Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Juan Miguel Diaz-Tocados"'
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Akademický článek
Procaine Inhibits Osteo/Odontogenesis through Wnt/β-Catenin Inactivation.
Autor: Carmen Herencia, Juan Miguel Diaz-Tocados, Lidia Jurado, Addy Montes de Oca, Maria Encarnación Rodríguez-Ortiz, Carmen Martín-Alonso, Julio M Martínez-Moreno, Noemi Vergara, Mariano Rodríguez, Yolanda Almadén, Juan R Muñoz-Castañeda
Publikováno v: PLoS ONE, Vol 11, Iss 6, p e0156788 (2016)
Periodontitis is a complex pathology characterized by the loss of alveolar bone. The causes and the mechanisms that promote this bone resorption still remain unknown. The knowledge of the critical regulators involved in the alteration of alveolar bon
Externí odkaz: https://doaj.org/article/c62474a98a3d43048781fef9c528f37d
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2
Akademický článek
Multiple endocrine defects in adult-onset Sprouty1/2/4 triple knockout mice
Autor: Gisela Altés, Anna Olomí, Aida Perramon-Güell, Sara Hernández, Anna Casanovas, Aurora Pérez, Juan Miguel Díaz-Tocados, José Manuel Valdivielso, Cristina Megino, Raúl Navaridas, Xavier Matias-Guiu, Ophir D. Klein, Joaquim Egea, Xavi Dolcet, Andrée Yeramian, Mario Encinas
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Genes of the Sprouty family (Spry1-4) are feedback inhibitors of receptor tyrosine kinases, especially of Ret and the FGF receptors. As such, they play distinct and overlapping roles in embryo morphogenesis and are considered to be tumor sup
Externí odkaz: https://doaj.org/article/c35f82b053404988a6db6232e37d7598
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3
FC022: IPI3K/AKT/MTOR Pathway Regulates Renal Expression of Klotho
Autor: Aurora Pérez-Gomez, Juan Miguel Diaz-Tocados, Juan Diego Dominguez Coral, Maria Crespo-Masip, Alicia García-Carrasco, Nuria Doladé, Ana Martinez Bardaji, Jose M. Valdivielso
Publikováno v: Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Chronic kidney disease (CKD) represents an important and growing burden on health worldwide, mainly driven by the increase in the incidence of associated risk factors like diabetes. As kidney function declines, changes in mineral
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2bf3fbd6248e2eac369d07fa6fd5a6a9
https://doi.org/10.1093/ndt/gfac099.001
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4
MO551: Targeted Ablation of PTEN in Osteocytes Induces Severe Anemia and Increases FGF23 Production in Renal Insufficiency
Autor: Juan Miguel Diaz-Tocados, Aurora Pérez-Gomez, Juan Diego Dominguez Coral, Miguel Ángel Rodríguez Martín, Alicia García-Carrasco, Ana Martinez Bardaji, Auria Eritja Sanjuan, Maite Caus Enriquez, Milica Bozic, Jose M. Valdivielso
Publikováno v: Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Renal disease patients present bone alterations due to an imbalance of mineral metabolism. Previous studies have demonstrated that mice with conditional ablation of the phosphatase and tensin homolog (PTEN) in osteoblasts show inc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::545e1688fa51f5b439e3db2b3475df38
https://doi.org/10.1093/ndt/gfac073.015
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5
Elimination of Vitamin D Signaling Causes Increased Mortality in a Model of Overactivation of the Insulin Receptor: Role of Lipid Metabolism
Autor: Maria Crespo-Masip, Aurora Perez-Gomez, Alicia Garcia-Carrasco, Ramiro Jover, Carla Guzmán, Xavier Dolcet, Mercé Ibarz, Cristina Martínez, Àuria Eritja, Juan Miguel Diaz-Tocados, José Manuel Valdivielso
Publikováno v: Nutrients; Volume 14; Issue 7; Pages: 1516
Crespo Masip, María Pérez Gómez, Aurora García Carrasco, Alicia Jover Atienza, Ramiro Guzmán, Carla Dolcet, Xavier Ibarz, Mercé Martínez, Cristina Eritja, Àuria Diaz Tocados, Juan Miguel Valdivielso, Jose Manuel 2022 Elimination of Vitamin D Signaling Causes Increased Mortality in a Model of Overactivation of the Insulin Receptor: Role of Lipid Metabolism Nutrients 14 7 1 16
Nutrients
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Vitamin D (VD) deficiency has been associated with cancer and diabetes. Insulin signaling through the insulin receptor (IR) stimulates cellular responses by activating the PI3K/AKT pathway. PTEN is a tumor suppressor and a negative regulator of the p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eefc4ad77b12e03758a0c341fda0b27d
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6
The Increase in FGF23 Induced by Calcium Is Partially Dependent on Vitamin D Signaling
Autor: Sandra Rayego-Mateos, Nuria Doladé, Alicia García-Carrasco, Juan Miguel Diaz-Tocados, Merce Ibarz, Jose Manuel Valdivielso
Publikováno v: Nutrients; Volume 14; Issue 13; Pages: 2576
Background: Increased FGF23 levels are an early pathological feature in chronic kidney disease (CKD), causing increased cardiovascular risk. The regulation of FGF23 expression is complex and not completely understood. Thus, Ca2+ has been shown to ind
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a181b661988f200d1ed3e238e4f17051
https://doi.org/10.3390/nu14132576
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9
Akademický článek
The Role of Disturbed Mg Homeostasis in Chronic Kidney Disease Comorbidities
Autor: Cristian Rodelo-Haad, M. Victoria Pendón-Ruiz de Mier, Juan Miguel Díaz-Tocados, Alejandro Martin-Malo, Rafael Santamaria, Juan Rafael Muñoz-Castañeda, Mariano Rodríguez
Publikováno v: Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Some of the critical mechanisms that mediate chronic kidney disease (CKD) progression are associated with vascular calcifications, disbalance of mineral metabolism, increased oxidative and metabolic stress, inflammation, coagulation abnormalities, en
Externí odkaz: https://doaj.org/article/33951b3d37a64f4c83575a5a2e4db898
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10
Akademický článek
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