Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Juan Pablo Nicola"'
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/668c22b504394e189b061ca6a3afd289
Publikováno v:
Molecular Therapy: Oncolytics, Vol 28, Iss , Pp 44-45 (2023)
Externí odkaz:
https://doaj.org/article/bb7fe7521be34f138c0e96575ded8002
Autor:
Romina Celeste Geysels, Carlos Eduardo Bernal Barquero, Mariano Martín, Victoria Peyret, Martina Nocent, Gabriela Sobrero, Liliana Muñoz, Malvina Signorino, Graciela Testa, Ricardo Belisario Castro, Ana María Masini-Repiso, Mirta Beatriz Miras, Juan Pablo Nicola
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundCongenital iodide transport defect (ITD) is an uncommon cause of dyshormonogenic congenital hypothyroidism characterized by the absence of active iodide accumulation in the thyroid gland. ITD is an autosomal recessive disorder caused by los
Externí odkaz:
https://doaj.org/article/48789212a11540bc9e817a0526e34302
Autor:
Luz Maria Palacios, Victoria Peyret, María Estefania Viano, Romina Celeste Geysels, Yair Aron Chocobar, Ximena Volpini, Claudia Gabriela Pellizas, Juan Pablo Nicola, Claudia Cristina Motran, María Cecilia Rodriguez-Galan, Laura Fozzatti
Publikováno v:
Biology, Vol 11, Iss 11, p 1609 (2022)
Anaplastic thyroid cancer (ATC) is a clinically aggressive form of undifferentiated thyroid cancer with limited treatment options. Immunotherapy for patients with ATC remains challenging. Tumor-associated macrophages (TAMs) constitute over 50% of ATC
Externí odkaz:
https://doaj.org/article/6e91726b44be44a2b12cb95d6b42f199
Autor:
Pablo Di Giusto, Mariano Martín, Macarena Funes Chabán, Luciana Sampieri, Juan Pablo Nicola, Cecilia Alvarez
Publikováno v:
Cells, Vol 11, Iss 8, p 1314 (2022)
The transcription factor CREB3L1 is expressed in a wide variety of tissues including cartilage, pancreas, and bone. It is located in the endoplasmic reticulum and upon stimulation is transported to the Golgi where is proteolytically cleaved. Then, th
Externí odkaz:
https://doaj.org/article/50444fc2be6840138ec20e941aa0b0a8
Autor:
Luciana Noemi García, Carolina Leimgruber, Juan Pablo Nicola, Amado Alfredo Quintar, Cristina Alicia Maldonado
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0226233 (2020)
Allergic asthma is the most common phenotype of the pathology, having an early-onset in childhood and producing a Th2-driven airways remodeling process that leads to symptoms and pathophysiological changes. The avoidance of aeroallergen exposure in e
Externí odkaz:
https://doaj.org/article/ad1e5f10c5964d17a17800af130c4278
Autor:
Silvia Ravera, Juan Pablo Nicola, Glicella Salazar-De Simone, Fred J. Sigworth, Erkan Karakas, L. Mario Amzel, Mario A. Bianchet, Nancy Carrasco
Publikováno v:
Nature. 612:795-801
The sodium/iodide symporter (NIS) is the essential plasma membrane protein that mediates active iodide (I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c373fb87b1012b04f32fda3437fd80b4
https://doi.org/10.1038/s41586-022-05530-2
https://doi.org/10.1038/s41586-022-05530-2
Autor:
Carlos P. Modenutti, Ana María Masini-Repiso, Victoria Peyret, Gabriela Coux, Liliana Muñoz, Juan Pablo Nicola, Mariano Martín, Mirta Miras, Mauco Lucas Gil Rosas, Nora B. Calcaterra, Nancy Carrasco, Romina Celeste Geysels, Graciela Testa, Gabriela Sobrero, Carlos Eduardo Bernal Barquero, Marcelo A. Martí, Malvina Signorino
Publikováno v:
J Clin Endocrinol Metab
Context Iodide transport defect (ITD) (Online Mendelian Inheritance in Man No. 274400) is an uncommon cause of dyshormonogenic congenital hypothyroidism due to loss-of-function variants in the SLC5A5 gene, which encodes the sodium/iodide symporter (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9172eddb540ebed457d1fba818d3f123
https://doi.org/10.1210/clinem/dgab283
https://doi.org/10.1210/clinem/dgab283
Autor:
Silvia Ravera, Juan Pablo Nicola, Glicella Salazar de Simone, Fred J. Sigworth, Erkan Karakas, L. Mario Amzel, Mario A. Bianchet, Nancy Carrasco
The sodium/iodide symporter (NIS) is the essential plasma membrane protein that mediates active iodide (I-) transport into the thyroid gland, the first step in the biosynthesis of the thyroid hormones—the master regulators of intermediary metabolis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee24c6ca0623d121f6221c84f656a217
https://doi.org/10.1101/2022.04.07.487502
https://doi.org/10.1101/2022.04.07.487502
Autor:
Ana Chiesa, Patricia Papendieck, Ana María Masini-Repiso, Carlos Eduardo Bernal Barquero, Romina Celeste Geysels, Juan Pablo Nicola, Mariano Martín, Victoria Peyret
Publikováno v:
Thyroid.
BACKGROUND The sodium/iodide symporter (NIS) mediates active iodide accumulation in the thyroid follicular cell. Autosomal recessive iodide transport defect (ITD)-causing loss-of-function NIS variants lead to dyshormonogenic congenital hypothyroidism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0627ae01ac287ae453296d90ba96f9eb
https://doi.org/10.1089/thy.2021.0344
https://doi.org/10.1089/thy.2021.0344