Illuminating a Solvent-Dependent Hierarchy for Aromatic CH/π Complexes with Dynamic Covalent Glyco-Balances

Autor: Laura Díaz-Casado, Alejandro Villacampa, Francisco Corzana, Jesús Jiménez-Barbero, Ana M. Gómez, Andrés G. Santana, Juan Luis Asensio

Publikováno v: JACS Au, Vol 4, Iss 2, Pp 476-490 (2024)

Externí odkaz: https://doaj.org/article/04d92c94155747c39bbf1047780ad06a

Thioglycoligase derived from fungal GH3 β-xylosidase is a multi-glycoligase with broad acceptor tolerance

Autor: Manuel Nieto-Domínguez, Beatriz Fernández de Toro, Laura I. de Eugenio, Andrés G. Santana, Lara Bejarano-Muñoz, Zach Armstrong, Juan Antonio Méndez-Líter, Juan Luis Asensio, Alicia Prieto, Stephen G. Withers, Francisco Javier Cañada, María Jesús Martínez

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

Thioglycoligases have proved useful for bonding carbohydrates to non-sugar acceptors, however, the scope of these biocatalysts is usually limited. Here, the authors engineer a xylosidase into a thioglycoligase with the ability to form O-, N-, S- and

Externí odkaz: https://doaj.org/article/b6f5a98554ec4b30ad3593c389e9d6e2

Transglycosylation products generated by Talaromyces amestolkiae GH3 β-glucosidases: effect of hydroxytyrosol, vanillin and its glucosides on breast cancer cells

Autor: Juan Antonio Méndez-Líter, Isabel Tundidor, Manuel Nieto-Domínguez, Beatriz Fernández de Toro, Andrés González Santana, Laura Isabel de Eugenio, Alicia Prieto, Juan Luis Asensio, Francisco Javier Cañada, Cristina Sánchez, María Jesús Martínez

Publikováno v: Microbial Cell Factories, Vol 18, Iss 1, Pp 1-12 (2019)

Abstract Background Transglycosylation represents one of the most promising approaches for obtaining novel glycosides, and plant phenols and polyphenols are emerging as one of the best targets for creating new molecules with enhanced capacities. Thes

Externí odkaz: https://doaj.org/article/f5e2ca18d5b24b469d97a722ec80dd54

Glycosyl Oxocarbenium Ions: Structure, Conformation, Reactivity, and Interactions

Autor: Yves Blériot, Ana Ardá, Antonio Franconetti, Jesús Jiménez-Barbero, Sébastien Thibaudeau, Juan Luis Asensio

Publikováno v: Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Addi. Archivo Digital para la Docencia y la Investigación
instname
Universidad de Cantabria (UC)
Digital.CSIC. Repositorio Institucional del CSIC
Accounts of Chemical Research

Carbohydrates (glycans, saccharides, and sugars) are essential molecules in all domains of life. Research on glycoscience spans from chemistry to biomedicine, including material science and biotechnology. Access to pure and well-defined complex glyca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36146a5f98e4426f421103ec4d93ff73
http://hdl.handle.net/10810/51741

Thioglycoligase derived from fungal GH3 β-xylosidase is a multi-glycoligase with broad acceptor tolerance

Autor: Zach Armstrong, Stephen G. Withers, Francisco Javier Cañada, Beatriz Fernández de Toro, María Jesús Martínez, Juan Luis Asensio, Manuel Nieto-Domínguez, Juan Antonio Méndez-Líter, Laura I. de Eugenio, Alicia Prieto, Lara Bejarano-Muñoz, Andrés G. Santana

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications, 11
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications

16 p.-6 fig.-2 tab.
The synthesis of customized glycoconjugates constitutes a major goal for biocatalysis. To this end, engineered glycosidases have received great attention and, among them, thioglycoligases have proved useful to connect carbohy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6e5ffa7712222934c821e538f7e915
http://hdl.handle.net/10261/220760