Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Juan Manuel Leyva Castillo"'
Autor:
Juan-Manuel Leyva-Castillo, Mrinmoy Das, Jennifer Kane, Maria Strakosha, Sonal Singh, Daniel Sen Hoi Wong, Alexander R. Horswill, Hajime Karasuyama, Frank Brombacher, Lloyd S. Miller, Raif S. Geha
Publikováno v:
JCI Insight, Vol 6, Iss 21 (2021)
Superficial cutaneous Staphylococcus aureus (S. aureus) infection in humans can lead to soft tissue infection, an important cause of morbidity and mortality. IL-17A production by skin TCRγδ+ cells in response to IL-1 and IL-23 produced by epithelia
Externí odkaz:
https://doaj.org/article/f92c5bebf6394434bab77102e9cc1d06
Publikováno v:
JID Innovations, Vol 1, Iss 3, Pp 100059- (2021)
In a new article published in JID Innovations, Nakatani-Kusakabe et al. (2021) show that type 2 innate lymphoid cells (ILC2s) in the skin of mice with IL-33 overexpression in keratinocytes are heterogeneous and consist of two distinct populations: sk
Externí odkaz:
https://doaj.org/article/17f669241eb54d7a9d91ccbb8a612b3e
Autor:
Barbara Yang, Hazel Wilkie, Mrinmoy Das, Maheshwor Timilshina, Wayne Bainter, Brian Woods, Michelle Daya, Meher P. Boorgula, Rasika A. Mathias, Peggy Lai, Carter R. Petty, Edie Weller, Hani Harb, Talal A. Chatila, Donald Y.M. Leung, Lisa A. Beck, Eric L. Simpson, Tissa R. Hata, Kathleen C. Barnes, Wanda Phipatanakul, Juan-Manuel Leyva-Castillo, Raif S. Geha
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:1296-1306.e7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::249907ebb664b8a107046b6890132b67
https://doi.org/10.1016/j.jaci.2023.01.011
https://doi.org/10.1016/j.jaci.2023.01.011
Autor:
Sonal Singh, Frank Brombacher, Lloyd S. Miller, Alexander R. Horswill, Raif S. Geha, Jennifer Kane, Hajime Karasuyama, Daniel Sen Hoi Wong, Mrinmoy Das, Maria Strakosha, Juan Manuel Leyva-Castillo
Publikováno v:
JCI Insight
Superficial cutaneous Staphylococcus aureus (S. aureus) infection in humans can lead to soft tissue infection, an important cause of morbidity and mortality. IL-17A production by skin TCRγδ+ cells in response to IL-1 and IL-23 produced by epithelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6362f6a233a672f5da6a7aab19de0dad
https://doi.org/10.1172/jci.insight.149953
https://doi.org/10.1172/jci.insight.149953
Autor:
Juan Manuel Leyva-Castillo, Liang Sun, Shih-Ying Wu, Shira Rockowitz, Piotr Sliz, Raif S. Geha
Publikováno v:
The Journal of allergy and clinical immunology. 150(2)
Allergic skin inflammation elicited in mice by epicutaneous (EC) sensitization with antigen shares characteristics with human atopic dermatitis (AD).We characterized gene expression by single cells in mouse skin undergoing antigen-driven allergic inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a95c82001895f8660e0f721a9f45140
https://pubmed.ncbi.nlm.nih.gov/35300986
https://pubmed.ncbi.nlm.nih.gov/35300986
Publikováno v:
Journal of Allergy and Clinical Immunology. 148:708-709
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cc7200f0b318836b7e48d1dfd76ad8b
https://doi.org/10.1016/j.jaci.2021.06.010
https://doi.org/10.1016/j.jaci.2021.06.010
Autor:
Juan Manuel Leyva-Castillo, Daniel Wong, Thomas Bieber, Haifa H. Jabara, Joerg Wenzel, Raif S. Geha, Alex McGurk
Publikováno v:
Clin Immunol
Atopic dermatitis (AD) is the most common inflammatory skin disease. It is characterized by a defective skin barrier and a Th2 dominated skin inflammation. The TNF family member a proliferation-inducing ligand (APRIL) and its receptors transmembrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bdfbc572f909065aca24b34f7d65dcb
https://pubmed.ncbi.nlm.nih.gov/32777271
https://pubmed.ncbi.nlm.nih.gov/32777271
Autor:
Juan Manuel, Leyva-Castillo, Mrinmoy, Das, Emilie, Artru, Juhan, Yoon, Claire, Galand, Raif S, Geha
Publikováno v:
The Journal of allergy and clinical immunology. 147(6)
Atopic dermatitis (AD) is characterized by a skin barrier defect aggravated by mechanical injury inflicted by scratching, a TOur aim was to determine the role of IL-13 in initiation of the TWild-type, Il13Tape stripping caused IL-33-driven upregulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::896b558897ce5e6253970d6bb13de90f
https://pubmed.ncbi.nlm.nih.gov/33831419
https://pubmed.ncbi.nlm.nih.gov/33831419
DOCK8 Expression in Regulatory T Cells Maintains their Stability and Limits Contact Hypersensitivity
Publikováno v:
J Invest Dermatol
Chronic dermatitis is a hallmark of Dedicator of cytokinesis 8 (DOCK8) deficiency. The migration of DOCK8-deficient T cells to the skin and their survival there have been reported to be defective. Surprisingly, we found that Dock8−/− mice demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f29f42c3e2235caabcb2ea194bbde3
https://pubmed.ncbi.nlm.nih.gov/33171169
https://pubmed.ncbi.nlm.nih.gov/33171169
Autor:
Amir Massoud, Juan Manuel Leyva-Castillo, Amirhosein J. Mousavi, Louis-Marie Charbonnier, Sena Arbag, Boris Guennewig, Klaus Schmitz-Abe, Amparito Cunnigham, Mehdi Benamar, Wanda Phipatanakul, Raif S. Geha, Hani Harb, Ye Cui, Elena Crestani, Talal A. Chatila, Constantinos Sioutas, Safa Baris, Emmanuel Stephen-Victor
Publikováno v:
Nature immunology
Elucidating the mechanisms that sustain asthmatic inflammation is critical for precision therapies. We found that interleukin-6- and STAT3 transcription factor-dependent upregulation of Notch4 receptor on lung tissue regulatory T (T-reg) cells is nec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fde3b563f859a57727acd256aba7342
https://pubmed.ncbi.nlm.nih.gov/34050948
https://pubmed.ncbi.nlm.nih.gov/34050948