Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Juan Sastre"'
Autor:
Mette Sørensen, Göran Pershagen, Jesse Daniel Thacher, Timo Lanki, Benedikt Wicki, Martin Röösli, Danielle Vienneau, Manuella Lech Cantuaria, Jesper Hvass Schmidt, Gunn Marit Aasvang, Sadeer Al-Kindi, Michael T. Osborne, Philip Wenzel, Juan Sastre, Ingrid Fleming, Rainer Schulz, Omar Hahad, Marin Kuntic, Jacek Zielonka, Helmut Sies, Tilman Grune, Katie Frenis, Thomas Münzel, Andreas Daiber
Publikováno v:
Redox Biology, Vol 69, Iss , Pp 102995- (2024)
Transportation noise is a ubiquitous urban exposure. In 2018, the World Health Organization concluded that chronic exposure to road traffic noise is a risk factor for ischemic heart disease. In contrast, they concluded that the quality of evidence fo
Externí odkaz:
https://doaj.org/article/9422ae74b23f4599bfc0b65004a7dfa1
Publikováno v:
Redox Biology, Vol 56, Iss , Pp 102423- (2022)
Mitochondrial dysfunction is a key contributor to necroptosis. We have investigated the contribution of p53, sulfiredoxin, and mitochondrial peroxiredoxin 3 to necroptosis in acute pancreatitis. Late during the course of pancreatitis, p53 was localiz
Externí odkaz:
https://doaj.org/article/d71847ce10d9441795afba84c3662fed
Autor:
Raúl González, María A. Rodríguez-Hernández, María Negrete, Kalina Ranguelova, Aurelie Rossin, Carmen Choya-Foces, Patricia de la Cruz-Ojeda, Antonio Miranda-Vizuete, Antonio Martínez-Ruiz, Sergio Rius-Pérez, Juan Sastre, José A. Bárcena, Anne-Odile Hueber, C. Alicia Padilla, Jordi Muntané
Publikováno v:
Redox Biology, Vol 34, Iss , Pp 101528- (2020)
Hepatocellular carcinoma (HCC) represents 80% of the primary hepatic neoplasms. It is the sixth most frequent neoplasm, the fourth cause of cancer-related death, and 7% of registered malignancies. Sorafenib is the first line molecular targeted therap
Externí odkaz:
https://doaj.org/article/a773d763af1a4f16b908e005722e555a
Autor:
Sergio Rius-Pérez, Salvador Pérez, Isabel Torres-Cuevas, Pablo Martí-Andrés, Raquel Taléns-Visconti, Alberto Paradela, Laura Guerrero, Luis Franco, Gerardo López-Rodas, Luis Torres, Fernando Corrales, Juan Sastre
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
Acute pancreatitis is an inflammatory process of the pancreatic gland that may lead to dysregulation of the trans-sulfuration pathway. The aims of this work were firstly to study the methionine cycle as well as the trans-sulfuration pathway using met
Externí odkaz:
https://doaj.org/article/397cc4b8d6884bd0bbebae27c8e5d23d
Autor:
Salvador Pérez, Sergio Rius-Pérez, Ana M. Tormos, Isabela Finamor, Ángel R. Nebreda, Raquel Taléns-Visconti, Juan Sastre
Publikováno v:
Redox Biology, Vol 16, Iss , Pp 276-284 (2018)
p38α is a redox sensitive MAPK activated by pro-inflammatory cytokines and environmental, genotoxic and endoplasmic reticulum stresses. The aim of this work was to assess whether p38α controls the antioxidant defense in the liver, and if so, to elu
Externí odkaz:
https://doaj.org/article/af101cae690c4f3fbbb762e9e4f8d37b
Autor:
Isabela Finamor, Salvador Pérez, Caroline A. Bressan, Carlos E. Brenner, Sergio Rius-Pérez, Patricia C. Brittes, Gabriele Cheiran, Maria I. Rocha, Marcelo da Veiga, Juan Sastre, Maria A. Pavanato
Publikováno v:
Redox Biology, Vol 11, Iss , Pp 701-707 (2017)
No-caloric sweeteners, such as aspartame, are widely used in various food and beverages to prevent the increasing rates of obesity and diabetes mellitus, acting as tools in helping control caloric intake. Aspartame is metabolized to phenylalanine, as
Externí odkaz:
https://doaj.org/article/ba3744167af541bfbfcc736c8aea2e30
Publikováno v:
Redox Biology, Vol 5, Iss , Pp 1-14 (2015)
Acute pancreatitis is an inflammatory process of the pancreatic gland that eventually may lead to a severe systemic inflammatory response. A key event in pancreatic damage is the intracellular activation of NF-κB and zymogens, involving also calcium
Externí odkaz:
https://doaj.org/article/afb5c71eb66b4c2590f3be9e3ae5ccc4
Autor:
Ana M Tormos, Sergio Rius-Pérez, María Jorques, Patricia Rada, Lorena Ramirez, Ángela M Valverde, Ángel R Nebreda, Juan Sastre, Raquel Taléns-Visconti
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171738 (2017)
BACKGROUND:Hepatocyte poliploidization is an age-dependent process, being cytokinesis failure the main mechanism of polyploid hepatocyte formation. Our aim was to study the role of p38α MAPK in the regulation of actin cytoskeleton and cytokinesis in
Externí odkaz:
https://doaj.org/article/a3631ffd8f07407d93dffb17cd17ef55
Autor:
Javier Escobar, Elena Cubells, Masahiro Enomoto, Guillermo Quintás, Julia Kuligowski, Cristina Martinez Fernández, Isabel Torres-Cuevas, Juan Sastre, Jaques Belik, Máximo Vento
Publikováno v:
Redox Biology, Vol 1, Iss 1, Pp 297-303 (2013)
Background: Fetal-to-neonatal transition is associated with oxidative stress. In preterm infants, immaturity of the antioxidant system favours supplemental oxygen-derived morbidity and mortality. Objectives: To assess if prolonging in utero-like oxyg
Externí odkaz:
https://doaj.org/article/bd47969de79b476a8a77c13daa5706d4
Autor:
Rønnaug Solberg, Javier Escobar, Alessandro Arduini, Isabel Torres-Cuevas, Agustín Lahoz, Juan Sastre, Ola Didrik Saugstad, Máximo Vento, Julia Kuligowski, Guillermo Quintás
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66540 (2013)
The availability of reliable biomarkers of brain injury secondary to birth asphyxia could substantially improve clinical grading, therapeutic intervention strategies, and prognosis. In this study, changes in the metabolome of retinal tissue caused by
Externí odkaz:
https://doaj.org/article/815c6dfa602245c0a71e84d47702fb7f