SÍNTESIS SELECTIVA DEL PRECURSOR DE COMPUESTOS BIOACTIVOS 4-METIL-2-QUINOLONA EMPLEANDO EL REACTIVO DE EATON

Autor: Gisela C. Muscia, Ayelen Luczywo, Juan P. Carnevale, Graciela Y. Buldain, Silvia E. Asís

Publikováno v: Avances en Ciencias e Ingeniería, Vol 10, Iss 4, Pp 37-42 (2019)

In this paper the use of Eaton´s reagent for the selective synthesis of 4-methyl-2-quinolone is described, avoiding the use of mineral acids and expensive metal catalysts such as those described in the literature. This reagent is easily available an

Externí odkaz: https://doaj.org/article/834aa614c03242468697801180f50617

Synthesis, anti-tuberculosis activity and QSAR study of 2,4-diarylquinolines and analogous polycyclic derivatives

Autor: Ayelen Luczywo, Graciela Buldain, Juan P. Carnevale, Gisela Celeste Muscia, Ailen Rodríguez Ó Toole, María Victoria Peláez, Silvia E. Asis, Juan José Casal

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Arabian Journal of Chemistry, Vol 12, Iss 7, Pp 932-945 (2019)

The multicomponent syntheses of 2,4-di-aryl-quinolines and analogous polycyclic derivatives as anti-tuberculosis agents were described. They were prepared via Beyer and Friedländer methods under microwave irradiation in short reaction times and good

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec077729c2f12c0cc2d4a38319c8f0d
https://www.sciencedirect.com/science/article/pii/S1878535218302053

Microwave-assisted Friedländer synthesis of quinolines derivatives as potential antiparasitic agents

Autor: Juan P. Carnevale, Ana M. Bruno, Mariela Bollini, Gisela Celeste Muscia, Silvia E. Asis

Publikováno v: Tetrahedron Letters. 47:8811-8815

A series of substituted quinolines was developed via the Friedlander reaction employing microwave irradiation (MW), in the presence of a catalytic amount of hydrochloric acid. The products were obtained in good yields in 1.5–12 min and were tested

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f19ab0eaffd19e01bd695b5834f32c9
https://doi.org/10.1016/j.tetlet.2006.10.073