Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Juan M. Hurlé"'
Autor:
Ana I. Arroba, Lourdes Rodríguez-de la Rosa, Silvia Murillo-Cuesta, Laura Vaquero-Villanueva, Juan M. Hurlé, Isabel Varela-Nieto, Ángela M. Valverde
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 9, Pp 965-974 (2016)
Insulin-like growth factor-1 (IGF-1) is a growth factor with differentiating, anti-apoptotic and metabolic functions in the periphery, and anti-inflammatory properties in the nervous system. Mice that have mutations in the Igf1 gene, rendering the ge
Externí odkaz:
https://doaj.org/article/ddc52dfe94754a0480dc11ef47e728a9
Publikováno v:
Cells, Vol 1, Iss 3, Pp 428-448 (2012)
Autophagy is an evolutionarily conserved catabolic process by which cells degrade their own components through the lysosomal machinery. In physiological conditions, the mechanism is tightly regulated and contributes to maintain a balance between synt
Externí odkaz:
https://doaj.org/article/7d9e02715a1c4de1a0e66f2ee42be8e8
Autor:
Cristina Duarte-Olivenza, Goretti Moran, Juan M. Hurle, Carlos I. Lorda-Diez, Juan A. Montero
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-10 (2023)
Abstract Micromass cultures of embryonic limb skeletal progenitors replicate the tissue remodelling processes observed during digit morphogenesis. Here, we have employed micromass cultures in an in vitro assay to study the nature of cell degeneration
Externí odkaz:
https://doaj.org/article/c01873eabc68444b8ef8c264e1fcddbe
Following pioneering work by Harrison on amphibian limbs in the 1920s and by Saunders (1948) on the apical ridge in chick limbs, limb development became a classical model system for investigating such fundamental developmental issues as tissue intera
Autor:
Vanessa, Zuzarte-Luís, Juan M, Hurlé
Publikováno v:
The International journal of developmental biology. 46(7)
The sculpturing of shape in the developing limb together with the regression of the tail in anuran tadpoles constitute, perhaps, the most paradigmatic processes of programmed cell death. The study of these model systems has been of fundamental import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d77859ad22cc5e94cc519d4918b1758e
https://pubmed.ncbi.nlm.nih.gov/12455623
https://pubmed.ncbi.nlm.nih.gov/12455623
Publikováno v:
Cells, Vol 12, Iss 1, p 175 (2022)
Considering the importance of programmed cell death in the formation of the skeleton during embryonic development, the aim of the present study was to analyze whether regulated cell degeneration also accompanies the differentiation of embryonic limb
Externí odkaz:
https://doaj.org/article/d703a918595844ac9add0fd3beced4b7
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Digits develop in the distal part of the embryonic limb primordium as radial prechondrogenic condensations separated by undifferentiated mesoderm. In a short time interval the interdigital mesoderm undergoes massive degeneration to determine the form
Externí odkaz:
https://doaj.org/article/8014011aedc3431d91793f00b78a7509
Autor:
Nuria Torre-Pérez, Juan A. Montero, Vanessa Zuzarte-Luis, Juan A. García-Porrero, Nuria Rubio, Jerónimo Blanco, Juan F. Nistal, Juan M. Hurlé
Publikováno v:
Stem Cells & Development; Jan2009, Vol. 18 Issue 1, p27-36, 10p
Autor:
Cristina Sanchez-Fernandez, Carlos I. Lorda-Diez, Cristina Duarte-Olivenza, Juan M. Hurle, Juan A. Montero
Publikováno v:
Cells, Vol 10, Iss 4, p 911 (2021)
During limb formation in vertebrates with free digits, the interdigital mesoderm is eliminated by a massive degeneration process that involves apoptosis and cell senescence. The degradation process is preceded by intense DNA damage in zones located c
Externí odkaz:
https://doaj.org/article/ba9a6e0838d1412284f7383cd1839b65