Human macrophage polarization shapes B. pertussis intracellular persistence

Autor: Juan Pablo Gorgojo, Marcelo Fernandez Lahore, María Eugenia Rodríguez, José Luis Marín Franco, Luciana Balboa, María del Carmen Sasiain, Jimena Alvarez Hayes, Hugo A. Valdez

Publikováno v: Journal of Leukocyte Biology. 112:173-184

We previously demonstrated that Bordetella pertussis, the etiologic agent of whooping cough, is able to survive inside human macrophages. The aim of this study was to examine the influence of macrophage polarization in the development of B. pertussis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a382499b359223ebe4eaac85972204
https://doi.org/10.1002/jlb.4a0521-254r

Junin Virus Triggers Macrophage Activation and Modulates Polarization According to Viral Strain Pathogenicity

Autor: Aída Oryza López Ortiz, Víctor Romanowski, Andrea E. Errasti, Juan Pablo Gorgojo, María Florencia Ferrer, Eugenio Antonio Carrera Silva, Ricardo Martín Gómez, María Eugenia Rodríguez, Pablo Javier Thomas, Nancy Charo

Publikováno v: Frontiers in Immunology, Vol 10 (2019)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Frontiers in Immunology
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

The New World arenavirus Junin (JUNV) is the etiological agent of Argentine hemorrhagic fever (AHF). Previous studies of human macrophage infection by the Old-World arenaviruses Mopeia and Lassa showed that while the non-pathogenic Mopeia virus repli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32607f60f886d5b42fe5ed6fede99a08
https://www.frontiersin.org/article/10.3389/fimmu.2019.02499/full

Fibrillar conformation of an apolipoprotein A-I variant involved in amyloidosis and atherosclerosis

Autor: Eduardo Daniel Prieto, M. Fernanda Cortez, Romina A. Gisonno, M. Eugenia Rodriguez, Nahuel A. Ramella, M. Alejandra Tricerri, Juan Pablo Gorgojo, Lucrecia María Curto, Silvana Antonia Rosu, Gabriela Sandra Finarelli, Guillermo Raúl Schinella, Gisela M. Gaddi

Publikováno v: Biochimica et biophysica acta. General subjects. 1864(4)

Background Different protein conformations may be involved in the development of clinical manifestations associated with human amyloidosis. Although a fibrillar conformation is usually the signature of damage in the tissues of patients, it is not cle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c283b71c5a8ca28fd2551571f19abe
https://pubmed.ncbi.nlm.nih.gov/31904503

Bordetella parapertussis Circumvents Neutrophil Extracellular Bactericidal Mechanisms

Autor: Eric T. Harvill, María Eugenia Rodríguez, Ricardo Martín Gómez, Juan Pablo Gorgojo, Emilia Scharrig

Publikováno v: PLoS ONE
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE, Vol 12, Iss 1, p e0169936 (2017)

B. parapertussis is a whooping cough etiological agent with the ability to evade the immune response induced by pertussis vaccines. We previously demonstrated that in the absence of opsonic antibodies B. parapertussis hampers phagocytosis by neutroph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8d7266a2f04f993f7a3e98caa6b84f
http://europepmc.org/articles/PMC5240980

Bordetella parapertussis Survives inside Human Macrophages in Lipid Raft-Enriched Phagosomes

Autor: Juan Pablo Gorgojo, Eric T. Harvill, María Eugenia Rodríguez

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

Bordetella parapertussis is a human pathogen that causes whooping cough. The increasing incidence of B. parapertussis has been attributed to the lack of cross protection induced by pertussis vaccines. It was previously shown that B. parapertussis is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bbff1dd0c86029012f3778a9e0a9795
http://iai.asm.org/content/82/12/5175