side effects. The failure o
Externí odkaz:
https://doaj.org/article/db213a531a6741dba54f45bb7c317735
Autor:
Victor Da Silva, Fillipe De Araújo, Cleonice Creusa Dos Santos, Jéssica Souza, Érica Soares, Lucas Matheus Gonçalves De Oliveira, Maria De Fátima Costa, Silvia Costa, Juan Segura-Aguilar, María-Trinidad Herrero
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S49-S50 (2023)
Externí odkaz:
https://doaj.org/article/6c48c51daddd4e0698057420f9e6e5e2
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 3094 (2023)
The transition metal characteristics of iron allow it to play a fundamental role in several essential aspects of human life such as the transport of oxygen through hemoglobin or the transport of electrons in the mitochondrial respiratory chain couple
Externí odkaz:
https://doaj.org/article/d8c0c7d09d2c41cea9576978f51c4869
Autor:
Juan Segura-Aguilar, Bengt Mannervik, José Inzunza, Mukesh Varshney, Ivan Nalvarte, Patricia Muñoz
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 9, Pp 1861-1866 (2022)
Astrocytes protect neurons by modulating neuronal function and survival. Astrocytes support neurons in several ways. They provide energy through the astrocyte-neuron lactate shuttle, protect neurons from excitotoxicity, and internalize neuronal lipid
Externí odkaz:
https://doaj.org/article/7b1d2a4e60d64753bef746c18035d9e4
Autor:
Juan Segura-Aguilar, Bengt Mannervik
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 673 (2023)
Investigations of the effect of antioxidants on idiopathic Parkinson’s disease have been unsuccessful because the preclinical models used to propose these clinical studies do not accurately represent the neurodegenerative process of the disease. Tr
Externí odkaz:
https://doaj.org/article/8245bb6d8123478fab2fbc5999a85e1a
Publikováno v:
Stem Cell Research, Vol 51, Iss , Pp 102193- (2021)
KISCOi001-A is a healthy feeder-free and fully characterized human induced pluripotent stem (iPS) cell line cultured under xeno-free and defined conditions. The cell line is generated from normal human foreskin fibroblasts with non-integrating episom
Externí odkaz:
https://doaj.org/article/5fafaa6bf96d49ac9d2a8ba7b1673841
Autor:
Fillipe Mendes De Araújo, Annyta F. Frota, Lívia B. de Jesus, Lorena Cuenca-Bermejo, Kariny Maria S. Ferreira, Cleonice Creusa Santos, Erica N. Soares, Jéssica T. Souza, Flávia S. Sanches, Ana Carla S. Costa, Alana A. Farias, Maria de Fatima Dias Costa, Patrícia Munoz, José A. Menezes-Filho, Juan Segura-Aguilar, Silvia Lima Costa, Maria Trinidad Herrero, Victor Diogenes Amaral Silva
Publikováno v:
Neurotoxicity Research. 41:224-241
Autor:
Juan Segura-Aguilar, Patricia Muñoz, Jose Inzunza, Mukesh Varshney, Ivan Nalvarte, Bengt Mannervik
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 296 (2022)
Glutathione is an important antioxidant that plays a crucial role in the cellular protection against oxidative stress and detoxification of electrophilic mutagens, and carcinogens. Glutathione transferases are enzymes catalyzing glutathione-dependent
Externí odkaz:
https://doaj.org/article/fd770e1abf2f4107ab85dfd93a25cd9b
Autor:
Victor Silva, Juan Segura-Aguilar
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 9, Pp 1797-1798 (2021)
Externí odkaz:
https://doaj.org/article/8f2db14e007046d7a030df077c5608af