Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Juan Manuel Murillo-Maldonado"'
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2, p 630 (2020)
Human mutations in the transcription and nucleotide excision repair (NER) factor TFIIH are linked with three human syndromes: xeroderma pigmentosum (XP), trichothiodystrophy (TTD) and Cockayne syndrome (CS). In particular, different mutations in the
Externí odkaz:
https://doaj.org/article/27947599decf419d97e7f45cdf4f028b
Autor:
Marco Rosales-Vega, Adriana Hernández-Becerril, Juan Manuel Murillo-Maldonado, Mario Zurita, Martha Vázquez
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0206587 (2018)
Regulation of developmental gene expression in eukaryotes involves several levels. One of them is the maintenance of gene expression along the life of the animal once it is started by different triggers early in development. One of the questions in t
Externí odkaz:
https://doaj.org/article/480c14eb108f44b284608ca28f4b1a34
Publikováno v:
General and comparative endocrinology. 330
Since practically a century ago, the insulin pathway was discovered in both vertebrates and invertebrates, implying an evolutionarily ancient origin. After a century of research, it is now clear that the insulin signal transduction pathway is a criti
Publikováno v:
BioMed Research International, Vol 2019 (2019)
BioMed Research International
BioMed Research International
The insulin pathway is an anabolic pathway that controls, amongst other things, glucose homeostasis. It is an evolutionarily conserved pathway. Disruptions in insulin pathway functions can lead to diabetic states. Diabetes, a very common occurrence i
Autor:
Viviana Valadez-Graham, Juan Manuel Murillo-Maldonado, Ana Karina Cruz, Rosario Rodriguez-Arnaiz, Vanessa Bahena, América Nitxin Castañeda-Sortibrán, Mario Zurita, Joselyn Chávez
Publikováno v:
Chromosoma. 126:697-712
Telomeres are important contributors to genome stability, as they prevent linear chromosome end degradation and contribute to the avoidance of telomeric fusions. An important component of the telomeres is the heterochromatin protein 1a (HP1a). Mutati
Publikováno v:
Developmental dynamics : an official publication of the American Association of AnatomistsREFERENCES. 248(11)
lncRNAs, genes transcribed but not translated, longer than 200 nucleotides, are classified as a separate class of nonprotein coding genes. Since their discovery, largely from RNAseq data, a number of pioneer studies have begun to unravel its myriad f
Autor:
Marta Clemente-Ruiz, Lidia Pérez, Juan Manuel Murillo-Maldonado, Lara Barrio, Gonzalo Quiroga, Najate Benhra, Marco Milán, Angel R. Nebreda
Publikováno v:
Developmental Cell. 36(3):290-302
SummaryChromosomal instability (CIN) is thought to be a source of mutability in cancer. However, CIN often results in aneuploidy, which compromises cell fitness. Here, we used the dosage compensation mechanism (DCM) of Drosophila to demonstrate that
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 2, p 630 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 2, p 630 (2020)
Human mutations in the transcription and nucleotide excision repair (NER) factor TFIIH are linked with three human syndromes: xeroderma pigmentosum (XP), trichothiodystrophy (TTD) and Cockayne syndrome (CS). In particular, different mutations in the
Publikováno v:
PeerJ, Vol 6, p e5042 (2018)
PeerJ
PeerJ
Morphogenetic movements during embryogenesis require dynamic changes in epithelial cell polarity and cytoskeletal reorganization. Such changes involve, among others, rearrangements of cell-cell contacts and protein traffic. InDrosophila melanogaster,
Publikováno v:
Mechanisms of development. 144
We review the use of a model organism to study the effects of a slow course, degenerative disease: namely, diabetes mellitus. Development and aging are biological phenomena entailing reproduction, growth, and differentiation, and then decline and pro