Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Juan M. Falcón‑Pérez"'
Autor:
Ana Parra, Isabel Barranco, Pablo Martínez-Díaz, Esperanza González, Oihane E. Albóniga, Diana Cabrera, Juan M. Falcón-Pérez, Jordi Roca
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Seminal plasma (SP) is rich in extracellular vesicles (EVs), which are still poorly studied, especially in livestock species. To better understand their functional role in both spermatozoa and endometrial epithelial cells, proper characteriz
Externí odkaz:
https://doaj.org/article/b471ea28503441b88df4fa767e398f4a
Autor:
Ana Parra, Isabel Barranco, Pablo Martínez‑Díaz, Esperanza González, Oihane E. Albóniga, Diana Cabrera, Juan M. Falcón‑Pérez, Jordi Roca
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/711171e229a74fd08c25a9f86a2c033f
Autor:
Muireann Ní Bhaoighill, Juan M. Falcón‐Pérez, Félix Royo, Andrew R. Tee, Jason P. Webber, Elaine A. Dunlop
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 6, Pp n/a-n/a (2023)
Abstract Hyperactivation of mechanistic target of rapamycin complex 1 (mTORC1) is a feature of many solid tumours and is a key pathogenic driver in the inherited condition Tuberous Sclerosis Complex (TSC). Modulation of the tumour microenvironment by
Externí odkaz:
https://doaj.org/article/8c6f1cb68aad4a4b801ac9725eaa29a1
Autor:
Leticia Colyn, Gloria Alvarez-Sola, M. Ujue Latasa, Iker Uriarte, Jose M. Herranz, Maria Arechederra, George Vlachogiannis, Colin Rae, Antonio Pineda-Lucena, Andrea Casadei-Gardini, Federica Pedica, Luca Aldrighetti, Angeles López-López, Angeles López-Gonzálvez, Coral Barbas, Sergio Ciordia, Sebastiaan M. Van Liempd, Juan M. Falcón-Pérez, Jesus Urman, Bruno Sangro, Silve Vicent, Maria J. Iraburu, Felipe Prosper, Leonard J. Nelson, Jesus M. Banales, Maria Luz Martinez-Chantar, Jose J. G. Marin, Chiara Braconi, Christian Trautwein, Fernando J. Corrales, F. Javier Cubero, Carmen Berasain, Maite G. Fernandez-Barrena, Matias A. Avila
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Cholangiocarcinoma (CCA) is still a deadly tumour. Histological and molecular aspects of thioacetamide (TAA)-induced intrahepatic CCA (iCCA) in rats mimic those of human iCCA. Carcinogenic changes and therapeutic vulnerabilities i
Externí odkaz:
https://doaj.org/article/278c7dac66c24c988487ac905912005b
Autor:
Manuel Albert, Jesús Vázquez, Juan M. Falcón-Pérez, María A. Balboa, Marc Liesa, Jesús Balsinde, Susana Guerra
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Interferon-stimulated gene 15 (ISG15) is a 15-kDa ubiquitin-like modifier that binds to target proteins in a process termed ISGylation. ISG15, first described as an antiviral molecule against many viruses, participates in numerous cellular p
Externí odkaz:
https://doaj.org/article/c4616c3569d74d538924f381120bf40c
Publikováno v:
European Journal of Cell Biology, Vol 101, Iss 3, Pp 151226- (2022)
Cells release membrane-delimited particles into the environment. These particles are called “extracellular vesicles” (EVs), and EVs are present in fluids contacting cells, including body fluids and conditioned culture media. Because EVs change an
Externí odkaz:
https://doaj.org/article/e75bc711b64245c1bbe1baad364c520d
Autor:
Alex P. Shephard, Peter Giles, Mariama Mbengue, Amr Alraies, Lisa K. Spary, Howard Kynaston, Mark J. Gurney, Juan M. Falcón‐Pérez, Félix Royo, Zsuzsanna Tabi, Dimitris Parthimos, Rachel J. Errington, Aled Clayton, Jason P. Webber
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 12, Pp n/a-n/a (2021)
Abstract Histological assessment of prostate cancer is the key diagnostic test and can predict disease outcome. This is however an invasive procedure that carries associated risks, hence non‐invasive assays to support the diagnostic pathway are muc
Externí odkaz:
https://doaj.org/article/603d45562ec247eeb9de153068387d08
Autor:
Berta Roman-Canal, Jordi Tarragona, Cristian Pablo Moiola, Sònia Gatius, Sarah Bonnin, Maria Ruiz-Miró, José Enrique Sierra, Maria Rufas, Esperanza González, José M. Porcel, Antonio Gil-Moreno, Juan M. Falcón-Pérez, Julia Ponomarenko, Xavier Matias-Guiu, Eva Colas
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-14 (2019)
Abstract Background Colorectal cancer (CRC) is the third leading cause of cancer-related mortality worldwide. Current systematic methods for diagnosing have inherent limitations so development of a minimally-invasive diagnosis, based on the identific
Externí odkaz:
https://doaj.org/article/8f70c066268b41daadc1dd5eec6cc1ca
Autor:
Uta Erdbrügger, Charles J. Blijdorp, Irene V. Bijnsdorp, Francesc E. Borràs, Dylan Burger, Benedetta Bussolati, James Brian Byrd, Aled Clayton, James W. Dear, Juan M. Falcón‐Pérez, Cristina Grange, Andrew F. Hill, Harry Holthöfer, Ewout J. Hoorn, Guido Jenster, Connie R. Jimenez, Kerstin Junker, John Klein, Mark A. Knepper, Erik H. Koritzinsky, James M. Luther, Metka Lenassi, Janne Leivo, Inge Mertens, Luca Musante, Eline Oeyen, Maija Puhka, Martin E. vanRoyen, Catherine Sánchez, Carolina Soekmadji, Visith Thongboonkerd, Volkert vanSteijn, Gerald Verhaegh, Jason P. Webber, Kenneth Witwer, Peter S.T. Yuen, Lei Zheng, Alicia Llorente, Elena S. Martens‐Uzunova
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 7, Pp n/a-n/a (2021)
Abstract Urine is commonly used for clinical diagnosis and biomedical research. The discovery of extracellular vesicles (EV) in urine opened a new fast‐growing scientific field. In the last decade urinary extracellular vesicles (uEVs) were shown to
Externí odkaz:
https://doaj.org/article/11056fe3164342fca660fd4db4496dcd
Autor:
Iacopo Gesmundo, Barbara Pardini, Eleonora Gargantini, Giacomo Gamba, Giovanni Birolo, Alessandro Fanciulli, Dana Banfi, Noemi Congiusta, Enrica Favaro, Maria Chiara Deregibus, Gabriele Togliatto, Gaia Zocaro, Maria Felice Brizzi, Raul M. Luque, Justo P. Castaño, Maria Alessandra Bocchiotti, Simone Arolfo, Stefania Bruno, Rita Nano, Mario Morino, Lorenzo Piemonti, Huy Ong, Giuseppe Matullo, Juan M. Falcón-Pérez, Ezio Ghigo, Giovanni Camussi, Riccarda Granata
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
Extracellular vesicles (EVs) are implicated in the crosstalk between adipocytes and other metabolic organs, and an altered biological cargo has been observed in EVs from human obese adipose tissue (AT). Yet, the role of adipocyte-derived EVs in pancr
Externí odkaz:
https://doaj.org/article/6e988061edec4dbea6738ab3cdae512b