Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Juan M. Zolezzi"'
Autor:
Catalina Novoa, Paulina Salazar, Pedro Cisternas, Camila Gherardelli, Roberto Vera-Salazar, Juan M. Zolezzi, Nibaldo C. Inestrosa
Publikováno v:
Biological Research, Vol 55, Iss 1, Pp 1-18 (2022)
Abstract Alzheimer’s disease (AD), the most common form of dementia, is characterized by the accumulation of amyloid β (Aβ) and hyperphosphorylated tau protein aggregates. Importantly, Aβ and tau species are able to activate astrocytes and micro
Externí odkaz:
https://doaj.org/article/424aeb59d19f4d7bbaa09b827fd93235
Publikováno v:
European Medical Journal Neurology, Vol 8, Iss 1, Pp 108-114 (2020)
Neurodegenerative disorders constitute a worldwide concern attributable to the ageing of the human population. In this context, Alzheimer’s disease (AD) accounts for up to 70% of dementia cases worldwide. With no effective treatment available, new
Externí odkaz:
https://doaj.org/article/b15574747cd74f0aaedd913db56acb4f
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Teneurins (Tens) are a highly conserved family of proteins necessary for cell-cell adhesion. Tens can be cleaved, and some of their proteolytic products, such as the teneurin c-terminal associated-peptide (TCAP) and the intracellular domain (ICD), ha
Externí odkaz:
https://doaj.org/article/9ff0df7d81d44775b0fb75a9547035e9
Autor:
Areli M. Cárdenas-Oyarzo, Pamela A. Bocchieri-Oyarce, Cristian R. Méndez-Laport, Juan M. Zolezzi, Juvenal A. Ríos
Publikováno v:
Revista médica de Chile. 150:93-99
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7aad92299e27e0ddaf2beeb1ac5cc5f
https://doi.org/10.4067/s0034-98872022000100093
https://doi.org/10.4067/s0034-98872022000100093
Autor:
María Francisca Barake, Dunja D Roje, Juvenal Rios Leal, Francisco Garrido, Juan M Zolezzi, Benjamín García-Bloj, Valentina Zavala, Tomas P. Labbé
Publikováno v:
International Journal of Medical and Surgical Sciences. :1-11
Cancer constitutes the second most common cause of death worldwide and is expected to become the leading one, even above cardiovascular diseases. The understanding of the cellular and molecular basis of cancer has led not only to the proper developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e8aa8042c611be80976b0ccb21be2bf
https://doi.org/10.32457/ijmss.v8i3.1606
https://doi.org/10.32457/ijmss.v8i3.1606
Publikováno v:
Handbook of experimental pharmacology. 269
The cellular processes regulated by WNT signaling have been mainly studied during embryonic development and cancer. In the last two decades, the role of WNT in the adult central nervous system has been the focus of interest in our laboratory. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::46f7d344b25e6eaa967c716a0a783504
https://pubmed.ncbi.nlm.nih.gov/34486097
https://pubmed.ncbi.nlm.nih.gov/34486097
Autor:
Areli M, Cárdenas-Oyarzo, Pamela A, Bocchieri-Oyarce, Cristian R, Méndez-Laport, Juan M, Zolezzi, Juvenal A, Ríos
Publikováno v:
Revista medica de Chile. 150(1)
Professors James P. Allison and Tasuku Honjo were awarded with the 2018 Nobel Prize in Medicine for their contributions in cancer immunotherapy. The latter is a breakthrough in cancer therapy, aimed to overcome tumor-induced immunosuppression, leadin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f102395f34c6bad12f5467f1adf350d1
https://pubmed.ncbi.nlm.nih.gov/35856970
https://pubmed.ncbi.nlm.nih.gov/35856970
Autor:
Viviana I. Torres, Juan M. Zolezzi, Nibaldo C. Inestrosa, Pedro Cisternas, Guang William Wong, Milka Martinez
Publikováno v:
J Neurochem
Dysregulated Wnt signaling is linked to major neurodegenerative diseases, including Alzheimer disease (AD). In mouse models of AD, activation of the canonical Wnt signaling pathway improves learning/memory, but the mechanism for this remains unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a152f10999b61816c0f639bdc161ed
https://doi.org/10.1111/jnc.14608
https://doi.org/10.1111/jnc.14608
Publikováno v:
Pharmacology of the WNT Signaling System ISBN: 9783030854980
The cellular processes regulated by WNT signaling have been mainly studied during embryonic development and cancer. In the last two decades, the role of WNT in the adult central nervous system has been the focus of interest in our laboratory. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d654a86b5b53a89a3f8ff848b18ec06
https://doi.org/10.1007/164_2021_532
https://doi.org/10.1007/164_2021_532
