Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Juan Pina-Crespo"'
Autor:
Shu-ichi Okamoto, Olga Prikhodko, Juan Pina-Crespo, Anthony Adame, Scott R. McKercher, Laurence M. Brill, Nobuki Nakanishi, Chang-ki Oh, Tomohiro Nakamura, Eliezer Masliah, Stuart A. Lipton
Publikováno v:
Neurobiology of Disease, Vol 127, Iss , Pp 390-397 (2019)
Tuberous sclerosis (TSC) is an autosomal dominant disorder caused by heterozygous mutations in the TSC1 or TSC2 gene. TSC is often associated with neurological, cognitive, and behavioral deficits. TSC patients also express co-morbidity with anxiety a
Externí odkaz:
https://doaj.org/article/a572bd40338d4b15b09c31e72f6e65cb
Autor:
Bing Zhu, Yan Liu, Spring Hwang, Kailey Archuleta, Huijie Huang, Alex Campos, Rabi Murad, Juan Piña-Crespo, Huaxi Xu, Timothy Y. Huang
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-24 (2022)
Abstract Background Alzheimer’s disease (AD) is a neurodegenerative disorder that manifests sequential Aβ and tau brain pathology with age-dependent onset. Variants in the microglial immune receptor TREM2 are associated with enhanced risk of onset
Externí odkaz:
https://doaj.org/article/0541d50ee2fb468380405e80ced1fc80
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-11 (2019)
Abstract Alzheimer’s disease (AD) is an aging-related neurological disorder characterized by synaptic loss and dementia. Wnt/β-catenin signaling is an essential signal transduction pathway that regulates numerous cellular processes including cell
Externí odkaz:
https://doaj.org/article/6550cea85bf24f87b175d5c864ef8368
Publikováno v:
Chinese Medical Journal, Vol 130, Iss 24, Pp 2978-2990 (2017)
Objective: To review recent research advances on tau, a major player in Alzheimer's disease (AD) pathogenesis, a biomarker for AD onset, and potential target for AD therapy. Data Sources: This review was based on a comprehensive search using online l
Externí odkaz:
https://doaj.org/article/309a97328427420cb646bc2c8ff4fdd0
Autor:
Lu-Lin Jiang1, Bing Zhu1, Yingjun Zhao1, Xiaoguang Li1, Tongfei Liu1, Juan Pina-Crespo1, Lisa Zhou1, Wenxi Xu2, Rodriguez, Maria J.3,4, Haiyang Yu5, Cleveland, Don W.3,5,6, Ravits, John3,4, Da Cruz, Sandrine5, Tao Long2, Dongxian Zhang1, Huang, Timothy Y.1, Huaxi Xu1 xuh@sbpdiscovery.org, Jiang, Lu-Lin1 (AUTHOR), Zhu, Bing1 (AUTHOR), Zhao, Yingjun1 (AUTHOR)
Publikováno v:
Journal of Clinical Investigation. Aug2019, Vol. 129 Issue 8, p3103-3120. 18p.