Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Juan María Blanco-Madrigal"'
Mucosal Immune Defence Gene Polymorphisms as Relevant Players in the Pathogenesis of IgA Vasculitis?
Autor:
Joao Carlos Batista-Liz, Vanesa Calvo-Río, María Sebastián Mora-Gil, Belén Sevilla-Pérez, Ana Márquez, María Teresa Leonardo, Ana Peñalba, Francisco David Carmona, Javier Narvaez, Luis Martín-Penagos, Lara Belmar-Vega, Cristina Gómez-Fernández, Luis Caminal-Montero, Paz Collado, Patricia Quiroga-Colina, Miren Uriarte-Ecenarro, Esteban Rubio, Manuel León Luque, Juan María Blanco-Madrigal, Eva Galíndez-Agirregoikoa, Javier Martín, Santos Castañeda, Miguel Angel González-Gay, Ricardo Blanco, Verónica Pulito-Cueto, Raquel López-Mejías
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13063 (2023)
ITGAM–ITGAX (rs11150612, rs11574637), VAV3 rs17019602, CARD9 rs4077515, DEFA (rs2738048, rs10086568), and HORMAD2 rs2412971 are mucosal immune defence polymorphisms, that have an impact on IgA production, described as risk loci for IgA nephropathy
Externí odkaz:
https://doaj.org/article/23769490ef1a46e7b80c99f9bac43115
Autor:
Diana Prieto-Peña, Sara Remuzgo-Martínez, Fernanda Genre, Verónica Pulito-Cueto, Belén Atienza-Mateo, Javier Llorca, Belén Sevilla-Pérez, Norberto Ortego-Centeno, Ana Marquez, Leticia Lera-Gómez, María Teresa Leonardo, Ana Peñalba, Javier Narváez, Luis Martín-Penagos, Emilio Rodrigo, José A. Miranda-Filloy, Luis Caminal-Montero, Paz Collado, Javier Sánchez Pérez, Diego de Argila, Esteban Rubio, Manuel León Luque, Juan María Blanco-Madrigal, Eva Galíndez-Agirregoikoa, Oreste Gualillo, Javier Martín, Santos Castañeda, Ricardo Blanco, Miguel A. González-Gay, Raquel López-Mejías
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Cytokines signalling pathway genes are crucial factors of the genetic network underlying the pathogenesis of Immunoglobulin-A vasculitis (IgAV), an inflammatory vascular condition. An influence of the interleukin (IL)33- IL1 receptor like (I
Externí odkaz:
https://doaj.org/article/4e5c12cf144c4687a3cac75fff04094d
Autor:
Diana Prieto-Peña, Fernanda Genre, Sara Remuzgo-Martínez, Verónica Pulito-Cueto, Belén Atienza-Mateo, Javier Llorca, Belén Sevilla-Pérez, Norberto Ortego-Centeno, Leticia Lera-Gómez, María Teresa Leonardo, Ana Peñalba, Javier Narváez, Luis Martín-Penagos, Emilio Rodrigo, José A. Miranda-Filloy, Luis Caminal-Montero, Paz Collado, Javier Sánchez Pérez, Diego de Argila, Esteban Rubio, Manuel León Luque, Juan María Blanco-Madrigal, Eva Galíndez-Agirregoikoa, Oreste Gualillo, Javier Martín, Santos Castañeda, Ricardo Blanco, Miguel A. González-Gay, Raquel López-Mejías
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract BAFF, APRIL and BAFF-R are key proteins involved in the development of B-lymphocytes and autoimmunity. Additionally, BAFF, APRIL and BAFFR polymorphisms were associated with immune-mediated conditions, being BAFF GCTGT>A a shared insertion-d
Externí odkaz:
https://doaj.org/article/cca02dff696e45aaac327228db5c45bf
Autor:
Joao Carlos Batista Liz, Fernanda Genre, Verónica Pulito-Cueto, Sara Remuzgo-Martínez, Diana Prieto-Peña, Ana Márquez, Norberto Ortego-Centeno, María Teresa Leonardo, Ana Peñalba, Javier Narváez, Luis Martín-Penagos, Lara Belmar-Vega, Cristina Gómez-Fernández, José A. Miranda-Filloy, Luis Caminal-Montero, Paz Collado, Diego De Árgila, Patricia Quiroga-Colina, Esther F. Vicente-Rabaneda, Ana Triguero-Martínez, Esteban Rubio, Manuel León Luque, Juan María Blanco-Madrigal, Eva Galíndez-Agirregoikoa, Javier Martín, Oreste Gualillo, Ricardo Blanco, Santos Castañeda, Miguel A. González-Gay, Raquel López-Mejías
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 19, p 5577 (2022)
CD40, BLK and BANK1 genes involved in the development and signaling of B-cells are identified as susceptibility loci for numerous inflammatory diseases. Accordingly, we assessed the potential influence of CD40, BLK and BANK1 on the pathogenesis of im
Externí odkaz:
https://doaj.org/article/e3d178ed56204c7e8813fcee49edaf96
Autor:
Diana Prieto-Peña, Fernanda Genre, Sara Remuzgo-Martínez, Verónica Pulito-Cueto, Belén Atienza-Mateo, Javier Llorca, Belén Sevilla-Pérez, Norberto Ortego-Centeno, Leticia Lera-Gómez, María Teresa Leonardo, Ana Peñalba, Javier Narváez, Luis Martín-Penagos, Emilio Rodrigo, José A. Miranda-Filloy, Luis Caminal-Montero, Paz Collado, Javier Sánchez Pérez, Diego de Argila, Esteban Rubio, Manuel León Luque, Juan María Blanco-Madrigal, Eva Galíndez-Agirregoikoa, Oreste Gualillo, Javier Martín, Santos Castañeda, Ricardo Blanco, Miguel A. González-Gay, Raquel López-Mejías
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/90dad8174dea42aabb16bad57e7b4770
Autor:
Raquel López-Mejías, F. David Carmona, Santos Castañeda, Fernanda Genre, Sara Remuzgo-Martínez, Belén Sevilla-Perez, Norberto Ortego-Centeno, Javier Llorca, Begoña Ubilla, Verónica Mijares, Trinitario Pina, José A. Miranda-Filloy, Antonio Navas Parejo, Diego de Argila, Maximiliano Aragües, Esteban Rubio, Manuel León Luque, Juan María Blanco-Madrigal, Eva Galíndez-Aguirregoikoa, David Jayne, Ricardo Blanco, Javier Martín, Miguel A. González-Gay
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-6 (2017)
Abstract The genetic component of Immunoglobulin-A (IgA) vasculitis is still far to be elucidated. To increase the current knowledge on the genetic component of this vasculitis we performed the first genome-wide association study (GWAS) on this condi
Externí odkaz:
https://doaj.org/article/3e33d0a736e14f4593fe38919470b3d3
Autor:
Manuel José Moreno-Ramos, Carlos Sanchez-Piedra, Olga Martínez-González, Carlos Rodríguez-Lozano, Carolina Pérez-Garcia, Mercedes Freire, Cristina Campos, Rafael Cáliz-Caliz, Jerusalem Calvo, Juan María Blanco-Madrigal, Ana Pérez-Gómez, María José Moreno-Martínez, Luis Linares, Fernando Sánchez-Alonso, Carlos Sastré, Isabel Castrejón
Rheumatic diseases are extensively managed with biological disease-modifying antirheumatic drugs (bDMARDs), but a notable proportion of patients withdraw in the long term because of lack of effectiveness, adverse events, or the patient's decision. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f481ad736f5d46ac94b282bc151f0f0
http://hdl.handle.net/10230/55082
http://hdl.handle.net/10230/55082