Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Juan M. Falcón‑Pérez"'
Autor:
Ana Parra, Isabel Barranco, Pablo Martínez-Díaz, Esperanza González, Oihane E. Albóniga, Diana Cabrera, Juan M. Falcón-Pérez, Jordi Roca
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Seminal plasma (SP) is rich in extracellular vesicles (EVs), which are still poorly studied, especially in livestock species. To better understand their functional role in both spermatozoa and endometrial epithelial cells, proper characteriz
Externí odkaz:
https://doaj.org/article/b471ea28503441b88df4fa767e398f4a
Autor:
Ana Parra, Isabel Barranco, Pablo Martínez‑Díaz, Esperanza González, Oihane E. Albóniga, Diana Cabrera, Juan M. Falcón‑Pérez, Jordi Roca
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/711171e229a74fd08c25a9f86a2c033f
Autor:
Muireann Ní Bhaoighill, Juan M. Falcón‐Pérez, Félix Royo, Andrew R. Tee, Jason P. Webber, Elaine A. Dunlop
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 6, Pp n/a-n/a (2023)
Abstract Hyperactivation of mechanistic target of rapamycin complex 1 (mTORC1) is a feature of many solid tumours and is a key pathogenic driver in the inherited condition Tuberous Sclerosis Complex (TSC). Modulation of the tumour microenvironment by
Externí odkaz:
https://doaj.org/article/8c6f1cb68aad4a4b801ac9725eaa29a1
Autor:
Leticia Colyn, Gloria Alvarez-Sola, M. Ujue Latasa, Iker Uriarte, Jose M. Herranz, Maria Arechederra, George Vlachogiannis, Colin Rae, Antonio Pineda-Lucena, Andrea Casadei-Gardini, Federica Pedica, Luca Aldrighetti, Angeles López-López, Angeles López-Gonzálvez, Coral Barbas, Sergio Ciordia, Sebastiaan M. Van Liempd, Juan M. Falcón-Pérez, Jesus Urman, Bruno Sangro, Silve Vicent, Maria J. Iraburu, Felipe Prosper, Leonard J. Nelson, Jesus M. Banales, Maria Luz Martinez-Chantar, Jose J. G. Marin, Chiara Braconi, Christian Trautwein, Fernando J. Corrales, F. Javier Cubero, Carmen Berasain, Maite G. Fernandez-Barrena, Matias A. Avila
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Cholangiocarcinoma (CCA) is still a deadly tumour. Histological and molecular aspects of thioacetamide (TAA)-induced intrahepatic CCA (iCCA) in rats mimic those of human iCCA. Carcinogenic changes and therapeutic vulnerabilities i
Externí odkaz:
https://doaj.org/article/278c7dac66c24c988487ac905912005b
Autor:
Manuel Albert, Jesús Vázquez, Juan M. Falcón-Pérez, María A. Balboa, Marc Liesa, Jesús Balsinde, Susana Guerra
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Interferon-stimulated gene 15 (ISG15) is a 15-kDa ubiquitin-like modifier that binds to target proteins in a process termed ISGylation. ISG15, first described as an antiviral molecule against many viruses, participates in numerous cellular p
Externí odkaz:
https://doaj.org/article/c4616c3569d74d538924f381120bf40c
Publikováno v:
European Journal of Cell Biology, Vol 101, Iss 3, Pp 151226- (2022)
Cells release membrane-delimited particles into the environment. These particles are called “extracellular vesicles” (EVs), and EVs are present in fluids contacting cells, including body fluids and conditioned culture media. Because EVs change an
Externí odkaz:
https://doaj.org/article/e75bc711b64245c1bbe1baad364c520d
Autor:
Kenneth W Witwer, Deborah CI Goberdhan, Lorraine O'Driscoll, Clotilde Théry, Joshua A Welsh, Cherie Blenkiron, Edit I Buzás, Dolores Di Vizio, Uta Erdbrügger, Juan M Falcón‐Pérez, Qing‐Ling Fu, Andrew F Hill, Metka Lenassi, Jan Lötvall, Rienk Nieuwland, Takahiro Ochiya, Sophie Rome, Susmita Sahoo, Lei Zheng
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 14, Pp n/a-n/a (2021)
Abstract The minimal information for studies of extracellular vesicles (EVs, MISEV) is a field‐consensus rigour initiative of the International Society for Extracellular Vesicles (ISEV). The last update to MISEV, MISEV2018, was informed by input fr
Externí odkaz:
https://doaj.org/article/b2c54b38158d445785e987c07249eb18
Autor:
Alex P. Shephard, Peter Giles, Mariama Mbengue, Amr Alraies, Lisa K. Spary, Howard Kynaston, Mark J. Gurney, Juan M. Falcón‐Pérez, Félix Royo, Zsuzsanna Tabi, Dimitris Parthimos, Rachel J. Errington, Aled Clayton, Jason P. Webber
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 12, Pp n/a-n/a (2021)
Abstract Histological assessment of prostate cancer is the key diagnostic test and can predict disease outcome. This is however an invasive procedure that carries associated risks, hence non‐invasive assays to support the diagnostic pathway are muc
Externí odkaz:
https://doaj.org/article/603d45562ec247eeb9de153068387d08
Autor:
Charles Williams, Raquel Pazos, Félix Royo, Esperanza González, Meritxell Roura-Ferrer, Aitor Martinez, Jorge Gamiz, Niels-Christian Reichardt, Juan M Falcón-Pérez
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Abstract Extracellular vesicles (EVs) are important mediators of cell-cell communication in a broad variety of physiological contexts. However, there is ambiguity around the fundamental mechanisms by which these effects are transduced, particularly i
Externí odkaz:
https://doaj.org/article/f0505b9ca36d474d9a060675efa0f354
Autor:
Berta Roman-Canal, Jordi Tarragona, Cristian Pablo Moiola, Sònia Gatius, Sarah Bonnin, Maria Ruiz-Miró, José Enrique Sierra, Maria Rufas, Esperanza González, José M. Porcel, Antonio Gil-Moreno, Juan M. Falcón-Pérez, Julia Ponomarenko, Xavier Matias-Guiu, Eva Colas
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-14 (2019)
Abstract Background Colorectal cancer (CRC) is the third leading cause of cancer-related mortality worldwide. Current systematic methods for diagnosing have inherent limitations so development of a minimally-invasive diagnosis, based on the identific
Externí odkaz:
https://doaj.org/article/8f70c066268b41daadc1dd5eec6cc1ca