Zobrazeno 1 - 10
of 404
pro vyhledávání: '"Juan P Rodrigo"'
Autor:
Natalia Fernández-Parejo, L. Francisco Lorenzo-Martín, Juana M. García-Pedrero, Juan P. Rodrigo, Mercedes Dosil, Xosé R. Bustelo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract VAV2 is an activator of RHO GTPases that promotes and maintains regenerative proliferation-like states in normal keratinocytes and oral squamous cell carcinoma (OSCC) cells. Here, we demonstrate that VAV2 also regulates ribosome biogenesis i
Externí odkaz:
https://doaj.org/article/cc4d6834c3764ff9ae00a5011ff571bb
Autor:
Juan P. Rodrigo, Mario Sánchez-Canteli, María Otero-Rosales, Pablo Martínez-Camblor, Francisco Hermida-Prado, Juana M. García-Pedrero
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract Background Tumor mutational burden (TMB) has been demonstrated to predict the response to immune checkpoint inhibitors (ICIs) in various cancers. However, the role of TMB in head and neck squamous cell carcinoma (HNSCC) has not yet been spec
Externí odkaz:
https://doaj.org/article/4e57d01ea0994bee808b0294c5862597
Autor:
Alvaro Llorente, Javier Guinea Perez, Juan Antonio Rodrigo, David Jimenez, Jose Manuel Menendez
Publikováno v:
IEEE Access, Vol 12, Pp 34846-34862 (2024)
No-Reference video quality assessment has become a trending and challenging hot topic in estimating perceived quality in audiovisual content. In this paper, we present a proposal to considerably reduce the computational cost of video processing witho
Externí odkaz:
https://doaj.org/article/ad731d5759614049a8e004d4082d8927
Autor:
Christian Sordo-Bahamonde, Seila Lorenzo-Herrero, Rocío Granda-Díaz, Alejandra Martínez-Pérez, Candelaria Aguilar-García, Juan P. Rodrigo, Juana M. García-Pedrero, Segundo Gonzalez
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-15 (2023)
Abstract Recent introduction of monoclonal antibodies targeting immune checkpoints to harness antitumor immunity has revolutionized the cancer treatment landscape. The therapeutic success of immune checkpoint blockade (ICB)-based therapies mainly rel
Externí odkaz:
https://doaj.org/article/b573d64d699d4fee9f588ef47f02be6d
Autor:
Lucia Morgado-Palacin, Jessie A. Brown, Thomas F. Martinez, Juana M. Garcia-Pedrero, Farhad Forouhar, S. Aidan Quinn, Clara Reglero, Joan Vaughan, Yasamin Hajy Heydary, Cynthia Donaldson, Sandra Rodriguez-Perales, Eva Allonca, Rocio Granda-Diaz, Agustin F. Fernandez, Mario F. Fraga, Arianna L. Kim, Jorge Santos-Juanes, David M. Owens, Juan P. Rodrigo, Alan Saghatelian, Adolfo A. Ferrando
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
TINCR encodes a p53-regulated ubiquitin-like microprotein expressed in stratified epithelia. Tincr loss promotes UVB-induced skin carcinogenesis in mice and deletions and mutations in human squamous cell carcinoma support a tumor suppressor role.
Externí odkaz:
https://doaj.org/article/99397db4eb4344f19ba418b654b42f08
Autor:
César Álvarez-Marcos, Andrea Vicente-Benito, Águeda Gayol-Fernández, Daniel Pedregal-Mallo, Paloma Sirgo-Rodríguez, Liliana Santamarina-Rabanal, José Luis Llorente, Fernando López, Juan Pablo Rodrigo
Publikováno v:
Acta Otorhinolaryngologica Italica, Vol 42, Iss 3, Pp 243-249 (2022)
Externí odkaz:
https://doaj.org/article/2e2a29130aa14c76873b16021efd771f
Prognostic Significance of β-Catenin in Relation to the Tumor Immune Microenvironment in Oral Cancer
Autor:
Paloma Lequerica-Fernández, Tania Rodríguez-Santamarta, Eduardo García-García, Verónica Blanco-Lorenzo, Héctor E. Torres-Rivas, Juan P. Rodrigo, Faustino J. Suárez-Sánchez, Juana M. García-Pedrero, Juan Carlos De Vicente
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2675 (2023)
The aim of this study was to investigate the prognostic relevance of β-catenin expression in oral squamous cell carcinoma (OSCC) and to explore relationships with the tumor immune microenvironment. Expression of β-catenin and PD-L1, as well as lymp
Externí odkaz:
https://doaj.org/article/c249002560264b7db54ccd1d9cf25fed
Autor:
Karthik Nagaraja Rao, Prathamesh S. Pai, Prajwal Dange, Luiz P. Kowalski, Primož Strojan, Antti A. Mäkitie, Orlando Guntinas-Lichius, K. Thomas Robbins, Juan P. Rodrigo, Avraham Eisbruch, Robert P. Takes, Remco de Bree, Andrés Coca-Pelaz, Cesare Piazza, Carlos Chiesa-Estomba, Fernando López, Nabil F. Saba, Alessandra Rinaldo, Alfio Ferlito
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2128 (2023)
Background: The management of cT3 laryngeal cancers remains controversial, with studies recommending surgical or non-surgical approaches. Despite the many papers that have been published on the subject, there is a lack of studies showing which treatm
Externí odkaz:
https://doaj.org/article/b412560501ed4e49a86168bce1be36cf
Autor:
María Cielo Pasten, José Carballo, Jimena Gallardo, Diego Zappacosta, Juan Pablo Selva, Juan Manuel Rodrigo, Viviana Echenique, Ingrid Garbus
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Weeping lovegrass (Eragrostis curvula [Shrad.] Nees) is a perennial grass typically established in semi-arid regions, with good adaptability to dry conditions and sandy soils. This polymorphic complex includes both sexual and apomictic cytotypes, wit
Externí odkaz:
https://doaj.org/article/8a78710499d049b88faa8ad2a774d538
Autor:
Blanca Ramírez Barat, Emilio Cano, María Teresa Molina, Miguel Antonio Barbero-Álvarez, Juan Antonio Rodrigo, José Manuel Menéndez
Publikováno v:
Heritage Science, Vol 9, Iss 1, Pp 1-9 (2021)
Abstract Colour changes of cultural heritage objects can be related with degradation of materials, thus a proper colour monitoring system can be used to detect conservation problems. With this purpose, a monitoring methodology for cultural heritage p
Externí odkaz:
https://doaj.org/article/b4e5918b9f9544ae9f2ff23d071375c1