Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Juan Pedro Martinez Barbera"'
Autor:
John R. Apps, Jose Mario Gonzalez-Meljem, Romain Guiho, Jessica C. Pickles, Eric Prince, Edward Schwalbe, Nikhil Joshi, Thomas J. Stone, Olumide Ogunbiyi, Jane Chalker, Akang Bassey, Georg Otto, Rosalind Davies, Debbie Hughes, Sebastian Brandner, Enrica Tan, Victoria Lee, Caroline Hayhurst, Cassie Kline, Sergi Castellano, Todd Hankinson, Timo Deutschbein, Thomas S. Jacques, Juan Pedro Martinez-Barbera
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-15 (2024)
Abstract The two types of craniopharyngioma, adamantinomatous (ACP) and papillary (PCP), are clinically relevant tumours in children and adults. Although the biology of primary craniopharyngioma is starting to be unravelled, little is known about the
Externí odkaz:
https://doaj.org/article/0874ef81d5794b778ecf6f36f0dcbfe2
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104905- (2024)
Summary: The long-standing view of senescent cells as passive and dysfunctional biological remnants has recently shifted into a new paradigm where they are main players in the development of many diseases, including cancer. The senescence programme r
Externí odkaz:
https://doaj.org/article/2dc06404e7b54feabdeb0853affa06b7
Autor:
Jose Mario Gonzalez-Meljem, Sarah Ivins, Cynthia Lilian Andoniadou, Paul Le Tissier, Peter Scambler, Juan Pedro Martinez-Barbera
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0280001 (2023)
The chemokine SDF-1 (CXCL12) and its receptor CXCR4 control several processes during embryonic development such as the regulation of stem cell proliferation, differentiation, and migration. However, the role of this pathway in the formation of the pi
Externí odkaz:
https://doaj.org/article/60e7db68dcd349edb05899958a92d033
Autor:
Sara Pozzi, Sarah Bowling, John Apps, Joshua M. Brickman, Tristan A. Rodriguez, Juan Pedro Martinez-Barbera
Publikováno v:
Stem Cell Reports, Vol 13, Iss 6, Pp 970-979 (2019)
Summary: The role of the homeobox transcriptional repressor HESX1 in embryonic stem cells (ESCs) remains mostly unknown. Here, we show that Hesx1 is expressed in the preimplantation mouse embryo, where it is required during developmental diapause. Ab
Externí odkaz:
https://doaj.org/article/2f08bd3583ac4b439257b27bdcbe40cf
Autor:
John Richard Apps, Hermann Lothar Muller, Todd Cameron Hankinson, Torunn Ingrid Yock, Juan Pedro Martinez-Barbera
Publikováno v:
Endocrine Reviews. 44:518-538
Craniopharyngiomas are clinically aggressive tumours due to their invasive behaviour and recalcitrant tendency to recur after therapy. There are two types based on their distinct histology and molecular features: The papillary craniopharyngioma (PCP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7cf44b141d32e51863820d6e40dace9
https://doi.org/10.1210/endrev/bnac035
https://doi.org/10.1210/endrev/bnac035
Autor:
Sarah Bowling, Aida Di Gregorio, Margarida Sancho, Sara Pozzi, Marieke Aarts, Massimo Signore, Michael D. Schneider, Juan Pedro Martinez-Barbera, Jesús Gil, Tristan A. Rodríguez
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
During embryo development, cell fitness determines survival but how this is regulated is unclear. Here, the authors show that in early embryonic development and stem cells exiting the naive state, cells sense the fitness of their neighbours and trigg
Externí odkaz:
https://doaj.org/article/fa84dfb29e394c458e23e23541902818
Autor:
Jose Mario Gonzalez-Meljem, Scott Haston, Gabriela Carreno, John R. Apps, Sara Pozzi, Christina Stache, Grace Kaushal, Alex Virasami, Leonidas Panousopoulos, Seyedeh Neda Mousavy-Gharavy, Ana Guerrero, Mamunur Rashid, Nital Jani, Colin R. Goding, Thomas S. Jacques, David J. Adams, Jesus Gil, Cynthia L. Andoniadou, Juan Pedro Martinez-Barbera
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Senescent cells can promote tumour progression through the activation of a senescenceassociated secretory phenotype (SASP). Here, the authors show that SASP activation is associated with non-cell autonomous cell transformation and tumour initiation i
Externí odkaz:
https://doaj.org/article/a0474958863a4634a3e1c6faf8951dc5
Autor:
John R. Apps, J. Ciaran Hutchinson, Susan Shelmerdine, Alex Virasami, Eduard Winter, Thomas S. Jacques, Juan-Pedro Martinez-Barbera, Owen Arthurs, Thomas Czech
Publikováno v:
F1000Research, Vol 8 (2019)
This manuscript describes the study of two cases of craniopharyngioma, which have been examined repeatedly over three separate centuries. This includes analysis by Josef Engel in 1839, who sought to uncover the physiological role of the pituitary gla
Externí odkaz:
https://doaj.org/article/e1f70f2e62ee42b18c173a2382433568
Autor:
Juan Pedro Martinez-Barbera, Saba Manshaei, Thea Willis, Virinder Reen, Hussayn Pallikonda, Dominic Withers, Jesus Gil, Cynthia Andoniadou
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9657a88a4f0f8ca81d076254b8280c30
https://doi.org/10.1530/endoabs.90.oc7.2
https://doi.org/10.1530/endoabs.90.oc7.2
Autor:
Alvaro Flores-Martinez, Antonio C. Fuentes-Fayos, Miguel E. G-Garcia, David Cano Gonzales, Isidoro Di Caro, Martinez-Fuentes Antonio Jesus, Justo P. Castano, Manuel D. Gahete, Juan Pedro Martinez-Barbera, Alfonso Soto-Moreno, Galvez-Moreno Maria Angeles, Raul M Luque
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::377feddd7a01791182a494544c9b7b99
https://doi.org/10.1530/endoabs.90.oc7.6
https://doi.org/10.1530/endoabs.90.oc7.6