Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Juan Mucci"'
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24595- (2024)
Nearly all expression vectors currently available for Trypanosoma cruzi were conceived to produce a single primary transcript containing the genes of interest along with those that confer antibiotic resistance. However, since each messenger RNA (mRNA
Externí odkaz:
https://doaj.org/article/2b472b1b24be44bda04f14e4fb9146fd
Autor:
Martín Somoza, Adriano Bertelli, Cecilia A. Pratto, Ramiro E. Verdun, Oscar Campetella, Juan Mucci
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
Trypanosoma cruzi infection induces a polyclonal B cell proliferative response characterized by maturation to plasma cells, excessive generation of germinal centers, and secretion of parasite-unrelated antibodies. Although traditionally reduced to th
Externí odkaz:
https://doaj.org/article/e393a2339de8468db7bc05188ff2e188
Autor:
Jimena Borgo, Orlando G. Elso, Jessica Gomez, Mauro Coll, Cesar A. N. Catalán, Juan Mucci, Guzmán Alvarez, Lía M. Randall, Patricia Barrera, Emilio L. Malchiodi, Augusto E. Bivona, María Florencia Martini, Valeria P. Sülsen
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 647 (2023)
Stevia species (Asteraceae) have been a rich source of terpenoid compounds, mainly sesquiterpene lactones, several of which show antiprotozoal activity. In the search for new trypanocidal compounds, S. satureiifolia var. satureiifolia and S. alpina w
Externí odkaz:
https://doaj.org/article/7f501a003c8248bcb73415679501227a
Autor:
Cristian Gabriel Beccaria, María Carolina Amezcua Vesely, Facundo Fiocca Vernengo, Ricardo Carlos Gehrau, María Cecilia Ramello, Jimena Tosello Boari, Melisa Gorosito Serrán, Juan Mucci, Eliane Piaggio, Oscar Campetella, Eva Virginia Acosta Rodríguez, Carolina Lucía Montes, Adriana Gruppi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Germinal center (GC) is where B cells interact with other immune cells for optimal induction of antibody responses. Here the authors show that galectin-3 regulates GC development by modulating interferon-γ and B cell-intrinsic signaling, such that g
Externí odkaz:
https://doaj.org/article/e56f9c7562ff48e1b8ef2534da1247d2
Autor:
Maite Lobo, Virginia Balouz, Luciano Melli, Giannina Carlevaro, María E Cortina, María de Los Milagros Cámara, Gaspar E Cánepa, Santiago J Carmona, Jaime Altcheh, Oscar Campetella, Andrés E Ciocchini, Fernán Agüero, Juan Mucci, Carlos A Buscaglia
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 3, p e0007245 (2019)
BACKGROUND:TolT was originally described as a Trypanosoma cruzi molecule that accumulated on the trypomastigote flagellum bearing similarity to bacterial TolA colicins receptors. Preliminary biochemical studies indicated that TolT resolved in SDS-PAG
Externí odkaz:
https://doaj.org/article/084386b17edb44459ea0f1c8f4f44583
Autor:
Juan Mucci, Santiago J Carmona, Romina Volcovich, Jaime Altcheh, Estefanía Bracamonte, Jorge D Marco, Morten Nielsen, Carlos A Buscaglia, Fernán Agüero
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 10, p e0005972 (2017)
Chagas Disease, caused by the protozoan Trypanosoma cruzi, is a major health and economic problem in Latin America for which no vaccine or appropriate drugs for large-scale public health interventions are yet available. Accurate diagnosis is essentia
Externí odkaz:
https://doaj.org/article/05db6acf4bbe4db5976c14a785c4ac5a
Autor:
María de Los Milagros Cámara, Gaspar E Cánepa, Andrés B Lantos, Virginia Balouz, Hai Yu, Xi Chen, Oscar Campetella, Juan Mucci, Carlos A Buscaglia
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 8, p e0005856 (2017)
TSSA (Trypomastigote Small Surface Antigen) is an antigenic, adhesion molecule displayed on the surface of Trypanosoma cruzi trypomastigotes. TSSA displays substantial sequence identity to members of the TcMUC gene family, which code for the trypomas
Externí odkaz:
https://doaj.org/article/f0c0c58d5bb349fdbcd0ce3e51f34bfd
Autor:
Andrés B Lantos, Giannina Carlevaro, Beatriz Araoz, Pablo Ruiz Diaz, María de Los Milagros Camara, Carlos A Buscaglia, Mariano Bossi, Hai Yu, Xi Chen, Carolyn R Bertozzi, Juan Mucci, Oscar Campetella
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005559 (2016)
Trypanosoma cruzi, the flagellate protozoan agent of Chagas disease or American trypanosomiasis, is unable to synthesize sialic acids de novo. Mucins and trans-sialidase (TS) are substrate and enzyme, respectively, of the glycobiological system that
Externí odkaz:
https://doaj.org/article/2938052e3d294e9d8a82d59c4f7acdd1
Publikováno v:
PLoS Pathogens, Vol 10, Iss 6, p e1004224 (2014)
Trypanosoma cruzi is the etiologic agent of Chagas disease. Although this is not a free-living organism it has conserved a contractile vacuole complex (CVC) to regulate its osmolarity. This obligate intracellular pathogen is, in addition, dependent o
Externí odkaz:
https://doaj.org/article/ff9b5db9e83448df8b0ba9f08a5a689d
Autor:
Roberto Juan Mucci
En la Conferencia Mundial sobre'El papel de la Universidad en la lucha por la paz', realizada en Viena, Austria entre el 25 y 29 de agosto de 1969, Viktor Frankl pronuncia un discurso donde utiliza la palabra Monantropismo, y nos dice:'La mera superv
