Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Juan José Sanz-Ezquerro"'
Autor:
Alejandra Escós, Ester Diaz-Mora, Michael Pattison, Pilar Fajardo, Diego González-Romero, Ana Risco, José Martín-Gómez, Éric Bonneil, Nahum Sonenberg, Seyed Mehdi Jafarnejad, Juan José Sanz-Ezquerro, Steven C Ley, Ana Cuenda
Publikováno v:
eLife, Vol 12 (2023)
Evidence implicating p38γ and p38δ (p38γ/p38δ) in inflammation are mainly based on experiments using Mapk12/Mapk13-deficient (p38γ/δKO) mice, which show low levels of TPL2, the kinase upstream of MKK1–ERK1/2 in myeloid cells. This could obscu
Externí odkaz:
https://doaj.org/article/465cca0c4aa64ff59473c25390cfe9f4
Autor:
Ester Díaz-Mora, Diego González-Romero, Marta Meireles-da-Silva, Juan José Sanz-Ezquerro, Ana Cuenda
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Mitogen- and Stress-activated Kinase (MSK) 1 is a nuclear protein, activated by p38α Mitogen-Activated Kinase (MAPK) and extracellular signal-regulated kinase (ERK1/2), that modulate the production of certain cytokines in macrophages. Using knockout
Externí odkaz:
https://doaj.org/article/383282837e1140619fdc4453c2486ce9
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52781 (2012)
An often overlooked aspect of digit development is the special nature of the terminal phalanx, a specialized structure with characteristics distinct from other phalanges, for example the presence of ectodermal derivatives such as nails and claws. Her
Externí odkaz:
https://doaj.org/article/d64a2bfaf12f4a508ca50141a2097fd0
Autor:
Alejandra, Escós, José, Martín-Gómez, Diego, González-Romero, Ester, Díaz-Mora, Rosario, Francisco-Velilla, Cesar, Santiago, José M, Cuezva, Sonia, Domínguez-Zorita, Encarnación, Martínez-Salas, Nahum, Sonenberg, Juan José, Sanz-Ezquerro, Seyed Mehdi, Jafarnejad, Ana, Cuenda
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(35)
p38γ and p38δ (p38γ/p38δ) regulate inflammation, in part by controlling tumor progression locus 2 (TPL2) expression in myeloid cells. Here, we demonstrate that TPL2 protein levels are dramatically reduced in p38γ/p38δ-deficient (p38γ/δ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac4bd8629ae9f8152227b7f5b365ce6f
https://pubmed.ncbi.nlm.nih.gov/35994673
https://pubmed.ncbi.nlm.nih.gov/35994673
Autor:
Alejandra Escós, Ester Díaz-Mora, Michael Pattison, Pilar Fajardo, Diego González-Romero, Ana Risco, José Martín-Gómez, Éric Bonneil, Nahum Sonenberg, Seyed Mehdi Jafarnejad, Juan José Sanz-Ezquerro, Steven C. Ley, Ana Cuenda
Evidence implicating p38γ and p38δ (p38γ/p38δ) in inflammation are mainly based on experiments using p38γ/p38δ deficient (p38γ/δ-/-) mice, which show low levels of TPL2, the kinase upstream of MKK1-ERK1/2 in myeloid cells. This could obscure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72e4f49d4069c6219b194e7fdd582af3
https://doi.org/10.1101/2022.12.09.519777
https://doi.org/10.1101/2022.12.09.519777
Autor:
Alejandra Escós, José Martín-Gómez, Diego González-Romero, Ester Díaz-Mora, Rosario Francisco-Velilla, Cesar Santiago, José M. Cuezva, Sonia Domínguez-Zorita, Encarnación Martínez-Salas, Nahum Sonenberg, Juan José Sanz-Ezquerro, Seyed Mehdi Jafarnejad, Ana Cuenda
Publikováno v:
Escós, A, Martín-Gómez, J, González-Romero, D, Díaz-Mora, E, Francisco-Velilla, R, Santiago, C, Cuezva, J M, Domínguez-Zorita, S, Martínez-Salas, E, Sonenberg, N, Sanz-Ezquerro, J J, Jafarnejad, S M & Cuenda, A 2022, ' TPL2 kinase expression is regulated by the p38γ/p38δ-dependent association of aconitase-1 with TPL2 mRNA ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 35, e2204752119 . https://doi.org/10.1073/pnas.2204752119
p38γ and p38δ (p38γ/p38δ) regulate inflammation, in part by controlling tumor progression locus 2 (TPL2) expression in myeloid cells. Here, we demonstrate that TPL2 protein levels are dramatically reduced in p38γ/p38δ-deficient (p38γ/δ2/2) ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a35c6f5b4f03de39f461975b160f133
https://hdl.handle.net/10486/707245
https://hdl.handle.net/10486/707245
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2321
The intravenous challenge model of Candida albicans infection in mice is a well-established procedure that mirrors disseminated candidiasis in humans. In this model, in which the fungus is delivered into the bloodstream causing a systemic infection,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::959f9721e9084f62a6c87b1c6a12cff9
https://pubmed.ncbi.nlm.nih.gov/34048008
https://pubmed.ncbi.nlm.nih.gov/34048008
Autor:
Victoria Shabardina, Pedro Romero Charria, Gonzalo Bercedo Saborido, Ester Diaz-Mora, Ana Cuenda, Iñaki Ruiz-Trillo, Juan Jose Sanz-Ezquerro
Publikováno v:
Open Biology, Vol 13, Iss 1 (2023)
p38 kinases are key elements of the cellular stress response in animals. They mediate the cell response to a multitude of stress stimuli, from osmotic shock to inflammation and oncogenes. However, it is unknown how such diversity of function in stres
Externí odkaz:
https://doaj.org/article/47e1ad07bd3b48558b34140d03958341