Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Juan R. Acosta"'
Autor:
Juan R. Acosta, Simon Joost, Kasper Karlsson, Anna Ehrlund, Xidan Li, Myriam Aouadi, Maria Kasper, Peter Arner, Mikael Rydén, Jurga Laurencikiene
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-6 (2017)
Abstract Regulation of adipose tissue stem cells (ASCs) and adipogenesis impact the development of excess body fat-related metabolic complications. Animal studies have suggested the presence of distinct subtypes of ASCs with different differentiation
Externí odkaz:
https://doaj.org/article/6b3adb523481403fa689ec1e398a945a
Autor:
Paul Petrus, Niklas Mejhert, Patricia Corrales, Simon Lecoutre, Qian Li, Estela Maldonado, Agne Kulyté, Yamila Lopez, Mark Campbell, Juan R. Acosta, Jurga Laurencikiene, Iyadh Douagi, Hui Gao, Concepción Martínez-Álvarez, Per Hedén, Kirsty L. Spalding, Antonio Vidal-Puig, Gema Medina-Gomez, Peter Arner, Mikael Rydén
Publikováno v:
Cell Reports, Vol 25, Iss 3, Pp 551-560.e5 (2018)
Summary: White adipose tissue (WAT) mass is determined by adipocyte size and number. While adipocytes are continuously turned over, the mechanisms controlling fat cell number in WAT upon weight changes are unclear. Herein, prospective studies of huma
Externí odkaz:
https://doaj.org/article/9419d552f02b4179bebb20837d864c38
Autor:
Agné Kulyté, Jurga Laurencikiene, Juan R. Acosta, Beatriz Tavira, Mikael Rydén, Iyadh Douagi, Peter Arner
Publikováno v:
The Journal of clinical endocrinology and metabolism. 104(10)
Objective Although IL-10 is generally considered as an anti-inflammatory cytokine, it was recently shown to have detrimental effects on insulin sensitivity and fat cell metabolism in rodents. Whether this also pertains to human white adipose tissue (
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
Context: The adipokines chemerin, dipeptidyl peptidase 4, and adiponectin influence insulin sensitivity. Whether their circulating levels and adipose secretion are altered in nonobese individuals with type 2 diabetes mellitus (T2DM) is unknown. Objec
Autor:
Peter Arner, Ingrid Dahlman, Erik Näslund, Jesper Bäckdahl, Anna Ehrlund, Mikael Rydén, Jurga Laurencikiene, Agné Kulyté, Daniel Eriksson Hogling, Hui Gao, Niklas Mejhert, Juan R. Acosta, Daniel P. Andersson, Paul Petrus
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 101:4021-4029
Context: Cardiometabolic complications in obesity may be linked to white adipose tissue (WAT) dysfunction. Transcriptomic studies of Sc WAT have reported that CCL18, encoding the CC chemokine ligand 18 (CCL18), is increased in obesity/insulin resista
Autor:
Juan R. Acosta, Daniel P. Andersson, Jesper Bäckdahl, Jurga Laurencikiene, Iyadh Douagi, Peter Arner, Mikael Rydén
Publikováno v:
Diabetologia. 59:560-570
We aimed to elucidate the impact of fat cell size and inflammatory status of adipose tissue on the development of type 2 diabetes in non-obese individuals. We characterised subcutaneous abdominal adipose tissue by examining stromal cell populations b
Autor:
Mengyin Cai, Leif Groop, David Atac, Markku Laakso, Yang De Marinis, Pradeep Bompada, Albert Salehi, Juan R. Acosta, Rashmi B. Prasad
Osteopontin (OPN) is involved in various physiological processes and also implicated in multiple pathological states. It has been suggested that OPN may have a role in type 2 diabetes (T2D) by protecting pancreatic islets and interaction with increti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87acfa9c8c0218bd4575dc970c7ec2b0
http://hdl.handle.net/10138/299382
http://hdl.handle.net/10138/299382
Autor:
Mikael Rydén, Myriam Aouadi, Simon Joost, Peter Arner, Maria Kasper, Jurga Laurencikiene, Juan R. Acosta, Xidan Li, Kasper Karlsson, Anna Ehrlund
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-6 (2017)
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-6 (2017)
Regulation of adipose tissue stem cells (ASCs) and adipogenesis impact the development of excess body fat-related metabolic complications. Animal studies have suggested the presence of distinct subtypes of ASCs with different differentiation properti
Autor:
Anna Ehrlund, Peter Arner, Jurga Laurencikiene, Per Hedén, Iyadh Douagi, Christel Björk, Juan R. Acosta
Publikováno v:
Scientific Data
Obesity affects gene expression and metabolism of white adipose tissue (WAT), which results in insulin resistance (IR) and type 2 diabetes. However, WAT is a heterogeneous organ containing many cell types that might respond differently to obesity-ind
Autor:
Concepción Martínez-Álvarez, Antonio Vidal-Puig, Paul Petrus, Juan R. Acosta, Gema Medina-Gómez, Jurga Laurencikiene, Per Hedén, Mikael Rydén, Qian Li, Kirsty L. Spalding, Simon Lecoutre, Estela Maldonado, Peter Arner, Agné Kulyté, Niklas Mejhert, Yamila López, Hui Gao, Iyadh Douagi, Patricia Corrales, Mark Campbell
Publikováno v:
Cell Reports, Vol 25, Iss 3, Pp 551-560.e5 (2018)
Summary: White adipose tissue (WAT) mass is determined by adipocyte size and number. While adipocytes are continuously turned over, the mechanisms controlling fat cell number in WAT upon weight changes are unclear. Herein, prospective studies of huma