Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Juan M. Castellano"'
Autor:
Elvira Rodríguez-Vázquez, Álvaro Aranda-Torrecillas, María López-Sancho, Juan M. Castellano, Manuel Tena-Sempere
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
The hypothalamus lies at the intersection of brain and hormonal mechanisms governing essential bodily functions, including metabolic/body weight homeostasis and reproduction. While metabolism and fertility are precisely regulated by independent neuro
Externí odkaz:
https://doaj.org/article/f25bfa3015124f008a342564176abbf4
Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3.
Autor:
Violeta Heras, Susana Sangiao-Alvarellos, Maria Manfredi-Lozano, María J Sanchez-Tapia, Francisco Ruiz-Pino, Juan Roa, Maribel Lara-Chica, Rosario Morrugares-Carmona, Nathalie Jouy, Ana P Abreu, Vincent Prevot, Denise Belsham, Maria J Vazquez, Marco A Calzado, Leonor Pinilla, Francisco Gaytan, Ana C Latronico, Ursula B Kaiser, Juan M Castellano, Manuel Tena-Sempere
Publikováno v:
PLoS Biology, Vol 17, Iss 11, p e3000532 (2019)
Mkrn3, the maternally imprinted gene encoding the makorin RING-finger protein-3, has recently emerged as putative pubertal repressor, as evidenced by central precocity caused by MKRN3 mutations in humans; yet, the molecular underpinnings of this key
Externí odkaz:
https://doaj.org/article/ef93c7a3add44a31bc7144e1863b1fe4
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism.
Publikováno v:
Current Opinion in Endocrine and Metabolic Research. 14:78-84
Nutritional conditions and the amount of body energy reserves play a critical role in regulating the onset of puberty. Thus, extreme situations of energy imbalance, ranging from malnutrition to obesity, are associated with alterations in pubertal tim
Autor:
C. Dieguez, Alfonso Paredes, E. Torres, Rafael Pineda, Heras, Juan Carlos Roa, Ismael Velasco, María Jesús Vázquez, F Gaytan, M. Tena-Sempere, Daniela Fernandois, Rubio M, Francisco Ruiz-Pino, María S. Avendaño, Núria Casals, Elvira Rodríguez-Vázquez, Denise D. Belsham, Miguel López, Juan M. Castellano, Leonor Pinilla
Publikováno v:
Yearbook of Paediatric Endocrinology.
Autor:
Ana Aranda, Denise D. Belsham, Véronique Bozon, Maria Luisa Brandi, Giulia Brigante, Gilles Bruneau, Sally A. Camper, Livio Casarini, Juan M. Castellano, Leonard Y.M. Cheung, Luisella Cianferotti, Frédérique Clément, Lique M. Coolen, Pascale Crépieux, Prasad Dalvi, Lily Q. Dong, Shereen Ezzat, Tatiana Fiordelisio, Robert C. Fowkes, Laurine Gagniac, Nathalie Gallay, Zu-hua Gao, Peter D. Gluckman, Karen Gomez-Hernandez, Robert L. Goodman, Florian Guillou, Jason T. Hadley, Mark A. Hanson, Aylin C. Hanyaloglu, Tomohiro Ishii, Jo Ann Janovick, Frédéric Jean-Alphonse, José Nicolás Jiménez, Constanza Contreras Jurado, Nancy Kaddour, Michael N. Lehman, Jun-Li Liu, Zhenqi Liu, Neruja Loganathan, Felicia M. Low, Olaia Martínez-Iglesias, Craig A. McArdle, Emma K. Mcilwraith, Moises Mercado, Francesco De Pascali, Lucie P. Pellissier, María Inés Pérez Millán, Hanna Pincas, Anne Poupon, Pauline Raynaud, Eric Reiter, Elvira Rodríguez-Vázquez, Cecilia Romagnoli, Frederique Ruf-Zamojski, Lidia Ruiz-Llorente, Jiyoon Ryu, Daniele Santi, Stuart C. Sealfon, Manuela Simoni, Shifa Tahir, Toru Tateno, Manuel Tena-Sempere, Nimbe Torres, Armando R. Tovar, Andy Tran, Krasimira Tsaneva-Atanasova, Judith L. Turgeon, Alfredo Ulloa-Aguirre, Ariana Vargas-Castillo, Jean-Pierre Vilardaga, Margaritis Voliotis, Alex D. White, Viktoria Xega, Romain Yvinec, Teresa Zariñán
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::376618ce6a4e0872577653638c8979e0
https://doi.org/10.1016/b978-0-12-819801-8.09992-0
https://doi.org/10.1016/b978-0-12-819801-8.09992-0
Autor:
Raúl M. Luque, Juan M. Castellano, María Jesús Vázquez, Francisco Ruiz-Pino, Miguel A. Sánchez-Garrido, Ana I. Pozo-Salas, Manuel Tena-Sempere
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
In addition to its essential role in the physiological control of longitudinal growth, growth-hormone (GH) is endowed with relevant metabolic functions, including anabolic actions in muscle, lipolysis in adipose-tissue and glycemic modulation. Adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d044b68878d7dc40d0162198a9005d
https://hdl.handle.net/10668/3890
https://hdl.handle.net/10668/3890
Autor:
Rafael Pineda, David Garcia-Galiano, María Jesús Vázquez, Patricia Seoane-Collazo, Heras, Noelia Martínez-Sánchez, Alexia Barroso, Francisco Ruiz-Pino, Juan M. Castellano, Manuel Tena-Sempere, T. Ilhan, C. Dieguez, Matti Poutanen, Leonor Pinilla, F Gaytan, Juan Carlos Roa, Miguel López, S. Leon, anfredi-Lozano M
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(45):E10758-E10767
Conditions of metabolic distress, from malnutrition to obesity, impact, via as yet ill-defined mechanisms, the timing of puberty, whose alterations can hamper later cardiometabolic health and even life expectancy. AMP-activated protein kinase (AMPK),
Autor:
Maria Manfredi-Lozano, Daniela Fernandois, Miguel A. Sánchez-Garrido, Inmaculada Velasco, Violeta Heras, Juan Carlos Roa, Juan M. Castellano, Alexia Barroso, Leonor Pinilla, María Jesús Vázquez, Francisco Ruiz-Pino, Manuel Tena-Sempere
Publikováno v:
Endocrinology. 159:1005-1018
Obesity and its comorbidities are reaching epidemic proportions worldwide. Maternal obesity is known to predispose the offspring to metabolic disorders, independently of genetic inheritance. This intergenerational transmission has also been suggested
Autor:
Delphine Franssen, Desiree Miceli, Giancarlo Panzica, Manuel Tena-Sempere, Francisco Ruiz-Pino, Alice Farinetti, Juan M. Castellano, María Jesús Vázquez
The timing of puberty is highly sensitive to environmental factors, including endocrine disruptors. Among them, bisphenol A (BPA) has been previously analyzed as potential modifier of puberty. Yet, disparate results have been reported, with BPA advan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c294b6f712d17dee34998438912a3eef
https://hdl.handle.net/10668/15322
https://hdl.handle.net/10668/15322