Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Juan José Pérez Ruixo"'
Autor:
Anna Dari, Philippe Jacqmin, Yuki Iwaki, Martine Neyens, Mathieu Le Gars, Jerald Sadoff, Karin Hardt, Javier Ruiz‐Guiñazú, Juan José Pérez‐Ruixo
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 10, Pp 1485-1498 (2023)
Abstract Mechanistic model‐based simulations can be deployed to project the persistence of humoral immune response following vaccination. We used this approach to project the antibody persistence through 24 months from the data pooled across five c
Externí odkaz:
https://doaj.org/article/e5c516261c6749c5aae3b158bce0490e
Publikováno v:
Clinical Pharmacology & Therapeutics. 113:692-703
Autor:
Anna Dari, Muriel Boulton, Martine Neyens, Mathieu Le Gars, Belén Valenzuela, Georgi Shukarev, Vicky Cárdenas, Javier Ruiz‐Guiñazú, Jerald Sadoff, Richard M. W. Hoetelmans, Juan José Pérez Ruixo
Publikováno v:
Clinical Pharmacology & Therapeutics. 113:380-389
Understanding persistence of humoral immune responses elicited by vaccination against coronavirus disease 2019 (COVID-19) is critical for informing the duration of protection and appropriate booster timing. We developed a mechanistic model to charact
Autor:
Juan-José Pérez-Ruixo, Yaowei Zhu, Martine Neyens, Marie-Helene Jouvin, Sindhu Ramchandren, Yan Xu, Jocelyn Leu, Anne-Gaëlle Dosne, Yuan Xiong, Belén Valenzuela, Leona Ling, Partha Nandy, Hong Sun
Publikováno v:
Sunday, April 23.
Publikováno v:
Therapeutic Drug Monitoring. 36:317-325
Several factors such as low therapeutic index, large interindividual variability in systemic exposure, and the relationships between exposure and toxicity for sorafenib could justify its therapeutic drug monitoring (TDM). To support TDM, a selective
Autor:
Antonio Brugarolas Masllorens, Manuel Sureda, Juan José Pérez Ruixo, Pedro Bretcha-Boix, Carlos Dussan, José Farré-Alegre
Publikováno v:
Clinical and Translational Oncology. 12:437-442
Peritoneal carcinomatosis is a relatively frequent situation in the natural history of colorectal cancer and is associated with a dismal prognosis. Promising results have been shown after radical cytoreduction followed by intraperitoneal chemohyperth
Autor:
Anne‐Gaëlle Dosne, Elodie Valade, Kim Stuyckens, Peter De Porre, Anjali Avadhani, Anne O’Hagan, Lilian Y. Li, Daniele Ouellet, Ruben Faelens, Quentin Leirens, Italo Poggesi, Juan Jose Perez Ruixo
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 5, Pp 569-580 (2022)
Abstract A population pharmacokinetic (PK)–pharmacodynamic (PD) model was developed using data from 345 patients with cancer. The population PK‐PD model evaluated the effect of erdafitinib total and free plasma concentrations on serum phosphate c
Externí odkaz:
https://doaj.org/article/d207019ca52a4083a1ee53c5220eb93b
Autor:
Gustavo, Camps-Valls, Begoña, Porta-Oltra, Emilio, Soria-Olivas, José David, Martín-Guerrero, Antonio José, Serrano-López, Juan José, Pérez-Ruixo, Nicolás Víctor, Jiménez-Torres
Publikováno v:
IEEE Transactions on Biomedical Engineering. 50:442-448
This paper proposes the use of neural networks for individualizing the dosage of cyclosporine A (CyA) in patients who have undergone kidney transplantation. Since the dosing of CyA usually requires intensive therapeutic drug monitoring, the accurate
Autor:
Pilar Azagra Ros, Nicolás Victor Jiménez Torres, Javier García Conde Bru, Vicente Germán Casabó Alós, Juan José Pérez Ruixo
Publikováno v:
Revista de Oncología. 4:139-146
Nuestro objetivo es comparar la efectividad del inicio del tratamiento con rHu-GCSF transcurridas 24 ho-ras (dia +1) desde la reinfusion de celulas precursoras hematopoyeticas de sangre periferica (CPHSP) con la administracion de rHu-GCSF 5 dias (dia
Autor:
Gustavo Camps Valls, Antonio López, José David Martín Guerrero, Juan José Pérez Ruixo, Emilio Soria Olivas, N. Víctor Jiménez Torres
Publikováno v:
Computers in biology and medicine. 33(4)
The external administration of recombinant human erythropoietin is the chosen treatment for those patients with secondary anemia due to chronic renal failure undergoing periodic hemodialysis. The goal is to carry out an individualised prediction of t