Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Juan Manuel Cardenas-Maestre"'
Publikováno v:
Macromolecular Bioscience. 14:923-928
A novel multifunctional probe to monitor intracellular enzymatic activity in living cells is successfully developed. Their use as accurate intracellular sensors by conjugation of an internal control (that gives an extra feature to both evaluate cellu
Autor:
Geraldine Escher, Juan Manuel Cardenas-Maestre, Lois M. Alexander, Neil Q. McDonald, Rosario M. Sánchez-Martín, Kevin Dhaliwal, Asier Unciti-Broceta, Mark Bradley, Christopher Haslett, Maurits A. Jansen, John Simpson
Publikováno v:
Faraday Discuss.. 149:107-114
The need to understand cellular trafficking in vivo in situ requires the development and application of novel methodologies for cellular labeling and cell tracking. Here we applied new technologies associated with advances in molecular imaging to dem
Autor:
Anestis Tsakiridis, Rosario M. Sánchez-Martín, Joshua M. Brickman, Lois M. Alexander, Juan Manuel Cardenas-Maestre, Mathilde Muzerelle, Mark Bradley
Publikováno v:
ChemBioChem. 10:1453-1456
Delivering the goods: By coupling proteins to varyingly sized polymeric microspheres, it is possible to deliver them to cells in an easy and effective way. For this study a fluorescent protein (EGFP) and a functional enzyme (β-galactosidase) were co
Publikováno v:
Bioconjugate chemistry. 22(10)
A new approach for microsphere-mediated delivery of plasmid DNA has been developed and successfully evaluated. Basic molecular biology techniques were used to linearize and functionalize plasmid DNA by aminomodification, enabling efficient conjugatio
Publikováno v:
Ideas in Chemistry and Molecular Sciences: Where Chemistry Meets Life
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcff824176183f873977b2e4558fb468
https://doi.org/10.1002/9783527630516.ch5
https://doi.org/10.1002/9783527630516.ch5
Autor:
José A. Gómez-Vidal, Ana M. Pérez-López, Rosario M. Sánchez-Martín, José F. Domínguez-Seglar, Sonia Panadero-Fajardo, Juan Manuel Cardenas-Maestre
Publikováno v:
Drug Discovery Today. 15:1102-1103
Autor:
Juan Manuel Cardenas-Maestre, Sonia Panadero-Fajardo, Rosario M. Sánchez-Martín, Ana M. Pérez-López
Publikováno v:
Journal of Materials Chemistry. 21:12735
A novel strategy for the efficient and safe delivery of thiolated therapeutic cargoes into mammalian cells has been developed. For this purpose, polymeric microspheres have been successfully functionalised to become a sulfhydryl reactive delivery sys
Publikováno v:
Organic & Biomolecular Chemistry. 9:1720
An efficient solid phase strategy for the versatile functionalisation of xanthene dyes for conjugation and labelling of biomolecules is presented. The low cost, high purity and excellent spectral properties of the obtained materials provide an attrac