Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Juan M. Serrador"'
Publikováno v:
Cells, Vol 13, Iss 4, p 339 (2024)
Interactions among leukocytes and leukocytes with immune-associated auxiliary cells represent an essential feature of the immune response that requires the involvement of cell adhesion molecules (CAMs). In the immune system, CAMs include a wide range
Externí odkaz:
https://doaj.org/article/c1697a6cecd34612b5fe7cdcb4a3cebb
Autor:
Cristina Cacheiro-Llaguno, Elena Hernández-Subirá, Manuel D. Díaz-Muñoz, Manuel Fresno, Juan M. Serrador, Miguel A. Íñiguez
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13275 (2022)
Cyclooxygenase (COX) is the key enzyme in prostanoid synthesis from arachidonic acid (AA). Two isoforms, named COX-1 and COX-2, are expressed in mammalian tissues. The expression of COX-2 isoform is induced by several stimuli including cytokines and
Externí odkaz:
https://doaj.org/article/98861545e4594cb2a8d9085b4aa30915
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Nitric oxide (NO) and electrophilic cyclopentenone prostaglandins (CyPG) are local mediators that modulate cellular response to oxidative stress in different pathophysiological processes. In particular, there is increasing evidence about their functi
Externí odkaz:
https://doaj.org/article/1649e81fb77f45c2a4ae44e53ecd775b
Autor:
Ángel Bago, M. Laura Cayuela, Alba Gil, Enrique Calvo, Jesús Vázquez, Antonio Queiro, Francisco J. Schopfer, Rafael Radi, Juan M. Serrador, Miguel A. Íñiguez
Nitro-fatty acids (NO2-FAs) are unsaturated fatty acid nitration products that exhibit anti-inflammatory actions in experimental mouse models of autoimmune and allergic diseases. These electrophilic molecules interfere with intracellular signaling pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a195bad9214b24e207d6deb3235e4dcf
https://hdl.handle.net/10486/706995
https://hdl.handle.net/10486/706995
Autor:
Almudena García-Ortiz, Noa B Martín-Cofreces, Sales Ibiza, Ángel Ortega, Alicia Izquierdo-Álvarez, Antonio Trullo, Víctor M Victor, Enrique Calvo, Begoña Sot, Antonio Martínez-Ruiz, Jesús Vázquez, Francisco Sánchez-Madrid, Juan M Serrador
Publikováno v:
PLoS Biology, Vol 15, Iss 4, p e2000653 (2017)
The actin cytoskeleton coordinates the organization of signaling microclusters at the immune synapse (IS); however, the mechanisms involved remain poorly understood. We show here that nitric oxide (NO) generated by endothelial nitric oxide synthase (
Externí odkaz:
https://doaj.org/article/a9ffed663450463e90ba47b80fde4ad9
Autor:
Antonio Muñoz-Callejas, Juan M. Serrador, Angel Cogolludo, Luis Jesús Jiménez-Borreguero, Daniel Morales-Cano, Bianca Barreira, María de la Fuente-Fernández, Santos Castañeda, Rafael González-Tajuelo, Javier Silván, Elena González-Sánchez, Esther F Vicente-Rabaneda, Ana Urzainqui, Susana Cadenas, Marina Espartero-Santos, Carlos Gamallo, Francisco Perez-Vizcaino
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Arthritis & Rheumatology (Hoboken, N.j.)
instname
Arthritis & Rheumatology (Hoboken, N.j.)
Objective: Pulmonary arterial hypertension (PAH), one of the major complications of systemic sclerosis (SSc), is a rare disease with unknown etiopathogenesis and noncurative treatments. As mice deficient in P-selectin glycoprotein ligand 1 (PSGL-1) d
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Nitric oxide (NO) and electrophilic cyclopentenone prostaglandins (CyPG) are local mediators that modulate cellular response to oxidative stress in different pathophysiological processes. In particular, there is increasing evidence about their functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6d9ae7d5ce8ff2c6b9d23e5524fefb
http://hdl.handle.net/10261/267792
http://hdl.handle.net/10261/267792
Autor:
Maria D. Barea, Michel Bagnat, Gonzalo Herranz, Alejo E. Rodriguez-Fraticelli, Darren Gilmour, Catalina Grabowski, Gabriel Baonza, Silvia Campanario, Fernando Martín-Belmonte, Mariam Hachimi, Juan M. Serrador, Sergio Gomez-Lopez, Minerva Bosch-Fortea
Publikováno v:
Curr Biol
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
The actin cortex is involved in many biological processes and needs to be significantly remodeled during cell differentiation. Developing epithelial cells construct a dense apical actin cortex to carry out their barrier and exchange functions. The ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7721c26b9b2f36c778e665d94ff17b8d
http://hdl.handle.net/10261/269000
http://hdl.handle.net/10261/269000
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1502 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences
Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences
© 2020 by the authors
Ezrin, radixin and moesin proteins (ERMs) are plasma membrane (PM) organizers that link the actin cytoskeleton to the cytoplasmic tail of transmembrane proteins, many of which are adhesion receptors, in order to regulate t
Ezrin, radixin and moesin proteins (ERMs) are plasma membrane (PM) organizers that link the actin cytoskeleton to the cytoplasmic tail of transmembrane proteins, many of which are adhesion receptors, in order to regulate t
Autor:
Santos Castaeda, Juan M. Serrador, Bianca Barreira, Carlos Gamallo, Mara De la Fuente-Fernndez, Antonio Muoz-Callejas, Daniel Morales-Cano, Ana Urzainqui, Francisco Prez-Vizcano, Javier Silvn, Rafael Gonzlez-Tajuelo, Esther Vicente, Angel Cogolludo
Publikováno v:
Poster Presentations.
Background Pulmonary arterial hypertension (PAH) is a rare disease with unknown etiopathogenesis and no curative treatment [1]. PAH is one of the major complications of connective tissue diseases, and 7-15% of patients with systemic sclerosis (SSc) d