Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Juan P. Hinestrosa"'
Autor:
Juan Pablo Hinestrosa, Rosalie C. Sears, Harmeet Dhani, Jean M. Lewis, Gregor Schroeder, Heath I. Balcer, Dove Keith, Brett C. Sheppard, Razelle Kurzrock, Paul R. Billings
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-9 (2023)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) has an overall 5-year survival rate of just 12.5% and thus is among the leading causes of cancer deaths. When detected at early stages, PDAC survival rates improve substantially. Testing hig
Externí odkaz:
https://doaj.org/article/5e4d29b135ed4bf3b420bb53eeb82566
Autor:
Harmeet Dhani, Juan Pablo Hinestrosa, Jesus Izaguirre-Carbonell, Heath I. Balcer, Razelle Kurzrock, Paul R. Billings
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThe detection of pancreatic ductal adenocarcinoma (PDAC) lesions at pre-cancerous or early-stages is critical to improving patient survival. We have developed a liquid biopsy test (ExoVita®) based on the measurement of protein biomarkers i
Externí odkaz:
https://doaj.org/article/72fc2aed76b04bef84dab9efa7bced5f
Autor:
Juan Pablo Hinestrosa, Razelle Kurzrock, Jean M. Lewis, Nicholas J. Schork, Gregor Schroeder, Ashish M. Kamat, Andrew M. Lowy, Ramez N. Eskander, Orlando Perrera, David Searson, Kiarash Rastegar, Jake R. Hughes, Victor Ortiz, Iryna Clark, Heath I. Balcer, Larry Arakelyan, Robert Turner, Paul R. Billings, Mark J. Adler, Scott M. Lippman, Rajaram Krishnan
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-9 (2022)
Hinestrosa et al. describe the early-stage detection of cancer using biomarkers present in circulating extracellular vesicles purified via an alternating current electrokinetics platform. They show, in a case-control study, that 95.7% of pancreatic,
Externí odkaz:
https://doaj.org/article/1d42a6ac983a4da48a2fb210e7baba4d
Autor:
Juan Pablo Hinestrosa, David J. Searson, Jean M. Lewis, Alfred Kinana, Orlando Perrera, Irina Dobrovolskaia, Kevin Tran, Robert Turner, Heath I. Balcer, Iryna Clark, David Bodkin, Dave S. B. Hoon, Rajaram Krishnan
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
The power of personalized medicine is based on a deep understanding of cellular and molecular processes underlying disease pathogenesis. Accurately characterizing and analyzing connections between these processes is dependent on our ability to access
Externí odkaz:
https://doaj.org/article/e98053a2e0944dbe9864d38d8bb3d1f6
Autor:
Juan P. Hinestrosa, Harmeet Dhani, Gregor Schroeder, Jean M. Lewis, Heath I. Balcer, Razelle Kurzrock, Dove Keith, Rosalie Sears, Paul Billings
Publikováno v:
Cancer Research. 83:6515-6515
Introduction Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer and is one of the deadliest cancer in the U.S., with a 5-year survival rate of just 11%. It is expected that ~62,000 new cases will be diagnosed in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac0aef449192e093575b6f555a9e9e71
https://doi.org/10.1158/1538-7445.am2023-6515
https://doi.org/10.1158/1538-7445.am2023-6515
Autor:
Juan P. Hinestrosa, Harmeet Dhani, Jean M. Lewis, Gregor K. Schroeder, Heath I. Balcer, Razelle Kurzrock, Paul Billings
Publikováno v:
Cancer Research. 83:6514-6514
Background Liquid biopsy approaches for lung cancer are becoming increasingly common for diagnosis, prognosis, and management of the disease. Of the Approximately 236K new lung cancer cases that will be diagnosed in 2023, over 70% of those will be re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7d240a9d3cfd2d19145f359dcaa6da2
https://doi.org/10.1158/1538-7445.am2023-6514
https://doi.org/10.1158/1538-7445.am2023-6514
Autor:
Juan P. Hinestrosa, Jean M. Lewis, David J. Searson, Heath I. Balcer, David J. Gonzalez, Rajaram Krishnan
Publikováno v:
Cancer Research. 82:5082-5082
In this study, we evaluated the ability to detect novel proteins on extracellular vesicles (EVs) following isolation using an alternating current electrokinetic (ACE) microarray. EVs circulating in blood contain a wealth of biomarkers that are though
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::466e51fc458de181a96529a40b6db6b1
https://doi.org/10.1158/1538-7445.am2022-5082
https://doi.org/10.1158/1538-7445.am2022-5082
Autor:
Juan P. Hinestrosa, Jean M. Lewis, Heath I. Balcer, Razelle Kurzrock, Scott Lippman, Rajaram Krishnan
Publikováno v:
Cancer Research. 82:5960-5960
Pancreatic cancer is an almost uniformly lethal malignancy, in large part because is it rarely detected in its early, curable stages. We recently conducted a study to evaluate the use of proteins associated with extracellular vesicles (EVs) isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd691e0ff586fe1741584400997c6b57
https://doi.org/10.1158/1538-7445.am2022-5960
https://doi.org/10.1158/1538-7445.am2022-5960
Autor:
Juan P. Hinestrosa, Jean M. Lewis, Gregor Schroder, Heath I. Balcer, Razelle Kurzrock, Rajaram Krishnan
Publikováno v:
Cancer Research. 82:727-727
We have recently conducted a study to evaluate the use of proteins associated with extracellular vesicles (EVs) isolated using an alternating current electrokinetic (ACE) system for the detection of early stage (I & II) non-small cell lung cancer (NS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c5a77f36c5135866708c739beacebd6
https://doi.org/10.1158/1538-7445.am2022-727
https://doi.org/10.1158/1538-7445.am2022-727
Autor:
Juan Pablo Hinestrosa Vélez
Publikováno v:
Revista Digital de Derecho Administrativo, Iss 4 (2010)
Teniendo en cuenta el fenómeno de la Constitucionalización del Derecho, en este caso del Derecho Administrativo y en especial la apertura y subordinación del ordenamiento jurídico colombiano al Derecho Internacional de los Derechos Humanos, se ha
Externí odkaz:
https://doaj.org/article/26201a24eb3a46e987a2b66e1c5b423f