Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Juan M, Arnoletti"'
Autor:
Leeana D. Peters, Wen-I Yeh, Juan M. Arnoletti, Matthew E. Brown, Amanda L. Posgai, Clayton E. Mathews, Todd M. Brusko
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The autoimmune pathogenesis of type 1 diabetes (T1D) involves cellular infiltration from innate and adaptive immune subsets into the islets of Langerhans within the pancreas; however, the direct cytotoxic killing of insulin-producing β-cells is thou
Externí odkaz:
https://doaj.org/article/84a0c1b62a9c4bd1bd78d647cf57931b
Autor:
Matthew E. Brown, Leeana D. Peters, Seif R. Hanbali, Juan M. Arnoletti, Lindsey K. Sachs, Kayla Q. Nguyen, Emma B. Carpenter, Howard R. Seay, Christopher A. Fuhrman, Amanda L. Posgai, Melanie R. Shapiro, Todd M. Brusko
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Regulatory T cell (Treg) adoptive cell therapy (ACT) represents an emerging strategy for restoring immune tolerance in autoimmune diseases. Tregs are commonly purified using a CD4+CD25+CD127lo/- gating strategy, which yields a mixed population: 1) ce
Externí odkaz:
https://doaj.org/article/ee8774329b694e21a6e707bc96062b84
Autor:
Puchong Thirawatananond, Matthew E. Brown, Lindsey K. Sachs, Juan M. Arnoletti, Wen-I Yeh, Amanda L. Posgai, Melanie R. Shapiro, Yi-Guang Chen, Todd M. Brusko
Co-stimulation serves as a critical checkpoint for T cell development and activation, and several genetic variants affecting co-stimulatory pathways confer risk for autoimmune diseases. A single nucleotide polymorphism in CD226 (rs763361; G307S) has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b0299f82ef86cd7055a30369fba428f
https://doi.org/10.1101/2022.06.02.494443
https://doi.org/10.1101/2022.06.02.494443
Autor:
Matthew E, Brown, Leeana D, Peters, Seif R, Hanbali, Juan M, Arnoletti, Lindsey K, Sachs, Kayla Q, Nguyen, Emma B, Carpenter, Howard R, Seay, Christopher A, Fuhrman, Amanda L, Posgai, Melanie R, Shapiro, Todd M, Brusko
Publikováno v:
Frontiers in immunology. 13
Regulatory T cell (Treg) adoptive cell therapy (ACT) represents an emerging strategy for restoring immune tolerance in autoimmune diseases. Tregs are commonly purified using a CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc48a41169ccd1c2f7242ac63979071a
https://pubmed.ncbi.nlm.nih.gov/35693814
https://pubmed.ncbi.nlm.nih.gov/35693814
Autor:
Todd M. Brusko, Seif R. Hanbali, Matthew E. Brown, Emma B. Carpenter, Juan M. Arnoletti, Luz Marina Gomez Rodriguez
Publikováno v:
Diabetes. 70
Human regulatory T cells (Tregs) are essential for the suppression of autoimmunity and adoptive cell therapy has been proposed as a means for restoring durable immune tolerance in T1D. The rare nature of this subset requires the isolation and in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bc70f82ead440b643bdcae8653b336d
https://doi.org/10.2337/db21-192-lb
https://doi.org/10.2337/db21-192-lb