Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Juan Pablo Unfried"'
Autor:
Sara De Bragança, Clara Aicart-Ramos, Raquel Arribas-Bosacoma, Angel Rivera-Calzada, Juan Pablo Unfried, Laura Prats-Mari, Mikel Marin-Baquero, Puri Fortes, Oscar Llorca, Fernando Moreno-Herrero
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111917- (2023)
Summary: The synapsis of DNA ends is a critical step for the repair of double-strand breaks by non-homologous end joining (NHEJ). This is performed by a multicomponent protein complex assembled around Ku70-Ku80 heterodimers and regulated by accessory
Externí odkaz:
https://doaj.org/article/bdd06c938e2c4905878ed00d980ca5c2
Autor:
Marina Barriocanal, Laura Prats-Mari, Nerea Razquin, Celia Prior, Juan Pablo Unfried, Puri Fortes
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The study of the interferon (IFN) α-induced cell transcriptome has shown altered expression of several long non-coding RNAs (lncRNAs). ISR8/IRF1-AS1 (IFN stimulated RNA 8), located close to IFN regulatory factor 1 (IRF1) coding gene, transcribes a l
Externí odkaz:
https://doaj.org/article/0b1e61682eaa4ba6b268614f84c67a21
Autor:
Juan Pablo Unfried, Igor Ulitsky
Publikováno v:
Nature Cell Biology. 24:608-615
Low expression levels and stoichiometric imbalances of long noncoding RNAs (lncRNAs) are often used as evidence for their probable lack of function or for limiting the scope of their potential influence. Recent advances in our understanding of the su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc8cb00cf0ff92fd25976bf8a00c42d
https://doi.org/10.1038/s41556-022-00911-1
https://doi.org/10.1038/s41556-022-00911-1
Autor:
John L Rinn, Edward B. Chuong, Mark W. Feinberg, Junchao Shi, Jennifer Cable, Erwei Song, Matthew D. Simon, Qi Chen, Howard Y. Chang, Anna Marie Pyle, Sofia A. Quinodoz, Chun-Kan Chen, Edith Heard, Jonathan E. Henninger, Amanda E. Hargrove, Dhiraj Kumar, Jeremy E. Wilusz, Rory Johnson, Marco Marcia, Adelheid Lempradl, David L. Spector, Kannanganattu V. Prasanth, Joshua T. Mendell, Juan Pablo Unfried, Samie R. Jaffrey, Allison M Porman, Sean E. McGeary, Mukesh Kumar Lalwani, Murat C. Kalem, Ling-Ling Chen, Xuhang Liu, Tetsuro Hirose, Roza K. Przanowska, Xiaohua Shen, Lamia Wahba, Lin He, Sarah D. Diermeier, Lydia M. Contreras, Lynne E. Maquat
Publikováno v:
Ann N Y Acad Sci
The human transcriptome contains many types of noncoding RNAs, which rival the number of protein-coding species. From long noncoding RNAs (lncRNAs) that are over 200 nucleotides long to piwi-interacting RNAs (piRNAs) of only 20 nucleotides, noncoding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b7e926c06d071808b4c085a712113a
https://doi.org/10.1111/nyas.14713
https://doi.org/10.1111/nyas.14713
Autor:
Juan Pablo Unfried, Mehrdad Izadirad, Zhe-Sheng Chen, Leila Jafari, Alva Rani James, Zhuo-Xun Wu
Publikováno v:
Drug Discovery Today. 26:1735-1743
Many patients with acute myeloid leukemia (AML) experience poor outcomes following traditional high-dose chemotherapies and complete remission rates remain suboptimal. Chemoresistance is an obstacle to effective chemotherapy and the precise mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3aece59cc184f2da873ea4284df6abf
https://doi.org/10.1016/j.drudis.2021.03.017
https://doi.org/10.1016/j.drudis.2021.03.017
Autor:
Miriam Recalde, María Gárate-Rascón, José María Herranz, María Elizalde, María Azkona, Juan Pablo Unfried, Bruno Sangro, Maite G Fernandez-Barrena, Puri Fortes, Matías A Avila, Carmen Berasain, Maria Arechederra
Publikováno v:
Journal of Hepatology. 77:S644-S645
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b0436a346d1c00724a94ea30d431f49
https://doi.org/10.1016/s0168-8278(22)01604-x
https://doi.org/10.1016/s0168-8278(22)01604-x
Autor:
Bruno Sangro, Christopher McCoy, Puri Fortes, Fernando Moreno-Herrero, Linda Lee, Sara de Bragança, Susan P. Lees-Miller, Oscar Llorca, Juan Pablo Unfried, Clara Aicart-Ramos, Gareth J. Williams, Laura Prats-Mari, Eva María Martín-Cuevas, Raquel Arribas-Bosacoma, Stefano Caruso, Angel Rivera-Calzada, Jessica Zucman-Rossi, Nerea Razquin, Mikel Marin-Baquero
Publikováno v:
Cancer Res
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cancer Research
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cancer Research
[Abstract] Long noncoding RNAs (lncRNA) are emerging as key players in cancer as parts of poorly understood molecular mechanisms. Here, we investigated lncRNAs that play a role in hepatocellular carcinoma (HCC) and identified NIHCOLE, a novel lncRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cae90efa1b6096c29d3ead27e258865
https://europepmc.org/articles/PMC8488005/
https://europepmc.org/articles/PMC8488005/
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6447, p 6447 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The proper functioning of the immune system requires a robust control over a delicate equilibrium between an ineffective response and immune overactivation. Poor responses to viral insults may lead to chronic or overwhelming infection, whereas unrest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7804f20bbb1e5bb2b297da29031701f
https://www.mdpi.com/1422-0067/21/17/6447
https://www.mdpi.com/1422-0067/21/17/6447
Autor:
Juan Pablo Unfried, Puri Fortes
Publikováno v:
Journal of hepatology. 73(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41dc2ab544c6f0400c615d9b0d96166d
https://pubmed.ncbi.nlm.nih.gov/32461121
https://pubmed.ncbi.nlm.nih.gov/32461121
Autor:
Ainhoa Goñi-Salaverri, Jose A. Rodriguez, Nicholas D Weber, Juan Pablo Unfried, Josepmaria Argemi, not provided not provided, David Lara Astiaso
The COVID-19 pandemic has presented an unprecedent challenge to develop and validate testing tools for urgent disease diagnosis. Current testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) via molecular diagnostics is woefully in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6494f6e36e3c420ae42290c5bf27799
https://doi.org/10.17504/protocols.io.bfmajk2e
https://doi.org/10.17504/protocols.io.bfmajk2e