Failure on voxilaprevir, velpatasvir, sofosbuvir and efficacy of rescue therapy

Autor: Ada Bertoli, Michael P. Manns, M. Katja Deterding, Vanni Borghi, Silvia Barbaliscia, Elisabetta Degasperi, Julian Schulze zur Wiesch, Velia Chiara Di Maio, Ansgar W. Lohse, Wolfgang Schmidt, Markus Cornberg, Christophe Moreno, Tomas Beyer, Federico García, Johannes Vermehren, Pietro Lampertico, Andreas E. Kremer, Laura Sighinolfi, Felix Piecha, Magdalena Lara, Pier Luigi Toniutto, Christoph Sarrazin, Antonio Craxì, Francesca Ceccherini-Silberstein, Jonas Schreiber, Jesús Santos, Ana Belén Pérez, Alessio Aghemo, William Gennari, Lorenzo Magenta, Manuel Alberto Macias Rodriguez, Heiner Wedermeyer, Ana Fuentes, Stephan Grunwald, Jose Miguel Rosales Zabal, Francisco Téllez, Dolores Merino, Burkhard Jäger, Miguel García Deltoro, Juan Manuel Pascasio-Acevedo, Blanca Figueruela, Andreas Stallmach, Renate Heyne, Valeria Ghisetti, Christoph P. Berg, Carlo Federico Perno, Elisa Fernández-Fuertes, Nikolaus Kordecki, Ana María Martinez Sapiña, Natalia Chueca, Andreas Herrmann, Eva Jägel-Guedes, Vincenza Calvaruso, Maurizio Zazzi, Massimo Andreoni, Lucio Boglione, Mario Angelico, Simona Francioso, Giuseppe Cariti, Cristina Quilez, Tiziano Allice, Christiana Graf, Leopoldo Muñoz-Medina, Fausto Baldanti, Rudolf E. Stauber, Jürgen Siebler, Julia Dietz, Maria Josefa Rodriguez Pardo, Kerstin Port, Heinz Zoller, Juan Carlos Alados, Stefan Zeuzem, Juan Ignacio Arenas Ruiz-Tapiador, Joaquín Cabezas, Stefania Paolucci, Axels Baumgarten, Kai-Henrik Peiffer, Adolfo de Salazar, Pietro Pozzoni, Miguel Jimenez, Hjördis Möller

Publikováno v: Journal of Hepatology. 74:801-810

Background & Aims There are limited data on patients with chronic HCV infection in whom combination voxilaprevir (VOX), velpatasvir (VEL), sofosbuvir (SOF) retreatment fails. Thus, we aimed to assess treatment failure and rescue treatment options in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88cd0ab9dd512362a11eac31e987e6ab
https://doi.org/10.1016/j.jhep.2020.11.017

Hepatitis B surface antigen loss after discontinuing nucleos(t)ide analogue for treatment of chronic hepatitis B patients is persistent in White patients

Autor: Rosa Maria Morillas, Juan Arenas Ruiz Tapiador, Javier Crespo, Rafael Gómez-Rodríguez, Manuel Rodríguez, José Manuel Zozaya, Marta Casado, Juan Manuel Pascasio-Acevedo, Miguel Angel Simón, J. Fuentes, Martín Prieto, Blanca Figueruela, Jose Luis Calleja, Maria Buti, Moisés Diago, T. Casanovas, E. Suárez, Esther Molina

Publikováno v: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
r-FIHGUV. Repositorio Institucional de Producción Científica de la Fundación de Investigación del Hospital General de Valencia
instname
Digital.CSIC. Repositorio Institucional del CSIC
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe

OBJECTIVE: The objective of this study was to determine the long-term clinical outcome and persistence of hepatitis B surface antigen (HBsAg) loss after discontinuation of treatment. BACKGROUND: The prognosis of patients with chronic hepatitis B (CHB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd37d07e258cb2d84ab217bf638f51fb
https://doi.org/10.1097/meg.0000000000001289

Drug-induced liver injury due to mesterolone: A case report

Autor: Domingo, Pérez Palacios, Álvaro, Giráldez Gallego, Virginia, Carballo Rubio, Ana, Solà Fernández, Juan Manuel, Pascasio Acevedo

Publikováno v: Gastroenterología y Hepatología (English Edition). 42:629-630

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a72aa6cc8c9653e3e29d4205705f3c4
https://doi.org/10.1016/j.gastre.2019.06.004

Efficacy of Sofosbuvir and Velpatasvir, With and Without Ribavirin, in Patients With Hepatitis C Virus Genotype 3 Infection and Cirrhosis

Autor: Xavier Forns, Luis Enrique Morano Amado, Antonio Rivero, Juan A. Pineda, Rosa Maria Morillas, José A. Carrión, Luisa M. Stamm, Gregory Camus, Manuel J. Rodriguez, Sabela Lens, Raúl J. Andrade, Gulan Zhang, G. Mani Subramanian, Mar Riveiro-Barciela, Juan Turnes, Jose Luis Calleja, Rafael Esteban, Diana M. Brainard, Brian McNabb, Juan Manuel Pascasio Acevedo, Marta Casado, Maria Buti

Background & Aims In phase 3 trials and real-world settings, smaller proportions of patients with genotype 3 hepatitis C virus (HCV) infection and cirrhosis have a sustained virologic response 12 weeks after treatment (SVR12) with the combination of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55a62f588ce135fa70681f93b7ac76e
http://repositori.upf.edu/bitstream/10230/37186/1/esteban-gas-effi.pdf

High efficacy of Sofosbuvir plus Simeprevir in a large cohort of Spanish cirrhotic patients infected with genotypes 1 and 4

Autor: Álvaro Giráldez, Javier Crespo, Lluis Castells, Juan Manuel Pascasio-Acevedo, Carme Baliellas, Ana Arencibia, Valentín Cuervas-Mons, Xavier Forns, Alejandro Blasco, Joaquín Cabezas, Javier García-Samaniego, Juan Turnes, I. Narváez, V. Hontangas, Montserrat Forné, Adolfo Gallego, Zoe Mariño, Alexandra Gómez, Inmaculada Fernández, J.J. Sanchez-Ruano, Maria Ángeles Castro, Sonia Pascual, Carmen López-Núñez, Martín Prieto, Francisco Gea-Rodríguez, Jose Luis Calleja, José Castellote, José A. Carrión, Xavier Torras, Manuel Romero-Gómez, Moisés Diago, Tomas de Artaza, José Luis Montero, Rosa Maria Morillas, José María Moreno, Gloria Sánchez-Antolín, Mercedes Vergara

Publikováno v: RUC. Repositorio da Universidade da Coruña
instname
Liver International
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
LIVER INTERNATIONAL
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau

[Abstract] Background and Aims. Hepatitis C (HCV) therapy with Sofosbuvir (SOF)/Simeprevir (SMV) in clinical trials and real‐world clinical practice, showed high rates of sustained virological response (SVR) in non‐cirrhotic genotype (GT)‐1 and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd0695de76259d39ee41385f3213c5b
http://hdl.handle.net/2183/20993