Developing a model to predict the early risk of hypertriglyceridemia based on inhibiting lipoprotein lipase (LPL): a translational study

Autor: Julia Hernandez-Baixauli, Gertruda Chomiciute, Juan María Alcaide-Hidalgo, Anna Crescenti, Laura Baselga-Escudero, Hector Palacios-Jordan, Elisabet Foguet-Romero, Anna Pedret, Rosa M. Valls, Rosa Solà, Miquel Mulero, Josep M. Del Bas

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)

Abstract Hypertriglyceridemia (HTG) is an independent risk factor for atherosclerotic cardiovascular disease (ASCVD). One of the multiple origins of HTG alteration is impaired lipoprotein lipase (LPL) activity, which is an emerging target for HTG tre

Externí odkaz: https://doaj.org/article/5977faa0b5514c9abf1d0b586b424485

A double-blinded, randomized, parallel intervention to evaluate biomarker-based nutrition plans for weight loss

Autor: Mona A. Aldubayan, Kristina Pigsborg, Sophia M.O. Gormsen, Francisca Serra, Mariona Palou, Sebastià Galmés, Andreu Palou-March, Claudia Favari, Mart Wetzels, Alberto Calleja, Miguel Angel Rodríguez Gómez, María Guirro Castellnou, Antoni Caimari, Mar Galofré, David Suñol, Xavier Escoté, Juan María Alcaide-Hidalgo, Josep M del Bas, Biotza Gutierrez, Thure Krarup, Mads F. Hjorth, Faidon Magkos

Publikováno v: Aldubayan, M A, Pigsborg, K, Gormsen, S M O, Serra, F, Palou, M, Galmés, S, Palou-March, A, Favari, C, Wetzels, M, Calleja, A, Rodríguez Gómez, M A, Castellnou, M G, Caimari, A, Galofré, M, Suñol, D, Escoté, X, Alcaide-Hidalgo, J M, M Del Bas, J, Gutierrez, B, Krarup, T, Hjorth, M F & Magkos, F 2022, ' A double-blinded, randomized, parallel intervention to evaluate biomarker-based nutrition plans for weight loss: The PREVENTOMICS study ', Clinical Nutrition, vol. 41, no. 8, pp. 1834-1844 . https://doi.org/10.1016/j.clnu.2022.06.032
Clinical Nutrition, 41(8), 1834-1844. Churchill Livingstone

Background & aims Growing evidence suggests that biomarker-guided dietary interventions can optimize response to treatment. In this study, we evaluated the efficacy of the PREVENTOMCIS platform—which uses metabolomic and genetic information to clas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5542c5cedd78169dfc3ec69d0356d2d
http://www.scopus.com/inward/record.url?scp=85134158333&partnerID=8YFLogxK

Identification of novel antihypertensive peptides from wine lees hydrolysate

Autor: Miquel Mulero, Raúl López-Fernández-Sobrino, Juan María Alcaide-Hidalgo, Francisca Isabel Bravo, Cristina Torres-Fuentes, Begoña Muguerza, Anna Mas-Capdevila

Publikováno v: Food chemistry. 366

Enzymatic-assisted extraction using Flavourzyme® has been demonstrated to be a useful methodology to obtain wine lees (WL) enriched in phenolic compounds and with enhanced antihypertensive activity. Nevertheless, taking into account that Flavourzyme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ba69f07b8cf1c7ba9c4de031dc3e6b
https://pubmed.ncbi.nlm.nih.gov/34343949

Antihypertensive Effects of Virgin Olive Oil (Unfiltered) Low Molecular Weight Peptides with ACE Inhibitory Activity in Spontaneously Hypertensive Rats

Autor: Juan Duarte, Juan María Alcaide-Hidalgo, Miguel Romero, Eduardo López-Huertas

Publikováno v: Nutrients
Volume 12
Issue 1
Nutrients, Vol 12, Iss 1, p 271 (2020)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Digital.CSIC. Repositorio Institucional del CSIC

The low molecular weight peptide composition of virgin olive oil (VOO) is mostly unknown. We hypothesised that unfiltered VOO could possess low molecular weight peptides with antihypertensive activity. We produced unfiltered VOO and obtained a water-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232362e783c299fc4aacf5e20c07dca2

Metabolomics Elucidates Dose-Dependent Molecular Beneficial Effects of Hesperidin Supplementation in Rats Fed an Obesogenic Diet

Autor: Maria Guirro, Andreu Gual-Grau, Albert Gibert-Ramos, Lluís Arola, Juan María Alcaide-Hidalgo, Núria Canela, Jordi Mayneris-Perxachs

Publikováno v: Antioxidants
Volume 9
Issue 1
Antioxidants, Vol 9, Iss 1, p 79 (2020)

Metabolic syndrome (MetS) is a global epidemic concern. Polyphenols are proposed as good candidates for its prevention, although their mechanisms are not fully understood. The gut microbiota seems to play a key role in polyphenol beneficial effects.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de00ee5feee6d26ad05c648909a4af85
http://europepmc.org/articles/PMC7023145