Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Juan R. Luque-Ortega"'
Autor:
Antonio Rodríguez-Blázquez, Arturo Carabias, Alba Morán-Vaquero, Sergio de Cima, Juan R. Luque-Ortega, Carlos Alfonso, Peter Schuck, José Antonio Manso, Sandra Macedo-Ribeiro, Carmen Guerrero, José M. de Pereda
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract Background C3G is a guanine nucleotide exchange factor (GEF) that activates Rap1 to promote cell adhesion. Resting C3G is autoinhibited and the GEF activity is released by stimuli that signal through tyrosine kinases. C3G is activated by tyr
Externí odkaz:
https://doaj.org/article/69835b309c8c4fcc8550fc5ffc4c0d4f
Autor:
Wilfried J. J. Meijer, D. Roeland Boer, Saúl Ares, Carlos Alfonso, Fernando Rojo, Juan R. Luque-Ortega, Ling Juan Wu
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Bacterial conjugation is the main horizontal gene transfer route responsible for the spread of antibiotic resistance, virulence and toxin genes. During conjugation, DNA is transferred from a donor to a recipient cell via a sophisticated channel conne
Externí odkaz:
https://doaj.org/article/4f174db42c914c8583975c4f1954bfba
Autor:
Andrés Miguel-Arribas, Jian-An Hao, Juan R. Luque-Ortega, Gayetri Ramachandran, Jorge Val-Calvo, César Gago-Córdoba, Daniel González-Álvarez, David Abia, Carlos Alfonso, Ling J. Wu, Wilfried J. J. Meijer
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Bacterial conjugation is the process by which a conjugative element (CE) is transferred horizontally from a donor to a recipient cell via a connecting pore. One of the first steps in the conjugation process is the formation of a nucleoprotein complex
Externí odkaz:
https://doaj.org/article/bb9c2c0e67c0414590190045e59274ce
Autor:
Asier Unciti-Broceta, Neil O. Carragher, Valerie G. Brunton, Bin-Zhi Qian, Margaret C. Frame, Mark J. Arends, Maria Lopalco, Christina Schoenherr, Henry Beetham, Craig Fraser, Juan R. Luque-Ortega, Rafael Contreras-Montoya, Alison F. Munro, Teresa Valero, Kenneth G. Macleod, Morwenna Muir, John C. Dawson, Xue-Feng Li, Emily R. Webb, Daniel Lietha, Carolin Temps
Supplementary Data from A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f536ea2ccfc4256e470e9896ed6057b
https://doi.org/10.1158/0008-5472.22428648.v1
https://doi.org/10.1158/0008-5472.22428648.v1
Autor:
Asier Unciti-Broceta, Neil O. Carragher, Valerie G. Brunton, Bin-Zhi Qian, Margaret C. Frame, Mark J. Arends, Maria Lopalco, Christina Schoenherr, Henry Beetham, Craig Fraser, Juan R. Luque-Ortega, Rafael Contreras-Montoya, Alison F. Munro, Teresa Valero, Kenneth G. Macleod, Morwenna Muir, John C. Dawson, Xue-Feng Li, Emily R. Webb, Daniel Lietha, Carolin Temps
Despite the approval of several multikinase inhibitors that target SRC and the overwhelming evidence of the role of SRC in the progression and resistance mechanisms of many solid malignancies, inhibition of its kinase activity has thus far failed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92e862f8d441136de23e083b6c89a273
https://doi.org/10.1158/0008-5472.c.6513090.v1
https://doi.org/10.1158/0008-5472.c.6513090.v1
Autor:
Adrián Merino-Salomón, Jonathan Schneider, Leon Babl, Jan-Hagen Krohn, Marta Sobrinos-Sanguino, Tillman Schäfer, Juan R. Luque-Ortega, Carlos Alfonso, Mercedes Jiménez, Marion Jasnin, German Rivas, Petra Schwille
In most bacteria, division depends on a cytoskeletal structure, the FtsZ ring, that functions as a scaffold to recruit additional proteins, with which it forms the machinery responsible for division, the divisome. The detailed architecture of the rin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abbf3b991970079e53997bbd5da6e62b
http://hdl.handle.net/10261/309139
http://hdl.handle.net/10261/309139
Autor:
Antonio Rodríguez-Blázquez, Arturo Carabias, Alba Morán-Vaquero, Sergio de Cima, Juan R. Luque-Ortega, Carlos Alfonso, Peter Schuck, José Antonio Manso, Sandra Macedo-Ribeiro, Carmen Guerrero, José M. de Pereda
Publikováno v:
Rodríguez-Blázquez, A, Carabias, A, Morán-Vaquero, A, de Cima, S, Luque-Ortega, J R, Alfonso, C, Schuck, P, Manso, J A, Macedo-Ribeiro, S, Guerrero, C & de Pereda, J M 2023, ' Crk proteins activate the Rap1 guanine nucleotide exchange factor C3G by segregated adaptor-dependent and-independent mechanisms ', Cell Communication and Signaling, vol. 21, 30 . https://doi.org/10.1186/s12964-023-01042-2
Background C3G is a guanine nucleotide exchange factor (GEF) that activates Rap1 to promote cell adhesion. Resting C3G is autoinhibited and the GEF activity is released by stimuli that signal through tyrosine kinases. C3G is activated by tyrosine pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd197d03a68cc847d778fd7df149efdc
https://doi.org/10.1101/2022.11.24.515150
https://doi.org/10.1101/2022.11.24.515150
Autor:
Wilfried J J, Meijer, D Roeland, Boer, Saúl, Ares, Carlos, Alfonso, Fernando, Rojo, Juan R, Luque-Ortega, Ling Juan, Wu
Publikováno v:
Frontiers in Molecular Biosciences
Bacterial conjugation is the main horizontal gene transfer route responsible for the spread of antibiotic resistance, virulence and toxin genes. During conjugation, DNA is transferred from a donor to a recipient cell via a sophisticated channel conne
Autor:
Andrés, Miguel-Arribas, Jian-An, Hao, Juan R, Luque-Ortega, Gayetri, Ramachandran, Jorge, Val-Calvo, César, Gago-Córdoba, Daniel, González-Álvarez, David, Abia, Carlos, Alfonso, Ling J, Wu, Wilfried J J, Meijer
Publikováno v:
Frontiers in Microbiology
Bacterial conjugation is the process by which a conjugative element (CE) is transferred horizontally from a donor to a recipient cell via a connecting pore. One of the first steps in the conjugation process is the formation of a nucleoprotein complex
Autor:
Angel, Rivera-Calzada, Mohinder, Pal, Hugo, Muñoz-Hernández, Juan R, Luque-Ortega, David, Gil-Carton, Gianluca, Degliesposti, J Mark, Skehel, Chrisostomos, Prodromou, Laurence H, Pearl, Oscar, Llorca
Publikováno v:
Structure(London, England:1993)
Summary The R2TP complex, comprising the Rvb1p-Rvb2p AAA-ATPases, Tah1p, and Pih1p in yeast, is a specialized Hsp90 co-chaperone required for the assembly and maturation of multi-subunit complexes. These include the small nucleolar ribonucleoproteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7b00cee474ac16562df588f5beb38063